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GlossarySkin Structure (Skin Anatomy)

complex organization of skin's layers and components

Skin structure, also known as skin anatomy or dermal structure, refers to the complex organization of the skin, which is the body's largest organ. It consists of three primary layers: the epidermis (the outermost layer providing a barrier and creating skin tone), the dermis (beneath the epidermis, containing tough connective tissue, hair follicles, and sweat glands), and the hypodermis (deeper subcutaneous tissue made of fat and connective tissue). These layers work together to protect the body, regulate temperature, and provide sensory information.

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Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens

in Research 413 upvotes 2 weeks ago

Treating androgenic alopecia with minoxidil, finasteride, and antiandrogens, alongside exercise, cryotherapy, and natural substances to stimulate cold receptors for better hair growth. The method focuses on enhancing treatment effectiveness by considering environmental and behavioral factors and the role of cold receptors and muscle stress.

community Keratin microspheres - breakthrough

in Research/Science 13 upvotes 9 months ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community Neck tension, and hair loss, I am 100 percent sure that there is a connection

in Treatment 19 upvotes 7 months ago

The user believes neck tension and poor posture contribute to hair loss, noticing improvements with yoga and muscle relaxation. Replies suggest androgenic alopecia as the cause and recommend exercises.

community Before/After 1 day topical minoxidil. Anyone else notice it gives you wrinkles and bags under your eyes?

in Satire 579 upvotes 1 year ago

This conversation discussed the side effects of Minoxidil for hair loss, with users sharing their experiences. Treatments such as Retinol and Tretinoin were suggested alongside topical or oral Minoxidil to reduce any negative impacts.

community Sensitive to Oral fin + RU. Am I screwed?

in Product 6 upvotes 3 years ago

Akinfenrawr experienced negative side effects from oral finasteride and RU58841, and is seeking alternative hair loss treatments. They discuss various options, including raloxifene, oral dutasteride, liposomal finasteride, Breezula, Pyrilutamide, SM04554, and sulforaphane, but have concerns about efficacy, availability, and cost.

community 1 year fin 1mg and minox. can see some density reclaimed

in Update 562 upvotes 3 years ago

User shared 1-year progress using finasteride 1mg and minoxidil, regaining hair density. Others praised the improvement and asked about side effects and additional treatments.

community How I started reversing Male Pattern Baldness naturally ?

in Question 6 upvotes 7 years ago

The user reversed male pattern baldness using a pro-thyroid diet, lifestyle changes, and scalp stimulation exercises, without Minoxidil or Finasteride. They reported reduced dandruff, itchiness, oiliness, and experienced hair regrowth and thickening over 15 months.

community After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?

in Finasteride/Dutasteride 95 upvotes 7 months ago

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.

community Physio-metabolic method of treating androgenic alopecia. Cold receptors. The relationship between DHT, cold receptors, minoxidil and antiandrogens.

in Research/Science 1 upvotes 2 weeks ago

A method for treating androgenic alopecia using minoxidil, antiandrogens, exercise, and cold exposure to promote hair growth. Environmental factors and lifestyle changes, like diet and exercise, can improve treatment effectiveness.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 4 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community Why do barbers never mention if you’re balding?

in Chat 317 upvotes 8 months ago

People are discussing why barbers often don't mention their clients' hair loss, with some sharing personal experiences where barbers did suggest treatments like finasteride (Fin) or mentioned the possibility of hair transplants. Some barbers avoid the topic to not offend clients, while others openly discuss it and recommend treatments or acknowledge the issue when asked.

community Rosemary oil's potency as a dht blocker

in Research/Science 65 upvotes 1 year ago

Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 122 upvotes 1 year ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Finasteride doesn't work for me in 2 years and my bloodtest result just came in.

in Progress Pictures 88 upvotes 1 year ago

A user has been treating hair loss with finasteride for two years without success and is experiencing an itchy scalp with seborrhea. Despite low DHT levels, they are still losing hair, suggesting that DHT might not be the main cause of their hair loss, and they are considering other treatments or causes.

community "Minoxidil and Caffeine: Reason behind hyper responders and non-responders."

in Research/Science 31 upvotes 1 year ago

Minoxidil and caffeine may interact, affecting hair growth results. Users shared mixed experiences, with some noticing improvements without caffeine and others still seeing results despite coffee consumption.

community A Different Take on Curing MBP

16 upvotes 5 years ago

Addressing hair loss by focusing on posture, blood flow, and craniofacial development. Methods include improving posture, cardiovascular activity, scalp massages, healthy diet, meditation, using minoxidil, and addressing craniofacial issues.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 6 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

community Is it possible for androgenic alopecia to begin at early adolescent years?

in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community Dr. Rassman’s topical liposomal finasteride - gyno question

in Finasteride/Dutasteride 13 upvotes 3 years ago

User discusses topical liposomal finasteride for hair loss, hoping to avoid breast growth side effect. Conversation includes using minoxidil, fluridil, and dermarolling, and mentions minimal systemic absorption of liposomal finasteride.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 4 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Diffuse thinning is the worst man

in Chat 248 upvotes 11 months ago

The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

community 3 Months Finasteride 1mg/day, Rogaine 2x day, Microneedling at 1,5mm, Biotin+Multivitamins

in Finasteride/Dutasteride 298 upvotes 3 years ago

User balding1337 shared their hair loss treatment success using Finasteride 1mg/day, Minoxidil 5% 2x/day, microneedling at 1.5mm, and Biotin+Multivitamins. Another user mentioned that microneedling with minoxidil is 3-4x more effective than minoxidil alone.

community Skin, Hair, and Nails by Pharmekal withdrawn from the market

in Product 1 upvotes 1 year ago

Skin, Hair, and Nails by Pharmekal was withdrawn from the market. Users discuss alternative supplements and treatments like Minoxidil, finasteride, and RU58841.

community My skin is always dry and flakes like chalk (25)

in Transgender 6 upvotes 8 months ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community Personal Anecdote: Be careful with oral min, it can have a bad impact on your skin

in Minoxidil 4 upvotes 10 months ago

Oral minoxidil can cause skin issues like redness and bumps. The user saw no hair improvement with oral minoxidil but noticed increased facial hair.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 65 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Anybody else notice improved skin/collagen on Dutasteride

in Finasteride/Dutasteride 6 upvotes 1 year ago

User switched from finasteride to combination dutasteride and finasteride for hair density improvement. They noticed less hair shedding and more youthful skin, with a reply suggesting less DHT could increase elastin in skin.

community Oral minoxidil can causes age skin?

in Minoxidil 8 upvotes 2 years ago

Oral minoxidil may cause skin aging, such as dark circles. To counteract aging, use tretinoin at night and broad-spectrum sunscreen during the day.

community Minoxidil and skin aging worry – which prevention methods (platelet rich plasma, microneedlig, mesotherapy, stem cells, co2, ultherapy, …)

in Chat 4 upvotes 2 years ago

User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.

community Topical application of Apple Skin 15% Procyanidin B2 extract makes hair noticeably thicker

in Treatment 7 upvotes 2 years ago

Hair loss discussion includes homemade 15% Procyanidin B2 apple skin extract as alternative to Minoxidil. User reports thicker hair, but no new growth yet.