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GlossaryTransepidermal Water Loss

water evaporates from the skin's surface, indicating barrier function

Transepidermal Water Loss (TEWL) refers to the process by which water passes from the inside of the body through the epidermis (the outermost layer of the skin) and evaporates into the environment. It is a key indicator of the skin's barrier function; higher TEWL values suggest a compromised skin barrier, which can lead to dryness, irritation, and conditions like eczema.

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community Has anybody tried retinol (not Retin A aka tretinoin) combined with minoxidil?

in Treatment 20 upvotes 2 years ago

The conversation is about someone who had success using retinol with minoxidil for hair growth, but experienced shedding with Retin A (tretinoin). They are asking if others have tried retinol with minoxidil and what their results were.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 451 upvotes 4 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community Dutasteride SAVES your hair follicles: MAJOR BS on people who say it destroyed their hair permanently.

in Finasteride/Dutasteride 159 upvotes 9 months ago

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

community 6 months progress no fin 27m topical foam minox

in Progress Pictures 250 upvotes 10 months ago

The user has been using 5% Minoxidil foam twice daily, microneedling every two weeks, and Nizoral 2% shampoo weekly for hair loss treatment. They've seen improvements in their hairline and eyelashes, and are considering adding finasteride to their regimen.

community Regrowing my hair/line without Min or Fin September (update) mechanical stimulation

in Finasteride 24 upvotes 6 years ago

The user regrew their hairline using mechanical stimulation, including a 1.5mm derma roller weekly, daily scalp massages, and other treatments like Nizoral, zinc pyrithione, fish oil, and Lipogaine The Big 5. They did not use Minoxidil or finasteride.

community Trans: Do I need to use Finnasteride?

in Transgender 11 months ago

A transgender individual is starting spironolactone and estradiol for hormone replacement therapy (HRT) and is considering adding finasteride to help with hair loss. They are also planning to use minoxidil and microneedle, but are unsure if they need to use another anti-androgen or more aggressive treatments. A respondent advises against using pyri and suggests waiting to see if the HRT alone is sufficient before becoming dependent on minoxidil.

community Oral vs Topical Finasteride for Trans Women

in Transgender 1 month ago

A user is using a Finoxidil topical spray and is curious if oral Finasteride would be more effective, considering they are already on a DHT blocker called Cyproterone. They are concerned about the potential impact of oral Finasteride on their transition.

community Comparing the effect of T suppression and DHT suppression

in Transgender 52 upvotes 2 months ago

Trans women discuss using finasteride and dutasteride for hair loss and whether to continue after testosterone suppression. One user reduced dutasteride dosage after achieving undetectable testosterone levels.

community Why is my crown still thinning? (MTF 4+ years/Fin 3+ years/Microneedling 1mo)

in Transgender 3 upvotes 1 year ago

Trans woman experiencing thinning hair despite low testosterone and finasteride use seeks possible causes and solutions. Current treatments include finasteride, spironolactone, estradiol, vitamins, and microneedling; minoxidil not tried due to concerns about dependence and side effects.

community Possible causes for crown/top of head thinning even while on a “nuclear” stack? (MTF + fin + microneedling)

in What should I do? 2 upvotes 1 year ago

Trans woman experiences hair thinning despite low testosterone and treatments like finasteride and microneedling. Possible causes discussed include past eating disorder and current stack of medications and supplements.

community Don't give up! 9 months on Minoxidil

in Progress Pictures 399 upvotes 4 months ago

A trans man shared progress pictures showing significant hair regrowth after 9 months on oral Minoxidil and 1.5 years on finasteride. He encourages others to stick with their treatments despite initial setbacks.

community Will vellus hairs in thinning areas go terminal if you go all out?

in Transgender 9 upvotes 9 months ago

A trans woman is using finasteride, minoxidil, microneedling, and HRT to address hair loss, with noticeable improvement in hairline shape and presence of vellus hairs. She is considering hair transplants if these treatments don't yield desired results within a year or two.

community How well can HRT reduce scalp tension?

in Transgender 6 upvotes 1 year ago

A trans woman is curious about the impact of HRT on hair regrowth and scalp tension. Her current regimen includes finasteride, spironolactone, estradiol, ketoconazole, vitamin D, iron, and plans to add oral minoxidil and restart derma rolling.

community 5 months MTF HRT no min/fin/dut

in Progress Pictures 31 upvotes 2 months ago

A 22-year-old trans woman has been on 6mg estradiol enanthate for five months. She reports thicker and healthier hair but not much regrowth yet.

community hair loss treatment alternatives and ideas to improve gain

in Treatment 3 upvotes 1 year ago

The post discusses using finasteride, minoxidil, ketoconazole, and a dermaroller for hair loss, along with spearmint capsules, pueraria mirifica, saw palmetto, biotin, and vitamins. The user is also considering microdosing finasteride with trans treatment and mentions the potential of herbal enemas and hair systems.

community 5% Minoxidil after 4 months - started with twice a day but went down to once because I kept forgetting in the morning. Really happy with how it is going!

in Progress Pictures 438 upvotes 1 year ago

The conclusion of the conversation is that the user started using 5% Minoxidil for hair loss and is happy with the progress. They also mentioned being trans and coming off testosterone, which they believe will help prevent further hair loss. Some users suggested using finasteride as well.

community People who used cyproterone for hair loss

in Treatment 2 upvotes 11 months ago

The conversation discusses the use of 12.5mg cyproterone every other day for hair loss. There's a concern about reducing testosterone potentially increasing DHT and negatively affecting hair.

community I’ve been using topical finasteride + minoxidil + tretinoin + caffeine for three months now and was just wondering will these smaller hairs eventually grow and thicken to keep up with the length of my others hairs? Clearly, my other hairs are much thicker and longer. Btw, this is near the temple. Ty

in Is this regrowth? 7 upvotes 1 year ago

The conversation is about someone using topical finasteride, minoxidil, tretinoin, and caffeine for hair regrowth, particularly near the temple area. They are asking if the new, smaller hairs will grow and thicken to match their existing hair.

community 10 Months of Nuclear Stack [Dut, Min, Keto + Estradiol & Spironolactone (MtF HRT)] -- Does it need more time or does it need a transplant?

in Progress Pictures 6 upvotes 2 weeks ago

The post discusses using a combination of Dutasteride, Minoxidil, Ketoconazole, Estradiol, and Spironolactone for hair regrowth. Users suggest it needs more time and possibly a transplant, with some sharing personal experiences and side effects of similar treatments.

community 25-31 recovery makes my hair almost unmanageable.

in Progress Pictures 17 upvotes 4 months ago

A user shared their hair recovery progress from ages 25-31, attributing success to quitting smoking, minoxidil, microneedling, and hormone therapy. They also mentioned being transgender and using hormone therapy.

community Going to a cosmetic derm soon. What should I ask for?

in Female 3 upvotes 1 year ago

Female, 28, losing hair since 17, using 200mg Spiro. Tried Minoxidil and ketoconazole with limited success, considering oral minox and seeking alternative treatments from cosmetic dermatologist.

community 5 months on Spiro and 6 weeks on oral Monoxidil. Beyond thrilled with the results so far

in Female 190 upvotes 4 years ago

Treatments for hair loss, specifically the use of Spironolactone (Spiro) and oral Minoxidil, as well as Finasteride and RU58841.

community 4 months (+ growing hair out) on min/fin/niz/dermaroll/estrogen/vitamins

in Progress Pictures 86 upvotes 10 months ago

The user is using oral finasteride, topical minoxidil, Nizoral, dermarolling, a hair thickening conditioner, and hair vitamins for hair loss treatment. They stopped taking testosterone due to medical reasons and are now technically on estrogen, but it's unclear if this impacts their hair growth.

community 11 Months Pantostin / 3 Months 25mg CPA

in Is this regrowth? 17 upvotes 1 year ago

The user is asking for opinions on whether their hair growth is due to Pantostin and hormone treatments. One commenter confirms regrowth and asks about the hormone treatments.

community What factors cause more regrowth for MTF people with hormone replacement therapy?

in Transgender 6 upvotes 1 year ago

Hair regrowth in transfems is more effective due to hormonal changes, specifically estrogen, which keeps hair in growth phase longer. Treatments mentioned include anti-androgens, sex hormones, and DHT blockers like finasteride.

community spironolactone vs bicalutamide What is the difference between them for androgenic alopecia for women?

in Female 7 upvotes 2 years ago

Hair loss discussion involves spironolactone and bicalutamide for women's androgenic alopecia. Focus on effectiveness and side effects.

community Experience with Spironolactone?

in Female 7 upvotes 2 years ago

Spudlady asks about experiences with spironolactone for hair loss. She has lost hair due to stress and seeks ways to stop shedding.

community 25M - 4 month progress on min + fin

in Progress Pictures 258 upvotes 1 month ago

A 25-year-old shared his 4-month progress using oral minoxidil, oral finasteride, a 1mm dermastamp, Nizoral, and upgraded shampoo and conditioner. He feels he sees some regrowth, though some commenters attribute the change to a different hairstyle.

community HRT is literal black magic. Fin 1 mg/day @ 4 years, min 2x/day @ 3 years, Estradiol 4mg/day @ 3.5 months, and Spironolactone 100mg/day @ 3.5 months (estra & spiro are medicines you should likely not take if you are a cis man)

in Progress Pictures 118 upvotes 1 month ago

User shared progress on hair regrowth using Fin 1 mg/day for 4 years, Min 2x/day for 3 years, Estradiol 4mg/day, and Spironolactone 100mg/day for 3.5 months. They noted significant hairline recovery and advised against HRT for cis men due to feminizing effects.

community Duta/Minoxidill/some microneedling

in Progress Pictures 86 upvotes 2 months ago

A user shared progress pictures showing significant hair growth over 3.5 months using Dutasteride, Minoxidil, and microneedling. They are pleased with the results but unsure how to style their growing hair.