Delayed Puberty

May 2010 in “ Pediatrics in Review ”

Paul B. Kaplowitz

hypothalamic-pituitary-gonadal axis constitutional delayed puberty gonadotropin primary ovarian failure Kallmann syndrome Turner syndrome testosterone therapy estrogen therapy

Studysummary This article reviews the normal and delayed maturation of the HPG axis and pubertal development in boys and girls, emphasizing clinical aspects of diagnosing and managing delayed puberty, but it reports no new clinical findings.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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October 2022 in “Medical Clinical Update Journal”

This case report describes a 7.5-year-old girl with precocious puberty displaying significant secondary sexual development and advanced bone age, treated monthly with Leuprolide.