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GlossaryTransforming Growth Factor Beta Receptor 1

protein involved in cell signaling and regulating growth

Transforming Growth Factor Beta Receptor 1 (TGFBR1) is a protein that plays a crucial role in cell signaling, particularly in regulating cell growth, differentiation, and immune responses. It is part of the TGF-beta signaling pathway, which is important for maintaining tissue homeostasis and has been implicated in various conditions, including cancer, fibrosis, and alopecia.

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community The theory that explains everything. Please help me make this big!

in Research/Science 2447 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Possible topical option for preventing BDNF-related hair loss

in Research/Science 7 upvotes 1 year ago

The conversation discusses hair loss linked to BDNF-increasing nootropics like Semax and Lions Mane. Suggested topical treatments include capsaicin, beta-glucan, and ginseng to counteract TGF-B activation.

community Taurine supplements work for hair growth?

in Product 8 upvotes 7 months ago

The conversation discusses taurine supplements for hair growth, highlighting their potential to reduce DHT and improve hair health. A user comments that people often try alternatives to finasteride.

community SAFFLOWER OIL good alternative for Minoxidil?

in Treatment 1 upvotes 4 years ago

Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 669 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community ladies and gentlmen, vitamin E is your hair follicles second best friend

in Treatment 51 upvotes 2 years ago

Vitamin E is suggested as beneficial for hair follicles. Some users question the dosage and effectiveness, while others share positive experiences with vitamins.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community Please stop looking for a natural way to stop your hairloss

in Chat 247 upvotes 2 years ago

There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

community 5 months of nuking T, 2 months of minoxidil

in Transgender 485 upvotes 3 months ago

The user transitioned from finasteride to Cyproterone and started using Minoxidil, resulting in healthier hair and regrowth. They plan to wean off Minoxidil in a year, depending on regrowth.

community Oral min 2.5mg daily 2 month update 🦍

in Satire 826 upvotes 1 year ago

The post and conversation are about the user's experience with oral minoxidil for hair loss. Some users noticed increased hair density, while others experienced unwanted hair growth in different areas of the body.

community Homemade topical spironolactone

in Research/Science 26 upvotes 2 years ago

The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

community Should I Add Dermarolling to My Hair Regrowth Routine?

in Microneedling 37 upvotes 4 months ago

An 18-year-old using Minoxidil 2% for hair loss is considering adding dermarolling to their routine. Replies suggest adding finasteride, using a dermastamp, and microneedling, with positive experiences shared.

community Minoxidil&Finasteride 7 months progress

in Progress Pictures 936 upvotes 1 year ago

A user shared their 7-month progress using Minoxidil and Finasteride for hair loss, which significantly reversed their aging appearance. They applied Minoxidil twice daily, took 1mg Finasteride once daily, micro-needled weekly, maintained a high protein diet with vitamins and biotin, and recommended a balanced lifestyle for best results.

community Redensyl Megathread !!!!

44 upvotes 5 years ago

Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.

community When you're balding is it an absolute traumatic period of your life or do some people not care as much?

in Chat 89 upvotes 4 months ago

Balding can be traumatic for many, affecting self-esteem and social interactions, while others accept it more easily. Treatments mentioned include finasteride, minoxidil, and RU58841.

community 4 Months on 1mg Finasteride, 0.25mm Derma Roller with Rosemary Oil + Biotin Pills. 31 Years Old. (After & Before Pics)

in Progress Pictures 192 upvotes 11 months ago

A user shared progress pictures after 4 months of using 1mg finasteride, a 0.25mm derma roller with rosemary oil, and biotin pills for hair loss. They reported being very happy with the results.

community Minoxidil seems logistically impossible and impractical to use

in Minoxidil 136 upvotes 1 year ago

The post discusses concerns about the practicality of using Minoxidil foam for hair loss, including the frequency of application, preparation, coverage area, and drying time. Responses suggest that missing a dose isn't detrimental, it can be applied once a day, it works on all hair areas, and it doesn't need to be perfectly dry before application.

community Progress over one year. June 2022 > June 2023 (fin+min)

in Progress Pictures 685 upvotes 1 year ago

A user's one-year progress in hair loss treatment using finasteride and minoxidil. The user shared their experience and advice, including adjusting the amount of sprays used based on individual needs and the importance of patience and positivity in the process.

community Fin raised my estrogen but also testosterone?

in Finasteride/Dutasteride 17 upvotes 10 months ago

A user experienced initial side effects from finasteride, including erectile dysfunction and emotional changes, but later noticed increased muscle mass and assertiveness. Hormonal tests showed elevated estrogen and prolactin levels, which slightly decreased over time; the user plans lifestyle changes to see if they help.

community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 45 upvotes 6 months ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Does pyri/kx826 degrade in exposure to bathroom light?

in Treatment 5 upvotes 3 months ago

The conversation discusses concerns about RU58841 degrading when exposed to light and transferring pyri to a dark glass bottle to prevent this. The user keeps the pyri out for only two minutes before storing it in a dark place.

community How long is topical Fin “active” on the scalp?

in Finasteride/Dutasteride 6 upvotes 1 year ago

Topical finasteride remains active on the scalp for a certain period after application, and there is concern about the safety of touching the hair and transferring the medication to the fingers.

community Almost exactly a year apart. Trying to let it grow and blend a bit. 41 years old.

in Progress Pictures 837 upvotes 9 months ago

A user shared their one-year progress using Dutasteride, oral and topical Minoxidil, RU58841, and microneedling tools from Amazon, and credits learning from top posters on the forum. Other users discuss the effectiveness of the treatments, affordability, and reflect on the benefits of starting treatment early.

community Amazon will start selling cheap Finasteride

in Finasteride/Dutasteride 706 upvotes 1 month ago

Amazon will sell affordable finasteride, with users comparing prices from various sources like Costco and Mark Cuban's pharmacy. Some users also discuss the benefits of dutasteride for hair thickness.

community My 4th update nearing 9 months now. Min 5% liquid twice daily, Fin 1mg daily, microneedling 1.5mm weekly

in Progress Pictures 434 upvotes 9 months ago

A user nearing 9 months of hair loss treatment reports using Minoxidil 5% liquid twice daily, Finasteride 1mg daily, and microneedling with a 1.5mm roller weekly. They also take Vitamin D, B7, Zinc, and considered but did not use Dutasteride or Ketoconazole shampoo.

community Stop supporting Keeps and Roman, they’re price gouging you

in Finasteride/Dutasteride 360 upvotes 1 year ago

The post discusses the high cost of hair loss treatments from companies like Keeps and Roman, and suggests cheaper alternatives like GoodRx. Users share their experiences with different providers, costs, and methods of obtaining finasteride, a common hair loss treatment.

community All in restoration Hair transplant from Dr Serkan in Turkey + topical fin/min Viviscal,biotin,sulfate free shampoo and Nizoral…very happy with results

in Progress Pictures 93 upvotes 2 years ago

A successful hair transplant with 3100 grafts combined with topical finasteride, minoxidil, Viviscal, biotin, sulfate free shampoo and Nizoral. People in the conversation talk about how the results look perfect and discuss the number of grafts and cost involved.

community Been on Min and Fin for Years and I am Devastated.

in Treatment 64 upvotes 2 years ago

Guyman567 has been using oral finasteride and topical minoxidil for years but continues to experience hair loss and thinning, which has affected his confidence. He has tried various treatments including topical finasteride, microneedling, and vitamins, and is considering a hair transplant but is concerned about ongoing hair loss.

community Not all generic medications are made equal. Some work great, some weaker, and some are dangerous. What Pharmaceutical makes your current/past generic Finasteride?

in Finasteride/Dutasteride 7 upvotes 3 years ago

The conversation discusses the variability in effectiveness and safety of generic finasteride from different manufacturers, with some generics potentially containing impurities. Users shared their experiences with various brands, questioning if different brands affect hair loss treatment outcomes.