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This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

This study found that Notch-related genes, including Notch1 and Notch2, and their ligands and regulators, have distinct patterns of expression during mouse hair vibrissa follicle development and the adult hair cycle.

This study found that compound 2 from Polygonum multiflorum increased dermal papilla cell proliferation and vibrissa follicle hair-fiber length more effectively than minoxidil in vitro, suggesting potential for alopecia treatment.

In this study, KY19382 was observed to promote hair regeneration and de novo hair follicle formation in mice by activating Wnt/β-catenin signaling, suggesting its potential as a therapeutic for alopecia.

This study found that dermal papilla cells and bulge stem cells can potentially be used to reconstruct hair follicles, as hair follicle-like structures were observed after culturing under a rat's renal capsule.