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GlossaryTriglycerides

molecules storing energy as fat in your blood

Triglycerides, also known as triacylglycerols (TAGs), are a type of fat found in your blood. They are composed of three fatty acid molecules attached to a glycerol backbone. When you eat, your body converts any calories it doesn't need to use right away into triglycerides, which are stored in fat cells. High levels of triglycerides can increase the risk of heart disease and are often associated with conditions like obesity and metabolic syndrome.

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community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 1 year ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community PSA: Get your Vitamin D levels checked!

in Treatment 113 upvotes 1 year ago

A user improved their hair health by taking 50,000 IU of vitamin D3 weekly due to a deficiency. Others discussed the potential link between vitamin D and hair growth, with some sharing similar experiences and emphasizing the importance of monitoring vitamin D levels and consulting with doctors.

community sebum overproduction on fin 1mg and hair thinning

in Finasteride/Dutasteride 3 upvotes 6 months ago

User is experiencing hair thinning and sebum overproduction after starting finasteride and a hair growth supplement containing biotin, iron, zinc, and calcium. They suspect the finasteride might be fake but have noticed a side effect of watery semen.

community For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction?

in Finasteride/Dutasteride 6 upvotes 1 year ago

The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.

community Does Koshine reduce sebum and Itchiness? I would like to hear experiences

in Treatment 6 upvotes 3 months ago

Users discuss whether Koshine reduces sebum and scalp itchiness. Some report reduced sebum and seborrheic dermatitis, while others debate the effectiveness of anti-androgens like RU58841 for hair loss.

community biotin leads to acne and sebum on scalp ??

in Finasteride/Dutasteride 1 upvotes 6 months ago

User is experiencing increased sebum, dandruff, and acne after taking a supplement containing biotin, iron, zinc, and calcium pantothenate along with finasteride. They are questioning if biotin is the cause and whether they should stop taking it.

community Can the ingredients in a sebum-regulating shampoo induce hair diameter reduction?

in Product 2 upvotes 1 month ago

A user experienced hair thinning and scalp issues after using a sebum-regulating shampoo and perm treatments. They are advised to consider potential allergies, try a simple shampoo, and research treatments like finasteride for possible male pattern baldness.

community Can absorption be intervened by oil, sebum etc?

in Treatment 3 upvotes 2 months ago

The conversation discusses whether oily scalp and sebum can hinder the absorption of topical hair loss treatments like Minoxidil and Finasteride, even when using tretinoin. The user is skeptical about the effectiveness of these treatments due to their oily scalp condition.

community Topical androgens for alopecia to treat sebum overproduction on the face

in Product 1 upvotes 8 months ago

The conversation discusses using scalp antiandrogens like RU58841, pyrilutamide, or fluridil on the face to reduce sebum production, noting that clascoterone (winlevi) is an approved facial antiandrogen with underwhelming reviews.

community Serum DHT CAN'T cause hair loss. Sebum DHT is a better measurement.

in Research/Science 19 upvotes 2 months ago

Serum DHT is mostly inactive; sebum DHT is a better measure for hair loss. Users discuss using finasteride, dutasteride, and topical treatments like KX826 and RU58841 for better scalp DHT suppression.

community Explanation for "dutasteride destroyed my hair"

in Finasteride/Dutasteride 4 upvotes 5 months ago

Dutasteride can drastically reduce sebum production, leading to dryer hair and shedding. Alternating shampoos and periodic silica supplementation can improve hair quality and thickness.

community Update on "nothing working": think I found my issue

in Update 21 upvotes 5 months ago

The user discovered that a buildup of sebum and residue was preventing Minoxidil and finasteride from working effectively. After thorough scalp cleaning, hair shedding reduced significantly, and microneedling became more effective.

community 16, female, losing a ton of hair

in Female 6 upvotes 6 months ago

A 16-year-old female experiencing severe hair loss and sebum buildup, likely due to telogen effluvium and PCOS, is currently using vitamin D3 supplements, Redenser serum, and T follihair supplements. Recommendations include addressing PCOS first and consulting a doctor.

community Washing hair every day instead of a couple times a week

in Treatment 7 upvotes 3 years ago

The user discusses the potential impact of external DHT in sebum on hair loss and plans to wash their hair daily with salicylic acid exfoliation. They believe this might help reduce hair loss despite internal factors.

community My experience with Pyrilutamide

in Update 3 upvotes 8 months ago

The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

in Treatment 4 upvotes 9 months ago

Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

community Winlevi for 1 month on scalp. Testing it out so y’all don’t have to.

in Treatment 52 upvotes 1 year ago

A user is testing clascoterone (Winlevi) on their scalp for hair loss and has noticed a reduction in scalp sebum after one month. They are also using other unspecified treatments and plan to provide an update after the second month.

community Any 'recipes' for home made natural shampoos ?

in Treatment 1 upvotes 1 year ago

A user is seeking homemade, organic shampoo recipes to reduce scalp greasiness and excessive sebum without using commercial shampoos. They dislike the texture and smell of amla paste.

community RU58841 to stop excessive oil production?

in Research/Science 7 upvotes 5 months ago

The user discusses using Minoxidil for hair loss and is considering RU58841 to reduce excessive oil production. They seek advice on RU58841's effectiveness in blocking sebum production.

community is my multi vitamin a high dose ?

in Finasteride/Dutasteride 6 upvotes 5 months ago

User experienced hair loss after weight loss and started using finasteride 1mg and a multivitamin called HAIRGRO. They noticed increased oily skin and sebum production and are unsure if they should continue the multivitamin.

community I have not seen a single person who claims dutasteride destroyed their hair post a picture of the before/after

in Finasteride/Dutasteride 123 upvotes 6 months ago

The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community Vitamin C and hair growth PH levels

in Product 34 upvotes 2 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community Ru58841 stops seb derm ( the itching)?

in Treatment 8 upvotes 1 year ago

RU58841 is discussed as a treatment that stops scalp itching when used with finasteride or dutasteride. The user is considering trying RU58841 due to persistent itching despite using the "big 3" treatments.

community What all oils could be useful to augment hair growth

in Finasteride/Dutasteride 4 upvotes 5 months ago

The user uses 1mg fin every other day, a topical solution of 5% min + 0.1% fin nightly, and seeks advice on oils for hair growth. Replies suggest oils are ineffective and recommend sticking with fin and min treatments.

community Opinion on possible regrowth (incl. early fin/min results)

in Is this regrowth? 6 upvotes 6 months ago

The user experienced significant hair loss due to health issues and is now using finasteride and minoxidil for nearly 3 months. They are hopeful about tiny hairs/dots indicating regrowth and are considering a hair transplant later in the year.

community Loosing hope after not seeing improvement in hair regrowth.

in Minoxidil 7 upvotes 11 months ago

A 22-year-old male is not seeing hair regrowth after using minoxidil and finasteride for a year and additional treatments for three months. Suggestions include improving scalp absorption with sea salt and trying a lipid-based solution, microneedling, and possibly switching to dutasteride if no improvement after 1-2 years.

community How I paused my hair loss by curing seborrheic dermatitis

in Treatment 107 upvotes 1 year ago

User Wonderful_Tonight910 suffered from hair loss and seborrheic dermatitis for years. After using irritant-free shampoo, their scalp improved, hair loss stopped, and new hair growth appeared.

community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

in Progress Pictures 83 upvotes 2 years ago

Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.