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      community Does anyone know the chemical formula for pelage pp405?

       15 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community Don't use PP405 from everychem. it is likely fake.

       63 upvotes 1 year ago
      PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.

      community 20MTF Results on the crown from 1 year on estrogen injections

       468 upvotes 6 months ago
      Estrogen injections significantly improved hair growth, particularly on the crown, after stopping finasteride. Monotherapy with estrogen led to hairline improvement, but also caused sterility and potential feminization effects.

      community DUPA, Non Responders and Connective Tissue Disorders

       8 upvotes 1 year ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community Do hair follicles dies or are dormant ?

      in Finasteride/Dutasteride  92 upvotes 1 year ago
      Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

      community One year on dutasteride and minoxidil. In depth review below

      in Progress Pictures  44 upvotes 1 month ago
      A 22-year-old has been using oral dutasteride and minoxidil for a year to prevent hair loss, experiencing some thinning at the temples but maintaining a full head of hair. The user increased the dosage after consulting a dermatologist and is considering adding ketoconazole shampoo for additional scalp DHT suppression.

      community What has the evidence been on side effects with CB?

       4 upvotes 6 years ago
      Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.

      community Peptides that Stop Hair Loss? | In-depth Literature Review Video

       76 upvotes 2 years ago
      Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

      community Why I never used Fin, Min, Or Dut and Rebuilt My Scalp From the Ground Up (Real Results)

      in Treatment 3 weeks ago
      The conversation discusses a natural approach to hair loss treatment, emphasizing a diet rich in whole foods, supplements like Saw Palmetto, Zinc, and Pumpkin Seed, and mechanical scalp stimulation with microneedling, avoiding pharmaceuticals like finasteride, minoxidil, and dutasteride. The user claims success with this holistic method, reporting new hair growth and improved overall health.

      community Losing progress on 1 mg Fin and 5 mg minoxidil

      in Progress Pictures  73 upvotes 5 months ago
      The user experienced initial hair regrowth with 1 mg finasteride and 5 mg minoxidil but began shedding after 4-5 months, which others suggest is common and may lead to thicker regrowth. Users recommend patience, as results can take up to 12-24 months, and suggest considering specialized clinics for hairline design if unsatisfied with medication alone.

      community Before and after of 20 months of fin and min

      in Progress Pictures  125 upvotes 7 months ago
      The user experienced worsening hair thinning despite using finasteride, minoxidil, and ketoconazole shampoo, and switched to dutasteride five months ago. They are considering adding tretinoin and microneedling to their routine for better results.

      community [22m] Is it time for a transplant?

      in Progress Pictures  56 upvotes 1 year ago
      A 22-year-old is experiencing aggressive hair loss despite using minoxidil and finasteride and is considering a hair transplant but lacks funds. The discussion includes advice on treatments like dutasteride, microneedling, and lifestyle changes, with mixed opinions on the timing and effectiveness of a transplant at a young age.

      community its been over 6 months, feeling like a new man

      in Progress Pictures  292 upvotes 1 year ago
      A 20-year-old male experienced significant hair regrowth and transformation in under 7 months using oral minoxidil and finasteride. His hair became curlier, darker, and denser, leading to a dramatic change in appearance.

      community 5 years apart on 1.25mg finasteride and 5mg oral minoxidil daily

       3325 upvotes 11 months ago
      Significant hair improvement was achieved using 1.25mg finasteride and 5mg oral minoxidil daily, with no side effects. The user increased the minoxidil dosage to 7.5mg after noticing minor thinning and plans to continue the routine.

      community Jxl069 (pp405 api) week 8 update

       205 upvotes 1 year ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Hair Loss Inflammation Prevention Stack

       48 upvotes 1 year ago
      The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

      community Why I’m treating my hair loss instead of shaving my head

       70 upvotes 1 month ago
      The conversation discusses hair loss treatments, with the original poster using finasteride, minoxidil, red light therapy, and Nizoral shampoo, and planning a hair transplant. The discussion emphasizes the emotional impact of hair loss and the importance of mental health, while sharing personal experiences and treatment outcomes.

      community 9 months of treatment as an aggressive diffuse thinner

       67 upvotes 4 months ago
      The user has been using oral minoxidil, dutasteride, RU58841, and other treatments for hair loss over nine months, seeing some improvement in hair thickness and crown volume but continued thinning at the hairline. They plan to continue treatment for another nine months despite being sensitive to DHT fluctuations and are considering increasing dosages or other options like a hair transplant.

      community Been on min+fin for 2 years, only gotten worse. B/A pics included

      in Chat  88 upvotes 7 months ago
      The user experienced worsening hair loss despite using finasteride and topical minoxidil for two years and is considering oral minoxidil and dutasteride. Suggestions include microneedling, stress management, and alternative treatments like topical finasteride or ketoconazole shampoo.