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GlossaryTargeted Therapies

treatments that specifically target disease-causing molecules or cells

Targeted therapies, also known as precision medicine, are treatments designed to specifically target and attack the molecular and cellular mechanisms driving a disease, such as cancer or autoimmune conditions. Unlike traditional treatments that affect all rapidly dividing cells, targeted therapies aim to minimize damage to normal cells by focusing on specific genetic mutations or proteins involved in the disease process.

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community I believe CRISPR-on & CRISPR-off is an ultimate CURE for baldness, unlike Hair Cloning or hair loss treatments.

in Research/Science 22 upvotes 3 years ago

The conversation discusses CRISPR-on & CRISPR-off as a potential cure for baldness, contrasting it with hair cloning and other treatments like Minoxidil, finasteride, and RU58841. It also mentions the potential of mRNA for gene expression control and the prioritization of gene editing for severe genetic conditions.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 1 month ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 3 weeks ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 5 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Male pattern baldness, and mental health

in Finasteride/Dutasteride 323 upvotes 9 months ago

A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

community What was your “f*ck I’m balding” story?

in Chat 178 upvotes 1 year ago

User noticed thinning hair at 18-19, started finasteride at 22 and minoxidil at 24, with positive results. Others shared hair loss experiences and treatments, including finasteride, minoxidil, and hair transplants.

community Grey Market GT20029 and Frequency of Application

in Product 10 upvotes 6 months ago

The conversation is about the potential release of GT20029 on the grey market and concerns about its safety and authenticity. One user advises waiting for the official release by Kintor.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 8 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Solving Hair Loss with Research at MIT

in Research/Science 592 upvotes 2 weeks ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community The story of RU58841/ PSK3841

in Research 622 upvotes 2 months ago

RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 2 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community GT20029 Anageninc Market Availability

in Research/Science 165 upvotes 1 year ago

The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 446 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community My microneedling journey (no min, fin, etc)

in Microneedling 187 upvotes 1 month ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community Anti androgen shed all over scalp

in Treatment 3 upvotes 1 year ago

The user is experiencing intense hair shedding all over the scalp after applying pyrilutamide to the hairline and taking oral castor oil. They are also using topical finasteride and latanoprost, but are unsure which treatment is causing the shedding.

community Serum DHT CAN'T cause hair loss. Sebum DHT is a better measurement.

in Research/Science 19 upvotes 1 month ago

Serum DHT is mostly inactive; sebum DHT is a better measure for hair loss. Users discuss using finasteride, dutasteride, and topical treatments like KX826 and RU58841 for better scalp DHT suppression.

community When is GT20029 going to come out?

in Research/Science 34 upvotes 1 month ago

The conversation discusses the anticipation and skepticism around the release of GT20029 for hair loss treatment. The original poster has been using Finasteride and Minoxidil but is hopeful for GT20029, while others express doubts about its timely release and suggest alternatives like KX826 and hair transplants.

community So whats the consensus for Microneedling Routines?

in Microneedling 7 upvotes 4 months ago

Optimal microneedling routine is 1.25mm once a week with Dr Pen 36 needles. Applying Minoxidil right after microneedling may increase systemic absorption risk.

community My one year results on fin/min.

in Update 246 upvotes 4 months ago

A user shared their one-year results using finasteride and minoxidil for hair loss, showing noticeable improvement. They started seeing results at six months, using 1ml liquid twice a day and a pill once a day.

community Best way to apply liquid topicals (minoxidil, RU58841 solution, etc) especially for thick or long hair, diffuse thinning

in Treatment 3 upvotes 1 week ago

Using a blunt tip syringe is an effective method for applying liquid topicals like minoxidil and RU58841, especially for those with thick or long hair experiencing diffuse thinning. The user found significant hair regrowth and increased density after using these topicals for less than three months.

community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

in Treatment 117 upvotes 1 month ago

Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.

community Is injections with dermapen possible?

in Microneedling 6 upvotes 4 months ago

A user is considering using a dermapen with liquid solutions like minoxidil for hair loss as a cost-effective alternative to mesotherapy. They seek advice on the effectiveness and experience with such devices.

community A little over a year of gains. Have hope, guys

in Journals / Progress Pictures 249 upvotes 5 months ago

Significant hair regrowth was achieved using a combination of Finasteride, Minoxidil, Dutasteride, and RU58841. The user switched from Finasteride to Dutasteride and added RU58841 for better results.

community Breaking hair loss news! GT20029 is a resounding success!

in Product 138 upvotes 6 months ago

GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.

community 21m - Just over 2 months on 1mg fin, 5% min (once a day), Keto, Biotin supplements

in Progress Pictures 22 upvotes 6 months ago

A 21-year-old male has been using 1mg finasteride, 5% minoxidil once daily, ketoconazole, and biotin supplements for over two months and is seeing new hair growth on his forehead, but is unsure if the growth will continue or shed.

community Expectations control for SCUBE3

in Research/Science 20 upvotes 7 months ago

SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

community M46 - 3 week progress on HIMS serum

in Progress Pictures 12 upvotes 7 months ago

A 46-year-old male shared his 3-week progress using HIMS serum with Finasteride 0.3% and Minoxidil 6%, showing improvement without noticeable shedding. His routine includes vitamins, a healthy diet, and specific hair care practices like microneedling and using caffeine solution.

community Will minoxidil not work if there’s too much DHT present in the scalp?

in Minoxidil 5 upvotes 8 months ago

The user has been using topical finasteride and minoxidil for five months with little progress and is considering oral dutasteride to lower DHT levels, questioning if minoxidil is more effective with reduced DHT. They also use microneedling and tretinoin in their treatment routine.

community Tried addressing DHT and regrowth, wanting to try additional path

in Research/Science 4 upvotes 10 months ago

The user is addressing hair loss with finasteride, dutasteride, oral and topical minoxidil, dermarolling, and shampoos. They are considering adding essential oils to improve circulation.