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      community PP405 Updates Feel Like Breadcrumbs at This Point

       11 upvotes 3 months ago
      PP405 updates are seen as vague and lacking substance, causing frustration among users. Some users report positive effects from using minoxidil and dutasteride, while others remain skeptical about new treatments.

      community How likely do you think it is for PP405 to come out?

      in Research/Science  21 upvotes 11 months ago
      PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

      community Has anyone used Dutanol or Dutaheal (Indian generic) or other dutasteride tablets?

      7 months ago
      People are discussing switching to Indian generic dutasteride tablets like Dutanol and Dutaheal due to cost concerns, with some users reporting positive results when taken with a high-fat meal. Users have shared experiences with different brands, noting varying effectiveness and side effects compared to finasteride.

      community Let’s get PP405 trending on Twitter!

      in Chat  69 upvotes 1 year ago
      People are excited about a new hair loss treatment, PP405, and some suggest using Twitter to increase its visibility. Current treatments mentioned include finasteride, minoxidil, and dutasteride, but skepticism remains about the effectiveness of new treatments.

      community Topical latanoprost chance of eye color change?

      in Product  1 upvotes 1 year ago
      The user is using oral minoxidil for hair growth and is considering adding topical latanoprost, but is concerned about potential eye color change. They are seeking advice on the effectiveness of latanoprost for hair thickening and the risk of eye color change.

      community Anyone using oral castor oil in their stack?

       4 upvotes 2 years ago
      The conversation discusses using oral castor oil as a hair growth stimulant for beard and scalp hair. One user questions its use, noting castor oil is typically a laxative in the Philippines.

      community Alcohol Free Minoxidil? Azaleic Acid added?

       4 upvotes 9 years ago
      The user is experiencing a burning sensation from using minoxidil and is considering trying an alcohol-free version with added azelaic acid. They are also using finasteride and seeking reliable, low-cost alternatives for minoxidil.

      community Breezula is a good alternative

       8 upvotes 5 months ago
      Clascoterone 5% solution (Breezula) is a promising alternative for androgenetic alopecia, showing continued hair growth with consistent use and no significant side effects. It may be suitable for those who cannot tolerate finasteride or dutasteride, especially when trying to conceive.

      community Juicero is not an analogy for PP405. Stop bringing that up.

       8 upvotes 8 months ago
      PP405 is a medicine, and Google Ventures is funding its development based on evidence from each phase, unlike their investment in Juicero, which was a trend-based gamble. Investing in medicine is a calculated risk, not reliant on being "cool."

      community Breezula/Winlevi

       5 upvotes 6 years ago
      Breezula/Winlevi's potential use for hair loss is discussed, with concerns about its effectiveness compared to Breezula's higher concentration. Users express interest in a topical treatment with minimal side effects, noting that Breezula's efficacy may decline after six months.

      community Petition: Make PP405 available tomorrow instead of 2030

       331 upvotes 1 year ago
      PP405, a promising hair loss treatment, is expected to be available by 2027, with faster trials due to its topical nature. Users are eager for its release, comparing it to existing treatments like minoxidil and finasteride, but remain cautious about its long-term effectiveness.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 8 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community Important thing i discovered that makes ru58841 very effective

       87 upvotes 7 months ago
      RU58841 is more effective when mixed with isopropyl alcohol instead of minoxidil, as water in minoxidil degrades RU58841. Applying RU58841 separately from minoxidil, with an hour gap, enhances hair growth results.

      community Hair transplants and PP405 - Irregular density concern

       18 upvotes 5 months ago
      The conversation discusses concerns about getting a hair transplant with the potential release of a new treatment, PP405, which may regrow dormant hair follicles. The user is currently using Minoxidil, Derma, and Keto but is waiting to start finasteride or dutasteride.

      community How do you keep your bloodsugar low on finasteride?

       12 upvotes 2 years ago
      Finasteride may affect blood sugar and metabolism, with some users reporting increased blood sugar and changes in body composition. To manage potential side effects, users suggest exercise, intermittent fasting, and dietary adjustments.

      community VDPHL01 works really quickly .. apparently?

       50 upvotes 5 months ago
      VDPHL01 shows faster and stronger hair growth compared to standard minoxidil, with no major side effects reported. Users discuss combining it with other treatments like dutasteride and finasteride for better results, while expressing skepticism about the effectiveness of PP405.

      community The future of hair loss drugs.

       34 upvotes 7 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.

      community Will PP405 need to be used indefinitely, like minoxidil?

       31 upvotes 11 months ago
      PP405 may not need daily use like minoxidil, but finasteride might still be needed to maintain hair regrowth. PP405 reawakens dormant hair follicles, potentially offering a long-term solution, though not a permanent cure.

      community Caffeine & ketoconozole results past couple months

       5 upvotes 3 years ago
      The user has been using Alpecin and Nizoral, which improved hair texture and reduced shedding and itching. They are hesitant to use finasteride or minoxidil and are seeking other suggestions to slow hair loss and improve hair appearance.

      community New article on PP405..........

      in Research/Science  109 upvotes 1 year ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community Ru + glycerin making scalp greasy . help !!

       2 upvotes 1 year ago
      The user is experiencing a greasy and dandruff-prone scalp from using RU58841 with glycerin and is seeking alternative carriers for seborrheic dermatitis. They are also using dutasteride 0.5mg.

      community Welp - pp405 conference showed nothing

       81 upvotes 5 months ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 10 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Topical bimatoprost or latanoprost

      in Product  11 upvotes 1 year ago
      OP is considering adding topical bimatoprost or latanoprost to their hair loss treatment, which already includes oral minoxidil, and is seeking reliable sources for these products. Users discuss the effectiveness and sourcing of these treatments, with some using bimatoprost for both hairline and eyelashes, and others planning to use latanoprost mixed with finasteride.

      community Retinol substitute for Tretinoin

       4 upvotes 2 years ago
      The user is seeking a substitute for Tretinoin to enhance the effectiveness of Minoxidil for hair loss. They are considering using Retinol as an alternative.

      community What are the alternatives to spironolactone for AGA?

       7 upvotes 1 year ago
      The user experienced side effects from spironolactone and is seeking alternatives for androgenetic alopecia (AGA), considering saw palmetto but unsure of its effectiveness. They are also exploring the possibility of using topical spironolactone, despite availability challenges.