June 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study tested a microneedle patch on rabbit and pig models to support skin regeneration, revealing that the treatment accelerated wound closure, reduced scar formation, and promoted hair-bearing tissue and follicle growth, suggesting a trauma-guided framework for skin restoration.
1 citations
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January 2010 This study found that using minoxidil 2% as a mesotherapy injection showed more significant improvement in treating androgenetic alopecia in female patients than topical application.
49 citations
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August 2016 in “Aesthetic Surgery Journal” This study found that micro-needling with cosmeceuticals or platelet-rich plasma significantly improved wrinkles, skin laxity, scar softening, and hair growth over 12 months, with minimal side effects, and that the best results occur with pigment and platelet massaging between 5 to 30 minutes post-treatment.
This review highlights that microtrauma, involving small intentional skin injuries, shows promise in stimulating hair growth in non-scarring alopecias by enhancing immune responses and increasing growth factor release, with methods like microneedling and PRP demonstrating efficacy.
5 citations
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February 2012 in “Aesthetic Plastic Surgery” This case report introduces a novel instance of long-term cutaneous neoplastic degeneration following artificial hair implantation, a previously unreported complication in such procedures.