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    Did you mean Endoplasmic Reticulum?
    GlossaryEndoplasmic Reticulum

    network of membranes in cells for protein and lipid synthesis

    The Endoplasmic Reticulum (ER) is a network of membranes within a cell that plays a crucial role in the synthesis, folding, modification, and transport of proteins and lipids. There are two types: Rough ER, which is studded with ribosomes and primarily involved in protein synthesis, and Smooth ER, which lacks ribosomes and is involved in lipid synthesis and detoxification processes.

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      community Had a rough week. What to do now?

      in Treatment  36 upvotes 3 months ago
      The user had a rough week after being told they couldn't get a hair transplant due to insufficient donor area and worsening balding. They were advised to increase their oral Minoxidil dosage and consider switching from Finasteride to Dutasteride.

      community Finally decided to post / Started June 26th

      in Progress Pictures  11 upvotes 10 months ago
      The user started hair loss treatment on June 26th using 1.25mg finasteride, 1ml 5% minoxidil twice a day, derma rolling every 1.5 weeks, and 2% ketoconazole foam twice a week. They experienced significant hair growth in the first four months, with thicker hair and improved hairline, but had a rough shedding phase in November.

      community My experience with Alfatradiol so far

      in Treatment  10 upvotes 1 year ago
      User is 16, experiencing hair loss, and using minoxidil and alfatradiol. Shedding decreased, new hairs growing on temples, but unsure if alfatradiol is effective or if future shedding will occur.

      community Making the jump to hair systems

      in Hair Systems  27 upvotes 3 years ago
      19-year-old with Lichen Planopilaris tried various treatments unsuccessfully. Now considering hair systems, seeking experiences and opinions.

      community Getting hit hard by the shed….

      in Progress Pictures  85 upvotes 5 months ago
      A user is experiencing significant hair shedding after starting a treatment regimen of 1mg oral finasteride, 3mg oral minoxidil, 2.5mg biotin, and vitamins. Despite the shedding, they remain optimistic and plan to continue the treatment for a year before making any conclusions.

      community 3 Months of 2.5 minoxidil + 1mg finasteride

      in Progress Pictures  38 upvotes 1 month ago
      User reports hair improvement after 3 months using 2.5% minoxidil, 1mg finasteride, weekly Nizoral, bi-weekly microneedling, and nightly rosemary oil. Shedding has decreased, and no significant side effects were noted.

      community This guy claims stem cells fixed his balding

      in Is this regrowth?  301 upvotes 1 year ago
      A man who claimed to have regrown his hair using stem cell treatment, sparking a debate about its effectiveness and cost. Some users suggested he might be using other treatments or substances, while others shared their own experiences with stem cell therapy for hair loss.

      community Woke up with the urge to cut all of it off

      in Shaved/buzzed  31 upvotes 2 months ago
      A user decided to buzz their thinning hair after starting Dutasteride, feeling liberated by the change. Other users shared similar experiences, with some using treatments like Finasteride and Minoxidil to manage hair loss.

      community How long does the RU58841 shed last?

      in Treatment  2 upvotes 6 months ago
      The conversation discusses the duration of hair shedding caused by RU58841. The user is stressed and seeking information on how long the shedding phase lasts.

      community Progress but at different times?

      in Is this regrowth?  6 upvotes 7 months ago
      The user has been taking 1.25mg of oral minoxidil and 1mg of finasteride for a year and added topical minoxidil in January. They noticed hair improvement but are experiencing uneven regrowth, with the hairline improving and the middle part worsening.

      community Survived First Monte. Shedding is real

      in Progress Pictures  370 upvotes 7 months ago
      The user is treating hair loss with 1mg finasteride every other day, daily topical minoxidil, and weekly derma rolling, and is considering using hair fibers for special occasions. There is a discussion about the initial shedding phase of minoxidil treatment and the importance of consistent photo conditions to track progress.

      community Did quitting caffeine turn me into a minoxidil responder?

      in Minoxidil  2 upvotes 9 months ago
      A user shared that after quitting caffeine and restarting oral minoxidil, they experienced significant hair regrowth, suggesting that caffeine might interfere with minoxidil's effectiveness by blocking adenosine receptors. They also mentioned side effects like water retention and dizziness, which subsided after a few weeks, and are not using any DHT blockers.

      community Year and a half progress pictures

      in Progress Pictures  13 upvotes 1 year ago
      The post discusses a user's hair loss treatment routine, which includes daily 1mg finasteride, twice daily topical rogaine, biotin vitamin intake, and a new microneedling regimen of 0.5mm three times a week. The user is turning 24 next month.

      community 1.5 years fin results ( 0.25mg ED)

      in Progress Pictures  165 upvotes 2 months ago
      A user shared their 1.5-year experience using 0.25mg finasteride daily for hair loss, noting significant hair quality improvements and reduced scalp itch but mild erectile dysfunction. They managed side effects with daily 2.5mg Cialis and 5mg citrulline and plan to continue this routine.

      community Ordered copper peptides - how to apply?

      in Treatment  1 upvotes 3 months ago
      Gizzela is unsure about the dosage and frequency of copper peptides and asks if they can be used with Stemoxydine. They seek advice on applying these treatments together.

      community Stop expecting results in 2 months!

      in Treatment  125 upvotes 6 months ago
      People discussing hair loss treatments emphasize the need for patience, as results from using finasteride and minoxidil can take 8-12 months or longer. Some users report early signs of improvement, while others experience continued shedding or slower progress.

      community 11 month progress on a cocktail regiment

      in Progress Pictures  441 upvotes 1 year ago
      The user "Dismal_Library_2264" shared their 11-month progress on a hair loss treatment regimen. They used dutasteride, topical minoxidil, dermarolling, a hair serum, and specific shampoos. They experienced some side effects but were overall satisfied with the results.

      community How insane is this oral min shed?

      in Progress Pictures  111 upvotes 1 year ago
      A user started taking 0.625mg oral minoxidil daily for hair loss, increased the dose to 1.25mg, and experienced a significant shed, losing 70% of scalp density. They cannot tolerate finasteride due to side effects but are hopeful for hair regrowth despite the shedding.
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