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GlossaryDermal Stem Cells

specialized skin cells that regenerate and repair dermal tissue

Dermal Stem Cells, also known as dermal progenitor cells, are specialized cells found in the skin's dermis layer that have the ability to self-renew and differentiate into various cell types, including fibroblasts, which are crucial for wound healing and collagen production. These cells play a significant role in skin regeneration and repair, making them a key focus in research on anti-aging treatments and therapies for skin-related conditions.

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community Anyone Try Microneedling with Exosomes/AAPE?

Additional-Ask-9597 in Microneedling 2 upvotes 2 years ago

User asks where to purchase exosomes/AAPE for microneedling hair loss treatment. Links to research on hair regeneration therapy, stem cell therapy, exosome therapy, and dermal exosomes provided.

community Dr. Tsuji and Riken to make important announcement on their hair cloning cure on Feb 10th.

roystreetcoffee in Update 56 upvotes 4 years ago

Dr. Tsuji and Riken announced a hair cloning cure with a 98.9% success rate, expected to be released in 10 years. Users expressed hope and skepticism about the affordability and timeline of the treatment.

community Hair loss causes are still a myth.

dannxFox in Chat 16 upvotes 3 years ago

The conversation discusses the complexity of hair loss causes, suggesting that DHT sensitivity alone doesn't fully explain it. Treatments mentioned include finasteride and dutasteride.

community How does it feel to microneedle at 0.3mm?

Mobile_Ad_9937 in Microneedling 17 upvotes 9 months ago

The conversation discusses microneedling for hair loss, with one user trying 0.3mm daily without feeling pain and questioning its effectiveness. Another user suggests that 0.3mm is too shallow and recommends 0.5mm twice a week or 0.75mm once a week for hair growth.

community New drug for hair loss announced by Amplifica

wrassman in Research/Science 161 upvotes 2 years ago

Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.

community Do we have an agreed upon consensus on the best microneedling length?

DepartureRadiant4042 in Microneedling 9 upvotes 9 months ago

A video suggests 0.6mm microneedling is more effective for hair regrowth than 1.2mm, as it causes less trauma to stem cells. People commonly believe 1.5mm is best, but this may vary based on individual factors.

community Recent Study finds Laser caps are more effective than 5% minoxidil for AGA

TheBattleGnome in Research/Science 124 upvotes 11 months ago

Laser caps are found to be more effective than 5% minoxidil for treating hair loss, and when combined with minoxidil, they are even more effective. Some users report positive results with laser treatments, while others see no change; the devices are FDA approved, but opinions on their efficacy vary.

community New and Interesting HairLoss Studies/Papers/Reviews

TerpsandCaicos in Treatment 41 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Extreme hair and beard growth from Stemoxydine. Big 3 + 1?

VonHilsenburgEverc in Product 23 upvotes 4 years ago

Using a combination of Stemoxydine, minoxidil, dutasteride, and keto shampoo to achieve extreme hair and beard growth. The user has experienced positive results with terminal hairs at the hairline and an increase in density to their stubble after several weeks of use.

community Seven month progress. .5mg dut, 1.25mg minoxidil, % topical minoxidil, B3, Biotin, zinc , iron and microneedling

Full_Investigator215 in Is this regrowth? 153 upvotes 2 months ago

The user experienced significant hair regrowth over seven months using a combination of oral dutasteride, minoxidil, microneedling, vitamin D, biotin, zinc, and iron. They plan to continue treatments to prepare for a potential hair transplant.

community This serum outperformed Minoxidil in a recent study. Please debunk

Electronic-English 23 upvotes 5 years ago

A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

noeyys in Technology 107 upvotes 4 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community HairClone developing cell replacement treatments for Hair Loss

HairClone 6 upvotes 6 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community COMPLETE OVERVIEW of the Treatment of androgenetic alopecia in men

Honor_Bound 26 upvotes 10 years ago

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 823 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community The Real Cause Of Androgenetic Alopecia

AccutaneEffectsInfo in Research/Science 673 upvotes 3 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Fats on your Head to Stop Hair Loss?

thatdocman in Research/Science 140 upvotes 11 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community This is the best time in human history to be fighting hair loss

ToughEast838 in Treatment 194 upvotes 2 years ago

This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

Robbsaber in Research/Science 14 upvotes 8 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community Keratin microspheres - breakthrough

KieronR101 in Research/Science 13 upvotes 11 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

RadiantBlissUK in Research/Science 129 upvotes 1 year ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community It’s crazy how it’s 2018 and the only hair loss treatments we have feature undesirable side effects and/or aren’t even effective for many people.

HairAware20 136 upvotes 6 years ago

Hair loss treatments, including minoxidil, dermarolling, finasteride, dutasteride, hair transplants, hair systems, and shaving the head. The conversation covers various opinions on these treatments and mentions possible side effects as well as alternatives like wigs, vitamins, and lifestyle changes. The post expresses disappointment that there has been no major breakthrough in the field of hair loss treatments despite decades of research.

community Hair Transplant Progress / 3500 Grafts, 9 months on fin and oral minoxidil, should I switch to dut?

caffeine_energy in Satire 1879 upvotes 9 months ago

The conversation is about someone's hair transplant progress after 9 months on finasteride and oral minoxidil, considering switching to dutasteride. Specific treatments mentioned include hair transplant, finasteride, oral minoxidil, and a potential switch to dutasteride.

community This guy claims stem cells fixed his balding

AdKey759 in Is this regrowth? 301 upvotes 1 year ago

A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

community “You can’t regrow hair that’s gone.” HMB

Specialist_Ad4217 in Progress Pictures 32 upvotes 1 year ago

User regrew lost hair using microneedling, minoxidil, finasteride, Nizoral, fish oil, and collagen peptide. Progress was slow but constant, and patience was important.

community Perfect dermaroller routine

mintop751 in Advice 6 upvotes 5 years ago

The conversation is about using a 1mm derma roller for hair loss treatment, including cleaning the scalp with isopropyl alcohol and using castor oil mixed with coconut or olive oil afterward. The user seeks advice on the routine and mentions expected gains.

community 6 Month Progress (Sept 2021-Mar 2022) Fin,Min,Microneedling,Biotin, Ketoconazole Shampoo

Resident-Birthday-95 in Progress Pictures 644 upvotes 2 years ago

User shared 6-month progress using Fin, Min, Microneedling, Biotin, and Ketoconazole Shampoo for hair loss. They microneedle once a week, use 1.25 mg Fin daily, and apply topical Min twice a day.

community My RU58841 Progress / Hair loss journey

stefkamp in Progress Pictures 72 upvotes 3 years ago

A user shared their experience with hair loss treatments, including RU58841, ketoconazole shampoo, caffeine shampoo, and topical finasteride. They found RU58841 effective for diffuse thinning but experienced severe hair loss after stopping it; topical finasteride worked well for a receding hairline but caused side effects. They also use a charcoal shampoo and practice scalp massages.

community 6-months on Hims topical minoxidal and finasteride combination, and microneedling once every week or two. The before pic was taken with the front iphone camera so is lower resolution which makes a comparison hard, but perhaps seeing some minor gains in individual hairs thickening.

32082 in Progress Pictures 2 years ago

Using a combination of topical minoxidil and finasteride, plus microneedling, to treat hair loss; the progress made by the original poster over 6 months; the potential for further results with longer use; and the possibility of seeking alternatives such as a hair transplant or system.