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GlossaryProstate Health Index

blood test combining three markers to detect prostate cancer

The Prostate Health Index (PHI) is a blood test that helps to improve the accuracy of prostate cancer detection. It combines three different prostate-specific markers—total PSA, free PSA, and [-2]proPSA—into a single score, which can help differentiate between benign prostate conditions and prostate cancer, thereby reducing unnecessary biopsies.

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 100 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community ‘ Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm’ Thoughts? Concerns?

in Finasteride/Dutasteride 65 upvotes 3 years ago

The potential health risks associated with long-term use of finasteride and dutasteride, with some responses pointing out the low quality of the journal that published the review article as well as highlighting other alternatives such as keto or minoxidil, and RU58841.

community We all regret not acting on hair loss sooner. What is something else we can prevent if we act now?

in Chat 94 upvotes 8 months ago

The conversation discusses the importance of early action in various aspects of life such as healthy eating, skincare, fitness, sleep, financial planning, and career development to prevent future health issues, regret, and financial hardship. Specific treatments mentioned include using sunscreen and tretinoin for anti-aging skincare.

community I've been afraid to start Finasteride treatment for 5 years, on it for 2 weeks, regret that hadn't started it earlier and here's my story

in Finasteride/Dutasteride 31 upvotes 2 years ago

A 28-year-old male, losing hair since his teens, started taking 0.31 mg finasteride daily for two weeks with no side effects and regrets not starting earlier. He tried various treatments like minoxidil, scalp massages, and vitamins but found finasteride most effective.

community Dr Kyle Gillett on topical Dutasteride

in Finasteride/Dutasteride 56 upvotes 1 year ago

The potential effectiveness of topical dutasteride, as well as other hair loss treatments such as finasteride, RU58841, minoxidil, and various vitamins. Experiences from users who have used these treatments were shared.

community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 1 year ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community U.S Court let Merck hide secrets about Finasteride.

in Finasteride/Dutasteride 301 upvotes 1 year ago

Hair loss discussion involving finasteride's side effects and effectiveness. Users shared mixed experiences, with some reporting side effects and others seeing positive results.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community After 1.5 years+ on dut/fin hairless has finally slowed!

in Finasteride/Dutasteride 77 upvotes 3 years ago

After 1.5 years on finasteride and dutasteride with continued hair loss, the user noticed a significant reduction in hair shedding, attributing it to the consistent use of finasteride, along with a no-shampoo approach, multivitamins, vitamin D, and restarting minoxidil. Other users shared their happiness for the improvement and noted that hair loss can fluctuate naturally over time.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 70 upvotes 3 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community I Get Side-Effects from Anti-Androgens

in Finasteride/Dutasteride 6 upvotes 3 years ago

Someone looking for solutions to their hair loss, who has tried and failed to tolerate anti-androgen treatments such as finasteride, CB-03-01, RU58841, and Eucapil. The user is seeking advice and understanding of their extreme sensitivity to these treatments.

community If you’re sitting there wondering, “I’m losing my hair, what do I do?” then read my advice here. I’ve been fighting the fight for 7 years, with great success. (pictures included)

in Question 109 upvotes 11 years ago

Fighting hair loss with "The Big 3" treatments of Propecia, Rogaine and Nizoral shampoo, as well as specific advice on how to use these products. People have shared their long-term success stories and some have discussed the side effects of finasteride. Other suggestions included Lipogaine and Pura D'or Hair Loss Prevention Therapy Shampoo & Conditioner.

community Finasteride 1.25mg 10 month Progress

in Progress Pictures 148 upvotes 6 months ago

The user shared a 10-month hair loss treatment routine using Finasteride, ketoconazole shampoo, and Red Light Therapy, noting significant progress and considering adding Dutasteride. They experienced initial side effects and changes in libido, but overall reduced hair shedding and regrowth, especially at the temples.

community Hey guys I’m in desperate need for opinions from long term finasteride users

in Finasteride/Dutasteride 28 upvotes 1 year ago

Whether taking finasteride and dutasteride can cause penile shrinkage, with long-term users providing their personal experiences.

community 1 year on fin. No results. I give up.

in Finasteride/Dutasteride 1 year ago

A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 2 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

community The theory that explains everything – First Evidence of Hair regrow attributed to upregulating 3aHSD

in Treatment 175 upvotes 3 years ago

Hair regrowth treatment involving 3aHSD enzyme shows 6% improvement in 18 weeks. Sulforaphane, L-Menthol, and Dexpanthenol are potential ingredients for new hair loss solution.

community How to know if shedding is from tren or minoxidil?

in Minoxidil 6 upvotes 4 months ago

The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

community Mid 40s Fin only - 12 month update.

in Progress Pictures 508 upvotes 7 months ago

A user in their mid-40s shared a 12-month update on using finasteride for hair loss, showing significant improvement. They started seeing thicker hair and regrowth after 3 months, with no side effects noticed.

community The truth about Dutasteride (w/ sources)

in Finasteride/Dutasteride 51 upvotes 1 year ago

The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.

community 1MG Fin 14 Months Results

in Finasteride/Dutasteride 160 upvotes 3 years ago

A user's 14-month journey with finasteride, microneedling, and Nizoral to treat hair loss. They experienced some side effects such as ball ache, needing to pee constantly, and less semen, but the results were generally positive.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 1 month ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community Is Eucapil (fluridil) actually legit?

in Treatment 8 upvotes 2 years ago

User asks about Eucapil (fluridil) for hair loss, its effectiveness, safety, and where to buy in Australia. Others share experiences and purchase options.

community Been on Propecia since 1997, recently switched to Topical Finasteride.. follow for updates, or to ask any questions about 23 years on Propecia.

in Finasteride/Dutasteride 103 upvotes 3 years ago

User spent 23 years on Finasteride with side effects like weight gain and reduced libido. Switched to topical Finasteride, side effects reduced and waiting for results.

community 4.5 months on Finasteride 1mg a day, topical Minoxidil 5% twice a day, and ketoconazole shampoo 1% every time I shower.

in Progress Pictures 178 upvotes 6 months ago

The user is using finasteride, minoxidil, and ketoconazole shampoo for hair loss and stopped derma stamping to prepare for a future hair transplant. They are considering adding tretinoin to their treatment.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 109 upvotes 5 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community My dad 61y/o healed from full bald to full head of hair

in Finasteride/Dutasteride 175 upvotes 7 months ago

A user's 61-year-old father regained a full head of hair after four years on dutasteride for his prostate and five months of weight loss and exercise. The user decided to switch from finasteride to dutasteride and continue exercising, inspired by his father's results.

community Dermatologist told me to quit fin after turning 40

in Finasteride/Dutasteride 193 upvotes 10 months ago

A dermatologist advised a patient to stop taking finasteride (fin) after turning 40 due to potential risk of aggressive prostate cancer. The patient and others in the conversation debated this advice, discussing the relationship between finasteride, prostate cancer, and hair loss, and considering alternatives like topical finasteride.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 117 upvotes 4 weeks ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community 8 months on 5mg fin daily, 5% min twice daily, and hrt(mtf). Thought my hair was unrecoverable before but now I’m so happy.

in Transgender 1899 upvotes 1 year ago

A user named "LordGeek101" shared their positive experience with hair regrowth after using 5mg of finasteride daily, 5% minoxidil twice daily, and hormone replacement therapy (HRT) for 8 months. The user is transgender (MTF) and mentioned that the larger dose of finasteride was recommended by their doctor for better chances of hair revival.