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GlossaryVascularity

indicates visibility and prominence of blood vessels in tissue

Vascularity refers to the degree to which blood vessels are visible and prominent in a particular area of the body. It is often used to describe the appearance of veins under the skin, which can become more noticeable with increased blood flow, reduced body fat, or enhanced muscle definition. In a medical context, good vascularity can indicate healthy circulation, while poor vascularity might suggest issues with blood flow or vascular health.

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community Is it possible to have low scalp vascularity??

in Treatment 3 upvotes 6 months ago

The user is using topical dutasteride, finasteride, minoxidil, and tretinoin but seeing no results or side effects. They also microneedle every two weeks but experience little bleeding, questioning if a thick scalp is preventing treatment effectiveness.

community The Korean began to suspect something. But they understood the mechanism to some extent. ( Cold shock therapy promotes hair growth in association with upregulation of cold-inducible RNA-binding protein and vascular endothelial growth factor)

in Research 86 upvotes 3 weeks ago

Cold shock therapy may promote hair growth by stimulating follicular muscles and affecting stem cells. The exact mechanisms and full range of elements involved are not yet fully understood.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 4 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Proposed new pathogenesis model for androgenetic alopecia (AGA)

in Research/Science 8 upvotes 1 year ago

The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

in Research/Science 13 upvotes 7 months ago

A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

community How to Switch from Finasteride to Dutasteride according to literature.

in Research/Science 53 upvotes 6 months ago

Switching from finasteride to dutasteride involves gradually increasing dutasteride while decreasing finasteride. Studies show dutasteride 0.5 mg daily can improve hair density in men unresponsive to finasteride.

community Improve my stack (without Minoxidil)

in Product 37 upvotes 1 year ago

The conversation discusses improving a hair loss treatment stack without using Minoxidil. Microneedling is suggested, Alpecin is deemed ineffective, and there are concerns about the safety of Minoxidil compared to finasteride.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Scientific evidence for Peppermint & Rosemary oils + My Experience

in Research/Science 114 upvotes 2 years ago

Natural treatments for hair loss, specifically peppermint oil and rosemary oil; how they can be used as a supplementary or alternative treatment to pharmaceuticals such as finasteride and minoxidil; and the personal experience of the user Divallo, who has seen an increase in density and thickness after using these oils for around 2.5 years. The post also touches on the potential antifungal properties of the oils and their effects on cutaneous blood flow.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community Why can't you drink caffeine after PRP?

in Treatment 9 upvotes 2 years ago

The conversation discusses avoiding caffeine after Platelet-Rich Plasma (PRP) treatment for hair loss because caffeine is a vasoconstrictor, which can reduce blood flow and hinder the healing process that PRP aims to promote.

community Could low blood flow to the head cause an increased rate of thinning?

in Chat 27 upvotes 3 years ago

The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hair loss.

community Can’t tolerate oral fin at any dosage, help me brainstorm a treatment plan.

in Treatment 9 upvotes 7 months ago

The user cannot tolerate oral finasteride and is considering topical finasteride, minoxidil, microneedling, and RU58841 as alternative treatments for hair loss. They seek advice on whether these options are worth trying.

community My baby is balding! (Norwood 7)

in Satire 1163 upvotes 1 year ago

The conversation is a satirical discussion about a baby with hair loss using adult hair loss treatments like finasteride, minoxidil, and ketoconazole, as well as dermarolling, scalp massages, and plans for PRP sessions. Suggestions include various other treatments and humorous advice, reflecting the satire of the situation.

community Debunking Androgenetic Theory (Hair Transplants)

in Research/Science 25 upvotes 1 year ago

The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

community Despite some extremely difficult circumstances (temples starting to recede at 19, than getting fin sides that wouldn't go away after stopping) I have nothing but good things to share 3 years into this journey

in Update 57 upvotes 4 years ago

The user started using minoxidil at 19 for receding temples and saw good regrowth, but experienced severe and lasting sexual side effects from finasteride. They improved their condition with pelvic floor exercises, a healthy lifestyle, and continued using minoxidil with dermarolling, which led to further hair regrowth.

community Is peppermint oil + dermarolling more effective than minoxidal?

in Treatment 6 upvotes 6 years ago

The conversation discusses the effectiveness of peppermint oil and dermarolling for hair regrowth, with one person suggesting that only dermarolling is effective and comparing peppermint oil's effectiveness to that of an egg.

community Efficacy of Dut at 0.5mg VS 1mg VS 2.5mg

in Finasteride/Dutasteride 49 upvotes 1 month ago

Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

community How to prevent hair loss while taking creatine?

in Research/Science 4 upvotes 4 months ago

A user is concerned about hair loss from creatine and asks for precautions, mentioning treatments like Minoxidil, finasteride, and ketoconazole shampoo. Replies vary, with some users sharing personal experiences and others dismissing the concern.

community How To Switch from Finasteride to Dutasteride (according to literature)

in Research/Science 11 upvotes 5 months ago

Switching from finasteride to dutasteride for hair loss treatment. Dutasteride is suggested as a more effective alternative.

community Anyone using oral castor oil in their stack?

in Treatment 3 upvotes 6 months ago

The conversation discusses using oral castor oil as a hair growth stimulant for beard and scalp hair. One user questions its use, noting castor oil is typically a laxative in the Philippines.

community Caffiene shampoos left in for 2 minutes show comparable results to Minoxidil, and may work differently than Minoxidil, which can add to your stack, or work for non responders

in Research/Science 42 upvotes 6 months ago

Caffeine shampoos show comparable results to Minoxidil and may enhance its effects when used together. Caffeine can be detected in the scalp up to 24 hours after a 2-minute application, making it an affordable treatment option.

community What About Phytosterol Alternatives - Rice Bran Oil - Natural DHT Blockers

in Research/Science 4 upvotes 7 months ago

The conversation discusses natural DHT blockers like rice bran oil, which may reduce 5α-reductase activity similarly to Minoxidil and Dutasteride. One user argues that finasteride is more reliable and effective than natural alternatives.

community 15 months fin and keto, thinking about starting oral min. What’s the best way to get ahold of it?

in Progress Pictures 142 upvotes 1 year ago

The post discusses the user's successful hair regrowth after 15 months of using finasteride and ketoconazole. The user is considering starting oral minoxidil, but others suggest sticking with the current treatment or trying topical minoxidil instead.

community 2500-3000 grafts. 6 months post op. 1mg finasteride daily and 5% topical minoxidil bid.

in Transplants 3177 upvotes 1 year ago

A user named "Redbone2222" shares their positive experience with a hair transplant procedure of 2500-3000 grafts, along with the use of 1mg finasteride daily and 5% topical minoxidil. They express satisfaction with the results and believe that finasteride has been more effective for them than minoxidil.

community If finasteride and dutasteride are supposed to maintain the hair that you have, then why do you go through a shedding phase?

in Finasteride/Dutasteride 18 upvotes 1 year ago

Hair loss treatments Finasteride and Dutasteride may cause shedding, but it's a good sign as miniaturized hairs are replaced by thicker ones. Shortness of breath may be experienced from Dutasteride or oral Minoxidil.

community RU users hands up I wanna hear your miracolous and horror stories.

in Treatment 44 upvotes 1 year ago

The experiences of users who have used RU58841 to treat hair loss, including both positive and negative effects. Some side effects reported include chest pain, joint pain in the hands, tinnitus, and increased heartbeat.

community 9 months progress in daily oral minoxidil 1.25mg, liquid minoxidil and oral Finasteride 1 mg

in Progress Pictures 2 years ago

Khalidsh1: Ok. I will upload one soon This user has been using a combination of oral minoxidil and finasteride, as well as topical minoxidil to treat their hair loss over the past nine months with significant progress. They have also observed thickening in other areas such as eyelashes and eyebrows.

community Comprehensive Microneedling Guide

in Microneedling 290 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.