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GlossarySignal Transducer and Activator of Transcription 1

protein involved in transmitting signals to activate specific genes

Signal Transducer and Activator of Transcription 1 (STAT1) is a protein that plays a crucial role in cellular responses to various stimuli, such as cytokines and growth factors. It helps transmit signals from the cell surface to the nucleus, where it activates specific genes involved in immune responses, cell growth, and apoptosis.

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community Physician here AMA – 30M oral Fin 1-1.25 mg daily

in Update 47 upvotes 2 years ago

Hair loss treatments, specifically the use of finasteride, microneedling and potentially oral minoxidil. People discussed their experiences with finasteride, its effects on sexual behaviors, as well as potential solutions such as tadalafil or using other growth factor signal peptides for hope in curing male pattern baldness.

community medication for hair loss spironolactone

in Female 3 upvotes 1 year ago

41-year-old female experienced slow hair thinning, took finasteride for a year, then switched to spironolactone. Irregular periods occurred, seeking advice on long-term side effects and considering a third medication.

community 25-31 recovery makes my hair almost unmanageable.

in Progress Pictures 17 upvotes 3 months ago

A user shared their hair recovery progress from ages 25-31, attributing success to quitting smoking, minoxidil, microneedling, and hormone therapy. They also mentioned being transgender and using hormone therapy.

community hmi115 is coming. Prepare yourselves for what's coming

in Technology 107 upvotes 11 months ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community Why is dht bad for scalp hair but good for hair on the rest of body?

in Satire 109 upvotes 1 year ago

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

community Month 5 – Fin, min, microneedling 1x month.

in Progress Pictures 70 upvotes 1 year ago

User made progress with hair loss using Fin, Min, and microneedling. Experienced side effects like improved skin, brain fog, and memory issues, but adjusting Fin dosage helped.

community New drug for hair loss announced by Amplifica

in Research/Science 161 upvotes 1 year ago

Amplifica starting clinical trials for new hair loss drug. SCUBE3 protein discovered, stimulates hair growth, could be alternative to Minoxidil and Finasteride.

community 2~ year progress update! 1mg FIN 2.5mg oral MIN daily. (26)

in Progress Pictures 1497 upvotes 2 weeks ago

User shared a 2-year progress update on hair regrowth using 1mg finasteride and 2.5mg oral minoxidil daily. They switched from topical to oral minoxidil for ease of use and showed significant improvement.

community Do finasteride/dutasteride actually inhibit only 40/50% scalp DHT

in Finasteride/Dutasteride 12 upvotes 1 month ago

Finasteride works by reducing DHT, which helps stop hair miniaturization. The user is on finasteride and believes it works due to its effect on growth factors and DHT reduction.

community 7 months fin, 10 months min, 4 months dut. Should I continue?

in Is this regrowth? 160 upvotes 2 months ago

The user has been using finasteride for 7 months, minoxidil for 10 months, and dutasteride for 4 months with minimal results and is considering stopping treatment. Replies suggest continuing treatment, adding microneedling, and checking DHT levels.

community M20 1.5 months vs 8 months fin + min

in Is this regrowth? 6 upvotes 3 months ago

A 20-year-old male has been using 1mg finasteride and 5% minoxidil daily for 1.5 to 8 months and is unsure about regrowth. Suggestions include continuing the treatment, trying microneedling, or considering oral minoxidil.

community Androgenic alopecia exclusively on the vertex of the scalp

in Chat 6 upvotes 3 months ago

A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.

community Not sure if fin is enough, still losing lots of hair

in Finasteride/Dutasteride 7 upvotes 3 months ago

The user has been on finasteride for 17 months to treat hair loss, with some improvement in the crown but still experiencing significant shedding. They are considering if finasteride alone is sufficient and are hesitant to use minoxidil due to a pre-existing condition, while another person suggests trying dutasteride.

community Can a folate deficiency make androgenetic alopecia worse?

in Treatment 1 upvotes 6 months ago

The user is treating androgenetic alopecia with finasteride and discovered a folic acid deficiency. They are asking if curing the deficiency can worsen or improve their hair condition.

community Has anyone tried PRP and Exosomes?

in Chat 2 upvotes 1 year ago

The user asked for opinions on a hair loss treatment involving PRP and Exosomes. They recently tried this treatment.

community RU users hands up I wanna hear your miracolous and horror stories.

in Treatment 44 upvotes 1 year ago

The experiences of users who have used RU58841 to treat hair loss, including both positive and negative effects. Some side effects reported include chest pain, joint pain in the hands, tinnitus, and increased heartbeat.

community Are there a lot of young folks here on fin?

in Chat 1 year ago

Young people who have used finasteride and minoxidil to treat hair loss, with generally positive results reported by those taking the treatments.

community Starting Year 2 of Low-Dose Oral Minoxidil – How Do I Look?

in Satire 1 year ago

This conversation is about a user's experience with low-dose oral Minoxidil for hair loss, and includes advice from other users who suggest trying finasteride or microneedling, as well as shaving off the remaining hair and seeking a hair transplant in Turkey. It was originally intended as satire but had to be clarified due to confusion.

community [19M] Before and after pics 8 months after consistent use of Finasteride 1 mg and Minoxidil 5% 1ml every night, ketokonazole2%+salicylic acid mild shampoo everyday. I’ve used minoxidil only for the frontal, most significant area of the scalp for regrowth as 1 ml is not enough for entire scalp

in Progress Pictures 220 upvotes 2 years ago

User shared before and after photos of 8 months using Finasteride 1mg and Minoxidil 5% 1ml nightly, with positive results and no side effects. Others praised the progress and suggested alternative treatments like topical fin, CB-03-01, or RU58841.

community 1 year fin 1mg and minox. can see some density reclaimed

in Update 562 upvotes 2 years ago

User shared 1-year progress using finasteride 1mg and minoxidil, regaining hair density. Others praised the improvement and asked about side effects and additional treatments.

community Anyone use Verteporfin with their hair transplant yet?

in Transplants 11 upvotes 2 years ago

User discusses using Verteporfin for hair regrowth after hair transplant. Replies mention successful follicle regrowth in studies and mice, questioning if it can be replicated in humans.

community Two month progress – Min/Dermarolling/Hair Savior Oil. Don’t mind the min-druff

in Progress Pictures 208 upvotes 3 years ago

User reports two-month progress using Min, dermarolling, and Hair Savior Oil. Others suggest adding Ketoconazole for dandruff and hair growth, and continuing Min use to maintain results.

community New potential hair loss treatment (news release)

in Treatment 186 upvotes 3 years ago

New potential hair loss treatment uses molecules from hairy moles to stimulate follicle growth. Topical solution requires less frequent application, like Botox injections a few times per year.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 117 upvotes 4 weeks ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 66 upvotes 4 weeks ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

community 10 months on fin and hairline destroyed.

in Finasteride/Dutasteride 45 upvotes 4 weeks ago

A user experienced severe hair shedding and hairline recession after 10 months on finasteride. They are considering switching to dutasteride or adding minoxidil.

community Caffiene shampoos left in for 2 minutes show comparable results to Minoxidil, and may work differently than Minoxidil, which can add to your stack, or work for non responders

in Research/Science 42 upvotes 2 months ago

Caffeine shampoos show comparable results to Minoxidil and may enhance its effects when used together. Caffeine can be detected in the scalp up to 24 hours after a 2-minute application, making it an affordable treatment option.

community I married my high school crush because of balding

in Satire 1052 upvotes 4 months ago

A man shared how his baldness led to reconnecting with his high school crush, resulting in marriage. The conversation includes jokes and varied opinions on balding, with no specific treatments mentioned.

community People here just don't know what they are letting themselves in for!

in Chat 123 upvotes 5 months ago

The conversation discusses hair loss treatments, emphasizing the importance of patience and sticking with a treatment for at least 12-18 months before judging its effectiveness or adding new treatments. Users share experiences and agree that introducing treatments too quickly can lead to panic and negative outcomes.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 5 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.