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      community How many have experimented with ru58841 and topical GHK-CU?

       9 upvotes 1 month ago
      RU58841 and topical GHK-CU are used together for hair loss, with RU58841 reducing shedding and GHK-CU improving scalp health. Users report noticeable hair growth and improved hair quality within weeks, especially when used consistently.

      community Losing hairs on aggressive treatment.

      in Transgender  2 upvotes 3 months ago
      The user is experiencing hair loss despite using estradiol, bicalutamide, dutasteride, and topical minoxidil. They stopped minoxidil temporarily, which worsened their condition, and are considering oral minoxidil but are concerned about side effects and cost.

      community Does RU work? I see people buying it and reporting success, but if so why was it discontinued?

      in Treatment  3 upvotes 1 year ago
      RU58841 is a controversial hair loss treatment with mixed reviews; some users report success, often in combination with other treatments like finasteride or minoxidil, while others experience side effects like chest pain. The treatment's discontinuation is speculated to be due to patent expiration and lack of profitability, despite some users continuing to use it as part of a broader regimen.

      community How to minimize RU going systemic?

       5 upvotes 4 years ago
      An 18-year-old is considering using RU58841 for aggressive hair loss and is also thinking about taking creatine. Users suggest avoiding creatine due to its potential to increase DHT and recommend using topical finasteride instead.

      community Losing the genetic lottery - venting

      in Chat  67 upvotes 4 months ago
      The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

      community So what is the most compelling current research on a cure?

       4 upvotes 11 years ago
      Setipiprant, a PGD2 inhibitor, and RepliCel, a cell transplantation technology, are being explored as potential hair loss treatments. Current mainstream treatments like Minoxidil and Finasteride have limitations due to side effects and efficacy.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community any females on RU58841/minoxidil 2.5%?

       6 upvotes 5 years ago
      A female user is considering using RU58841 with minoxidil 2.5% to reduce side effects like facial hair from minoxidil 5%, while also using copper peptides and a hair serum. Other users discuss alternative treatments like spironolactone, alfatradiol, and the side effects of finasteride.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community RU-58841 without finassteride?

      in Treatment  6 upvotes 1 year ago
      RU58841 is used without finasteride by some due to side effects, with mixed results. Users report combining RU58841 with minoxidil and adjusting finasteride doses to manage hair loss.

      community Clascoterone - what we have right now

       24 upvotes 6 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community ru58841: Anyone have experience with this?

      in Product  1 upvotes 1 year ago
      The conversation is about hair loss treatments, specifically discussing RU58841, with concerns about its safety and lack of research. Alternatives like finasteride, dutasteride, and minoxidil are mentioned, with some users sharing personal experiences and side effects.

      community Clascoterone phase 3 results are out!

       80 upvotes 9 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 8 months ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community Is RU58841 really a game changer ?

       30 upvotes 4 years ago
      Topical finasteride and minoxidil show some hair regrowth, but hair loss persists. RU58841 is considered effective by some users but is not well-tested, with potential side effects; it may be used alongside finasteride for better results.

      community European release of clascoterone

       13 upvotes 4 months ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Clascoterone full results 2026

       7 upvotes 2 weeks ago
      Clascoterone results are anticipated to be released in fall 2026, possibly at the EADV conference. Users express skepticism and humor about the release date.

      community RU58841 Permanently Fixed Balding In Unexpected Way.

      in Satire  123 upvotes 10 months ago
      The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 1 year ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community Pp405 trials question - 2a/2b,

       6 upvotes 10 months ago
      PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

      community Transplant Candidate? (26, Male)

       40 upvotes 7 months ago
      A 26-year-old male considering a hair transplant is using topical finasteride and minoxidil, planning to start feminizing hormone replacement therapy (HRT) with estrogen and spironolactone. Many suggest waiting to see the effects of HRT, which may significantly regrow hair, before deciding on a transplant, and recommend adding microneedling and possibly switching to oral treatments for better results.

      community RU58841 + Minoxidil at 19 Years

      in Treatment  1 upvotes 6 months ago
      A 19-year-old is experiencing hair thinning and considering using RU58841 alongside minoxidil, which initially worked but lost effectiveness. Others advise caution, suggesting safer alternatives like topical finasteride and consulting a doctor before using unapproved treatments like RU58841.