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      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  449 upvotes 2 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Verteporfin trials in hair transplant patients begin

      in Transplants  40 upvotes 2 years ago
      A clinical trial for Verteporfin as a hair loss treatment, and the potential for greater progress in treatments for hair loss in the future. Common treatments such as Minoxidil, Finasteride and RU58841 were discussed.

      community HAIR REGENERATION HUMAN TRIALS with Verteporfin

      in Research/Science  13 upvotes 2 years ago
      A new human trial using an FDA-approved treatment for wound healing called Verteporfin, which may potentially be able to reverse scarring and regrow hair in that area. The trial is only lasting one month so far.

      community Around how much should hair cloning cost?

      in Technology  5 upvotes 2 years ago
      Hair cloning is expected to be significantly more expensive than hair transplants, potentially reaching six figures. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community microneedling, do the gains go away?

      in Microneedling  23 upvotes 2 years ago
      Microneedling promotes hair growth by increasing circulation and collagen production, with gains potentially lasting longer than those from minoxidil. Some users report sustained results after stopping microneedling, unlike with minoxidil and finasteride.

      community Earliest we can get legitimate pyrilutamide

      in Research/Science  46 upvotes 2 years ago
      Pyrilutamide, a drug in phase 3 trials in China, potentially becoming available in late 2023 or early 2024; Finasteride being used as a current treatment for hair loss; and the possibility of joining a group buy for black market versions of Pyrilutamide.

      community The Importance of Not Rushing Your Treatment Protocol

      in Treatment  10 upvotes 2 years ago
      Taking a slow and steady approach to treating hair loss, as well as the potential risks of combining too many treatments. The post suggests trialling individual treatments (such as Minoxidil, finasteride, or RU58841) for an extended period before adding more into your treatment protocol.

      community Fuck hair loss; acquire beard.

      in Shaved/buzzed  931 upvotes 2 years ago
      A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 2 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Why is human evolution like this 😂

      in Chat 2 years ago
      Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

      community HairClone: Good info from their site

      in Technology  10 upvotes 2 years ago
      HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

      community Dutasteride Mesotherapy, has anyone tried this?

      in Treatment  6 upvotes 3 years ago
      The conversation is about trying dutasteride mesotherapy for hair loss, with concerns about its effectiveness and potential side effects compared to finasteride. The user is considering this treatment available in California.

      community Retinol or tretnoin with minoxidil?

      in Minoxidil  6 upvotes 3 years ago
      Combining retinol or tretinoin with minoxidil for hair loss treatment. Users discuss the potential benefits and effectiveness of this combination.

      community RU58841 carrier - PG/Ethanol vs KB solution?

      in Treatment  2 upvotes 3 years ago
      The conversation discusses the differences between PG/Ethanol and KB solutions for RU58841 application, focusing on potential scalp irritation. KB solution is suggested for those allergic to PG, though both contain ethanol which can dry the scalp.

      community Vitamin D advice I received after seeing my blood work.

      in Research/Science  90 upvotes 3 years ago
      The conversation discusses the importance of taking vitamin D with food for better absorption and its potential role in hair loss. Some users also suggest taking vitamin D with K2, getting sunlight, and using finasteride for hair loss treatment.

      community Is latanoprost/bimatoprost actually that effective?

      in Product  7 upvotes 3 years ago
      Latanoprost/bimatoprost's effectiveness in hair loss treatment is discussed, with its potential to convert vellus hairs to terminal hairs. It works differently from minoxidil and finasteride, and may be best for hairline application, but is not a replacement for them due to price and mechanism.

      community The theory that explains everything. Please help me make this big!

      in Research/Science  2448 upvotes 3 years ago
      The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

      community When you pop your first Fin pill

      in Satire 3 years ago
      Hair loss treatment using Fin, Minoxidil and RU58841 with discussion about potential side effects and the power of nocebo effect.

      community HNY, any word on Breezula for 2021?

      in Product  6 upvotes 3 years ago
      Breezula passed a clinical trial in August and there are questions about its availability in 2021 and potential delays due to Covid. No specific treatments were discussed.

      community The Big Fat Layer II

      in Research/Science  26 upvotes 3 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community Why haven’t we seen anything about this

      in Research/Science  18 upvotes 4 years ago
      A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

      community Hair Cloning, Trials were supposed to begin 2020-2021

      in Technology  48 upvotes 4 years ago
      The conversation discusses hair cloning trials expected to start in 2020-2021 and mentions concerns about potential delays due to the Coronavirus. Treatments like Minoxidil, finasteride, and RU58841 are referenced.