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      community Why is scalp DHT suppression lower than systemic?

      in Finasteride/Dutasteride  11 upvotes 1 year ago
      Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

      community Quit finasteride after 15+ years

       972 upvotes 1 year ago
      A user stopped finasteride after 15 years due to severe side effects, which improved after quitting. They maintained most of their hair and are considering alternatives like topical treatments or RU58841.

      community Influencers and their recommendations

      in Satire  6 upvotes 10 months ago
      Bryan Johnson uses Dutasteride, Latanoprost, Minoxidil with Tretinoin, and other unproven treatments, while Derek uses Finasteride, Minoxidil, Nizoral, RU58841, and Castor Oil. Kevin uses Finasteride, Minoxidil, RU58841, and Alfatradiol, but is against Nizoral and microneedling, preferring Tretinoin for absorption.

      community If you rank hairloss treatments fin,min,dut are the top 3, what's next?

       40 upvotes 10 months ago
      Dutasteride, finasteride, and minoxidil are considered the top hair loss treatments. Other suggested treatments include Nizoral shampoo, tretinoin, pyrilutamide, zinc, biotin, and low light laser therapy, though opinions on their effectiveness vary.

      community The most nuclear stack possible

       45 upvotes 1 year ago
      A user humorously suggests an extreme hair loss treatment regimen involving multiple medications and therapies, including Dutasteride, Minoxidil, RU58841, and others, claiming it would prevent hair loss but with potential side effects like gynecomastia. The conversation highlights concerns about safety, side effects, and the effectiveness of such a comprehensive approach.

      community Losing the gains and frontline of battle

      in Progress Pictures  59 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically the use of dutasteride, finasteride, and other methods like PRP, laser, and mesotherapy. Despite these treatments, the user is experiencing hair loss, and others suggest consulting a dermatologist, considering alternative treatments, and addressing potential scalp inflammation.

      community 25 years on Finasteride and it's not working anymore.

       324 upvotes 6 months ago
      A 47-year-old has been using finasteride for 25 years for hair loss, but it's less effective now. Suggestions include switching to dutasteride, stopping anastrozole, and trying minoxidil, microneedling, and possibly TRT.

      community ~6-7 month progress. November 2025 - May 2026

       44 upvotes 4 months ago
      The user experienced significant hair regrowth using finasteride alone over 6-7 months, despite initial side effects like reduced sexual desire and acne. They are considering reducing the dosage to manage side effects and have also used ketoconazole shampoo weekly.

      community Topical melatonin spray to reduce hair shedding recommends?

       1 upvotes 10 months ago
      The user has been using topical melatonin spray with finasteride and dutasteride to reduce hair shedding but dislikes the lavender scent of their current spray. They are seeking recommendations for a scentless or better-smelling melatonin spray.

      community Topical melatonin shows some promise.

       4 upvotes 10 years ago
      Topical melatonin shows promise for increasing hair density with minimal side effects. The user is transitioning from oral finasteride to a compounded minoxidil and finasteride solution and considering melatonin and bimatoprost as additional treatments.

      community EU topical melatonin recommendations?

       7 upvotes 8 months ago
      The conversation discusses recommendations for using topical melatonin for hair loss treatment. It also mentions Minoxidil, finasteride, and RU58841 as other treatments.

      community Anyone tried topical melatonin?

      in Treatment  4 upvotes 2 years ago
      The conversation is about using topical melatonin for hair retention and its potential effectiveness alongside minoxidil. The user explicitly does not want advice about finasteride.

      community best way make topical melatonin solution

       6 upvotes 2 years ago
      A user wants to try melatonin for hair loss by mixing melatonin powder with a topical oil serum. They are asking if this mixture is possible and effective.

      community How does one use topical melatonin?

       3 upvotes 2 years ago
      The conversation is about using melatonin for hair loss treatment, questioning whether to mix oral melatonin with minoxidil or to apply a melatonin tincture directly to the scalp.

      community How to make topical melatonin?

      in Treatment  1 upvotes 2 years ago
      The conversation is about creating a topical melatonin treatment for hair loss. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.

      community How are you using topical melatonin?

      in Treatment  1 upvotes 2 years ago
      The user is experimenting with topical melatonin for hair loss by dissolving melatonin tablets in a solution, but is having trouble with dissolution and is curious about others' methods of application and any effects on energy levels. They mention considering mixing with minoxidil but have not done so, and suggest that melatonin is best used at night.

      community Okay to add melatonin powder to the topical finasteride solution?

       15 upvotes 3 years ago
      The conversation discusses adding melatonin powder to a topical finasteride solution for hair loss, with one reply suggesting that melatonin may promote faster hair growth but advising against mixing it directly into the solution due to potential instability.

      community How long have you tried topical melatonin?

       4 upvotes 2 years ago
      The conversation is about the effectiveness of topical melatonin for hair loss, asking for details on dosage, frequency, duration of use, results, and brand information. An update includes a skeptical view on the studies regarding melatonin's effectiveness.

      community Has anyone created their own topical melatonin solution?

       4 upvotes 3 years ago
      The conversation discusses creating a topical melatonin solution for hair loss, with challenges in dissolving melatonin pills due to additives. Suggestions include using melatonin powder mixed with ethanol and glycerin.

      community Melatonin for hair loss

       4 upvotes 5 years ago
      Topical melatonin may help with inflammation-induced hair loss. The user plans to try it and share results.

      community Diluting Melatonin Sublingual Spray

      in Treatment  2 upvotes 2 years ago
      A user wants to dilute a melatonin sublingual spray to 0.0033% for use as a topical hair loss treatment. They ask if distilled water can be used for dilution and how much is needed for stability over months.

      community Topical Fin 0.1% 5% min 7 months review

       5 upvotes 4 years ago
      Using topical finasteride 0.1%, minoxidil 5%, and melatonin for 7 months reduced hair loss significantly, with increased libido and decreased stress tolerance. The user applies the solution once daily, uses nizoral twice weekly, and takes vitamin D and ZMA supplements.