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      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

       213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Leaving minoxidil for only 1 hour on scalp - how to maximize effectiveness?

       4 upvotes 1 year ago
      The user is trying to maximize minoxidil's effectiveness by applying it for only one hour to avoid spreading it to furniture and pets, especially cats. They experience side effects when combining minoxidil with dermarolling and are considering alternatives like oral minoxidil or microneedling.

      community Ru58841 only treatment thoughts

       4 upvotes 3 years ago
      A user plans to use RU58841 with stemoxydine and nizoral for hair loss, considering finasteride later. Others share mixed experiences with RU58841, some reporting no side effects and others experiencing issues like chest tightness, while some suggest combining it with finasteride and minoxidil for better results.

      community Antihistamines interaction with Finasteride.

       2 upvotes 4 years ago
      Stopping antihistamines may resolve neurological side effects when using finasteride. Users experienced muscle aches, headaches, and lethargy when combining the two.

      community How common are dark eye circles / wrinkles with Minoxidil?

      in Minoxidil  4 upvotes 8 years ago
      The user is concerned about potential side effects of Minoxidil, specifically dark eye circles and wrinkles, and is seeking others' experiences. They have been using finasteride and recently started Nizoral, but are hesitant to begin Minoxidil due to these concerns.

      community do any supplements actually work?

       6 upvotes 2 years ago
      A user asked if collagen or hair growth supplements made their hair thicker. Another user suggested that Vitamin D might help if deficient.

      community DS Labs SOD suppliments, anyone try them?

       4 upvotes 1 year ago
      The conversation is about trying DS Labs SOD supplements for hair loss, which contain ingredients like Genistein, B-sitosterol, and Biotin. The user is considering adding these supplements to their existing hair care routine.

      community Need some advice on Hair Transplant

       4 upvotes 5 days ago
      The conversation is about planning a hair transplant in Turkey, with advice on choosing clinics and doctors, focusing on factors like doctor involvement, clinic reputation, and realistic graft limits per session. Users recommend not exceeding 4000 grafts per session to avoid donor area damage and suggest considering two separate procedures for better graft survival.

      community 28M 5MG MIN 0.5MG DUT DAILY - DO. NOT. FEAR. THE. SHED

       116 upvotes 1 week ago
      A user shared their positive experience with hair regrowth using daily minoxidil and dutasteride, despite initial shedding. They noticed significant progress around month 4 and encouraged others to be patient with the process.

      community Applying topical Minoxidil 5% with a fine mist device vs drops?

       7 upvotes 2 weeks ago
      A user discusses using a fine mist device to apply 5% topical minoxidil for more even coverage on thinning hair compared to using drops. They are also taking oral finasteride and minoxidil, and are exploring if the mist method is as effective long-term.

      community Looking for microneedling experiences (over needling)

       4 upvotes 2 weeks ago
      The user is concerned about potentially overdoing microneedling for hair loss and is using topical finasteride and minoxidil, with underwhelming results. Other users suggest using tretinoin for better results and discuss the effectiveness of different needle lengths, recommending shorter needles.

      community My 200IQ genius master plan for dirt cheap dutasteride - can anyone see flaws to this plan?

       11 upvotes 3 weeks ago
      The conversation discusses a plan to test cheap generic Dutasteride capsules from India for authenticity using a UK drug testing service, WEDINOS, to identify reliable options for cost-effective hair loss treatment. Concerns are raised about the consistency and reliability of these generics, even if initial tests show they contain Dutasteride.

      community Vellus/miniaturized hair - when are they really too miniaturized to regrow?

       16 upvotes 4 weeks ago
      Miniaturized hair can potentially regrow unless the follicle is destroyed, with treatments like finasteride, minoxidil, and lifestyle changes playing a significant role. Some users report success with additional treatments like estrogen, ketoconazole, and derma stamping, emphasizing the importance of routine and overall health.

      community Indiamart anyone has used these ones before?

       132 upvotes 1 month ago
      The conversation discusses purchasing hair loss treatments like minoxidil and finasteride from Indiamart, with users advising to stick to reputable Indian pharmaceutical brands. Concerns about product authenticity and safety, especially regarding minoxidil's potential side effects, are also highlighted.

      community The final nail in the coffin. PP405 is confirmed JXL069.

       440 upvotes 1 month ago
      PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.

      community 2022->2026, 3.5 years Fin, no min, trans male

       81 upvotes 2 months ago
      A trans male shared his 3.5-year experience using finasteride for hair loss, noting improvements in hair density and hairline thickness without using minoxidil due to health concerns. He also uses Tołpa Torf shampoos and scalp serums, and emphasizes the importance of mental health and self-image in his journey.

      community Update on Amplifica (new drugs) and Engraft (new hair transplant technology)

       65 upvotes 2 months ago
      Amplifica is developing new molecules for hair growth, with clinical trials expected soon, while Engraft Technologies is improving FUE robotic technology to make hair transplants faster and cheaper. Users express interest in the timeline for AMP-303 and concerns about high costs and effectiveness of current treatments.

      community Other factors involved then DHT/5aR

       5 upvotes 3 months ago
      DHT is the primary cause of hair loss, but factors like diet, stress, and lifestyle can influence its severity. Treatments like finasteride and dutasteride target DHT, while maintaining overall health is also important.

      community Been on Dut since 2022, new doctor has concerns.

       15 upvotes 4 months ago
      A 31-year-old man has been using Dutasteride since 2022, alongside topical Minoxidil, with positive results and no issues. His new healthcare provider expressed concerns about long-term Dutasteride use and suggested alternatives like oral Minoxidil and Spironolactone, but the patient is hesitant to change a successful routine.