24 citations
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October 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that the LH response to nafarelin effectively distinguished gonadotropin deficiency from constitutional delay of puberty, performing comparably to the sleep test and offering certain advantages.
15 citations
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May 2010 in “Pediatrics in Review” This article reviews the normal and delayed maturation of the HPG axis and pubertal development in boys and girls, emphasizing clinical aspects of diagnosing and managing delayed puberty, but it reports no new clinical findings.
21 citations
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April 2010 in “Pediatrics in Review” This article reviews various causes and diagnostic approaches to delayed puberty in boys and girls and does not report any new clinical findings; it emphasizes the importance of distinguishing between different underlying conditions.
19 citations
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March 2004 in “The Journal of Clinical Endocrinology & Metabolism” This study suggests that combining testosterone and letrozole may accelerate puberty in boys with constitutional delay by increasing serum androgen bioactivity and facilitating pubertal progression.
January 2016 in “Springer eBooks” A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.