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Glossary scaffolds

structures supporting cell growth and tissue formation

In the context of hair and biology, scaffolds refer to structures made from biocompatible materials that provide a supportive framework for cells to grow and form new tissues. These scaffolds can be used in regenerative medicine to help repair or replace damaged tissues, including hair follicles, by mimicking the natural extracellular matrix and promoting cell adhesion, proliferation, and differentiation.

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community Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway

53 upvotes 8 years ago

A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.

community If we can clone a sheep why we can't cure baldness till now

in Research/Science 181 upvotes 11 months ago

Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.

community Sugars ARE important for hair growth | Glycosaminoglycans as Hair Growth Stimulant

74 upvotes 2 years ago

Glycosaminoglycans are important for hair growth, and combining minoxidil with tretinoin and Biopeptide-CL may enhance hair growth by boosting glycosaminoglycan levels and improving the hair follicle environment. Users discussed the potential effectiveness and future of these treatments.

community If you’re on the fence about Finasteride, don’t wait!

in Finasteride/Dutasteride 78 upvotes 3 years ago

Finasteride, a medication for hair loss that has both positive and negative effects. Users discussed their own personal experiences with the drug as well as potential side-effects of taking it, such as erectile dysfunction or gynecomastia. Suggestions were also made about starting at a lower dosage to minimize these risks.

community Finasteride and “anti-aging” effects

in Treatment 218 upvotes 1 year ago

Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

community Summary of Procapil video by Haircafe

2 upvotes 1 year ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

76 upvotes 2 years ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community scrap fin/dut, it's time for handstands

177 upvotes 8 months ago

The conversation humorously suggests that doing daily handstands can regrow hair by improving blood flow to the scalp, dismissing traditional treatments like finasteride and minoxidil. It satirically claims that gravity is the real cause of hair loss, with users joking about the effects of gravity on hair growth.

community clascoterone powder to topical diy

4 upvotes 4 months ago

The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

community 4 days after a hair transplant

1501 upvotes 1 year ago

A satirical discussion about a hair transplant, with humorous comments on graft placement and clinic choice. The conversation includes references to a "Rebuild a Scalp Clinic" and jokes about using pubic hair and overharvesting.

community Reasonable and safe stack? Bloodwork within.

1 upvotes 2 years ago

A 26-year-old male is using a combination of clomiphene, minoxidil, tadalafil, bupropion, and lisdexamfetamine to address low testosterone, ED, depression, and focus issues. He seeks input on the safety and efficacy of this regimen, which also includes magnesium, zinc, and fish oil supplements.

community Sandalore experiment

18 upvotes 7 years ago

A user added sandalore to minoxidil for hair loss, observing some vellus hair growth and less scalp inflammation. Others tried sandalore with mixed results, discussing dosage and effectiveness compared to minoxidil and finasteride.

community 11 months oral miraclegro, 9 months topical roundup, 10 months spectracide, 6 months Cow Dung mesotherapy + weekly Foot stepping session

4 upvotes 11 months ago

The conversation humorously discusses hair loss treatments, mentioning "oral miraclegro," "topical roundup," "spectracide," "Cow Dung mesotherapy," and "weekly Foot stepping sessions." The user jokingly considers switching to "weed and feed" as a treatment.

community Saw a flyer for a bald meetup this weekend

69 upvotes 1 month ago

A user humorously mentions a flyer for a bald meetup. Another user jokes about attending once they accept their hair loss.

community Clascoterone - what we have right now

24 upvotes 6 months ago

Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

community I made the ultimate shedding table

in Satire 122 upvotes 1 year ago

The conversation humorously discusses hair loss and treatments, specifically finasteride and topical minoxidil, with the OP joking about making art from shed hair. Users engage in light-hearted banter about hair loss and related habits.

community New & Improved Hair Growth Stack for Maximum Results

5 upvotes 1 year ago

A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

community Clascoterone Scalp 2 Results in July?

4 upvotes 2 months ago

The conversation discusses the anticipation of clascoterone scalp treatment results for hair loss, with concerns about its availability and high cost. Users express hope for positive outcomes and affordable access.

community Sule Hair Clinic is having a coordinated marketing scam via Tressless

68 upvotes 3 months ago

Sule Hair Clinic is suspected of using fake reviews on Reddit to promote their hair transplant services. Users are warned to be cautious and report these posts as potential ads.

community Looks like This sub is a gold mine

866 upvotes 7 months ago

Bald men in Mozambique are being targeted due to superstitions that their heads contain gold, leading to dangerous rituals. The conversation humorously discusses this belief and its implications.

community Calecim (PTT-6) Advanced Hair System with Topical Exosomes and Growth Factors for Hair Growth

1 year ago

Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hair growth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.

community Stacking on top of Min/ Fin - adding hair supplements?

in Product 1 upvotes 1 year ago

The conversation is about adding Swisse Hair Nutrition for Men, which contains saw palmetto and various vitamins, to a Minoxidil and finasteride regimen to potentially enhance hair growth. The user is seeking feedback on the effectiveness of stacking these supplements with their current treatment.

community Is keratin fusion bond good alternative to clip on hair patch for diffused thinners

4 upvotes 3 years ago

Keratin fusion bonds are discussed as an alternative to clip-on hair patches for men with diffused thinning. The conversation explores different styling options for hair loss.

community Pyrludimide (KX-826) or Breezula (clascoterone)

9 upvotes 5 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community Clascoterone 5% solution infographic

130 upvotes 9 months ago

Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

community 4 month update - nuclear stack, 42m

in Progress Pictures 256 upvotes 2 years ago

A 42-year-old user shared a 4-month update on their hair regrowth using a "nuclear stack" including oral and topical minoxidil, dutasteride, RU58841, micro-needling, keto shampoo, saw palmetto, biotin, multivitamins, scalp massages, and inversion table. They reported significant progress with minimal side effects and plan to continue the routine.

community What are we thinking about this SCUBE3 boys

in Product 7 upvotes 11 months ago

SCUBE3 is a promising new molecule that can restart hair growth by reawakening dormant hair follicles. Users express skepticism about its availability timeline, with some hoping for release by 2026.

community What dermaroller or dermastamp do you like?

in Treatment 5 upvotes 2 years ago

The conversation is about recommending safe and effective dermaroller or dermastamp brands for hair loss treatment. Users discuss avoiding cheap options to prevent scalp damage and share usage frequency.

community Amplifica: Hope or Cope? A Review of Their Pipeline

9 upvotes 1 month ago

Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

community Amplifica and AMP-303 clinical phase 1

9 upvotes 2 years ago

Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.