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      community What happened with verteporfin?

       30 upvotes 1 month ago
      Verteporfin, combined with microneedling, shows promise for hair regrowth by allowing hair follicles to grow in wounds, but it's expensive and painful. Pai-1 inhibitors may also help prevent hair loss by degrading fibrosis, and some users continue using minoxidil alongside these treatments.

      community Thinking about using PP405 and RU58841

       1 upvotes 8 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.

      community Pyrilutamide bulk powder purchasing

      in Product  2 upvotes 1 year ago
      Pyrilutamide is being used effectively for hair loss with no side effects, and the user is seeking a cheaper bulk supplier. Users discuss the difficulty of finding affordable, trustworthy sources, with some suggesting potential suppliers.

      community How to minimize RU going systemic?

       5 upvotes 4 years ago
      An 18-year-old is considering using RU58841 for aggressive hair loss and is also thinking about taking creatine. Users suggest avoiding creatine due to its potential to increase DHT and recommend using topical finasteride instead.

      community Diy dutesteride please help MCT oil or PG?

       1 upvotes 9 months ago
      A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

      community Thoughts on this? Supposed everychem pp405 results after 2 weeks

       17 upvotes 5 months ago
      PP405 is being discussed as a promising hair loss treatment, potentially effective when combined with minoxidil and pyrilutamide. Some users are skeptical about rapid hair regrowth claims, while others are considering alternatives like GT20029 and pyrilutamide instead of finasteride.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 4 months ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

       59 upvotes 5 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community For everyone buying 2-deoxy-d-ribose (2ddr)

       12 upvotes 1 year ago
      The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

      community Thoughts on Lactobacillus Reuteri 6475?

       4 upvotes 1 year ago
      Lactobacillus reuteri 6475 is being used by a person who reports healthier hair after one month, despite initial shedding. The discussion includes speculation about its effects on gut bacteria and scalp inflammation.

      community Looking for the new RU58841 source in EU

      2 years ago
      The user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and ask for advice on shipping within the EU and product quality, while also mentioning their current hair loss treatment involves mixing RU with Stemoxydine and Alfatradiol.

      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

       6 upvotes 9 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community PP405 Phase 2a press release with early results

       700 upvotes 1 year ago
      PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

      community Mfs claiming pig lard solves hair loss now?😭

      in Satire  8 upvotes 11 months ago
      People are humorously discussing unconventional hair loss remedies like pig lard and raw liver, while also mentioning treatments like Minoxidil, finasteride, and RU58841. They mock the idea that seed oils cause balding and criticize misinformation.

      community Castor oil home brews and regimens?

       4 upvotes 8 years ago
      Using castor oil, coconut oil, rosemary, tea tree oil, peppermint oil, and other essential oils for hair loss prevention. Emu oil and derma rollers are also discussed, with caution advised for coconut oil's comedogenic properties and taking castor oil orally.

      community PP405 2a study was a safety study. Some rational explaining.

       22 upvotes 1 year ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 7 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community TCA 35% chemical peel, don't try this shit at home.

       11 upvotes 7 months ago
      The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

      community Is adding RCP(redensyl, capixyl, procapil) over min+fin make sense?

       5 upvotes 1 year ago
      The conversation discusses the effectiveness of adding RCP (redensyl, capixyl, procapil) to a hair loss treatment regimen that includes minoxidil and finasteride. Users share experiences, suggesting RCP may not be as effective as minoxidil, but could be useful for creating topical solutions.

      community Does This Invalidate PP405 Completely?

      6 months ago
      PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.

      community JXL082 is not PP405 and Everychem followed the wrong lead

       41 upvotes 1 year ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.