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GlossaryReproductive Toxicity

harmful effects on reproductive system from certain substances

Reproductive toxicity refers to the harmful effects that certain substances can have on the reproductive system, potentially leading to issues such as infertility, developmental problems in offspring, or adverse effects on sexual function. These toxic effects can impact both males and females and may result from exposure to chemicals, drugs, or environmental agents.

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community Spironolactone for 11 years, finasteride for almost 5 years, started oral minoxidil in November 😢 ended oral contraceptive in Dec.

in Progress Pictures 224 upvotes 7 months ago

A user shared their 11-year experience with spironolactone and nearly 5 years with finasteride for hair loss, recently adding oral minoxidil and stopping birth control. Various treatments were discussed, including organic options, checking for underlying health issues, considering dutasteride, and the potential role of progesterone in hair loss.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Dutasteride causing us to have… girl babies?

in Finasteride/Dutasteride 26 upvotes 1 year ago

User Kylo313 used dutasteride for 20 years and had two daughters, questioning if dutasteride affects the likelihood of having male vs female children. Replies mostly request hairline photos and discuss anecdotal experiences, with some suggesting correlation doesn't imply causation and that gender determination isn't affected by dutasteride.

community Why we need to be more open as men

in Chat 1 year ago

The emotional difficulty of hair loss for men and how society can be more understanding; various methods to address hair loss, such as finasteride, minoxidil, and RU58841; and why it is important to normalize caring about one's looks.

community I felt it when he said it is devastating to lose your hair as a man. Spoken like someone who has felt the horror of male parent blandness.

in Satire 400 upvotes 1 year ago

The devastating effects of male pattern baldness and how it can be seen as a societal double standard, with many people mocking those who experience hair loss. People shared their own experiences of hair loss and discussed potential treatments such as hair transplants, Minoxidil, finasteride, and RU58841.

community Tiny hair coming in after switching from fin to dut

in Finasteride/Dutasteride 88 upvotes 4 weeks ago

After switching from finasteride to dutasteride, the user noticed new hair growth and experienced manageable shedding. They reported feeling great on dutasteride with minimal side effects, using Cialis occasionally for libido issues.

community Hair loss 30F - thoughts on red light therapy vs min/fin?

in Female 6 upvotes 1 month ago

The conversation discusses hair loss treatments for a 30-year-old female, comparing red light therapy with minoxidil and finasteride. Concerns about hormonal impact and potential pregnancy are raised, with suggestions to consider spironolactone and microneedling, while emphasizing the importance of consulting a dermatologist.

community Topical fin and min and swallowing semen

in Finasteride/Dutasteride 118 upvotes 5 months ago

A user asked if it's safe to swallow semen from a partner using topical finasteride and minoxidil. Responses varied, but most suggested it's likely safe, with minimal risk from small amounts of finasteride in semen.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 5 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community started RU58841 today and am panicing

in Treatment 8 upvotes 1 year ago

A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

community 4 months on fin/min/dermaroll/niz

in Is this regrowth? 234 upvotes 1 year ago

A 35-year-old who has been using topical and oral Minoxidil and Finasteride with dermarolling and Nizoral for four months, experiencing improved hair health but not yet full coverage on the crown. Others have responded encouragingly to this progress.

community Anything you use without scientific backing, just trusting your gut?

in Research/Science 13 upvotes 1 year ago

The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.

community So excited! Just got dutasteride for free when I forever thought I’d have to pay! 😭

in Finasteride/Dutasteride 30 upvotes 2 years ago

A user who was able to get dutasteride for free with their insurance, and another user mentioning that finasteride is only covered if it is used for medical reasons.

community 2 years after using finasteride

in Update 1208 upvotes 2 years ago

A user's two-year journey of using finasteride and minoxidil to treat hair loss, with other users providing advice, tips, and encouragement.

community Complete Guide to Orally Taking Topical Minoxidil

in DANGEROUS / UNPROVEN 149 upvotes 2 years ago

Taking topical minoxidil orally for hair loss treatment, discussing safety, dosing, side effects, and FAQs. Users express concerns about safety and potential heart damage, while others share experiences and results.

community Starting With "Strut" Topical: Dut %0.1 + Min %7.5 + Tretinoin %0.0125 + Biotin (and more)

in Treatment 9 upvotes 3 years ago

The user started a hair loss treatment with a topical solution containing 0.1% Dutasteride, 7.5% Minoxidil, 0.0125% Tretinoin, and Biotin, along with a multivitamin, Ashwagandha, CBD oil, Retinol, and Caffeine Solution. They experienced some shedding and scalp irritation, leading to a reduction in the use of the caffeine solution.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 674 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community A little over two years on Dut

in Finasteride/Dutasteride 59 upvotes 1 month ago

A 23-year-old male has been using Dutasteride for over two years to address hair thinning, with some success in temple regrowth but continued thinning on top. He is considering adding Minoxidil to his routine and is contemplating lifestyle changes like quitting smoking and drinking to improve hair density.

community Balding at the age of 17 years old

in Chat 8 upvotes 2 months ago

A 17-year-old experiencing hair loss is using Minoxidil but is hesitant about Finasteride due to potential side effects. Others recommend Finasteride for its effectiveness and suggest alternatives like vitamins and derma rollers.

community Increased adipose tissue (being overweight) in males may increase likelyhood of finasterde side effects

in Research/Science 29 upvotes 2 months ago

Being overweight may increase finasteride side effects due to higher aromatase activity converting testosterone to estradiol. Maintaining a healthy weight could reduce these side effects.

community Dutasteride takes 1-3 months to work in the scalp. Not weeks. Be careful.

in Finasteride/Dutasteride 41 upvotes 3 months ago

Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.

community I think we all hop on estrogen. It's the only angle

in Satire 83 upvotes 3 months ago

The conversation humorously discusses hair loss treatments, including Minoxidil, finasteride, RU58841, and topical 17 alpha estradiol, with some users joking about transitioning to female to avoid baldness. The overall tone is satirical, emphasizing self-acceptance and the lengths people might consider for hair restoration.

community Results after more than 1.5 years on Finasteride

in Finasteride/Dutasteride 243 upvotes 3 months ago

A user shared their experience with finasteride for hair loss, noting it slowed but didn't stop their hair loss, and they quit after 1.5 years. Suggestions included trying dutasteride, adding minoxidil, and maintaining a healthy lifestyle.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 4 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community This subreddit is 250K members strong, and only 95 likes for this game-changing Verteporfin research? It's pitiful. We need to be encouraging and supportive to any hair transplant surgeon willing to do research on Verteporfin! Go like the video, leave an encouraging comment, and spread this video

in Research/Science 108 upvotes 4 months ago

The conversation discusses the need for more support and awareness for Verteporfin research in hair loss treatment, emphasizing its potential benefits and quick implementation due to existing FDA approval. Users express skepticism due to past scams but acknowledge the importance of encouraging doctors to conduct trials.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 6 months ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?

in Finasteride/Dutasteride 95 upvotes 6 months ago

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.

community How to know if shedding is from tren or minoxidil?

in Minoxidil 5 upvotes 7 months ago

The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

community Theory And Observation: Why Being Bald Can Really Work

in Shaved/buzzed 88 upvotes 8 months ago

The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

community 23M (yes 23, I'm not kidding), ~6 month progress. I'm on the Big 4 + Vitamin Supplement.

in Progress Pictures 447 upvotes 9 months ago

A 23-year-old male shared his 6-month hair loss progress using Minoxidil, Finasteride, Ketoconazole shampoo, microneedling, and vitamin supplements. He noticed hair loss at 19, which accelerated during the pandemic.