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      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      5 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community Can we all agree that PP405 is now 4 years away

       94 upvotes 1 year ago
      PP405 is expected to be available in 2028, with ongoing discussions about its timeline and potential effectiveness. Current treatments mentioned include sublingual Minoxidil and Vederamicd, with some users experiencing side effects from oral Minoxidil.

      community Theoretically, could PP405 help grow a beard?

       6 upvotes 1 year ago
      PP405 is discussed as a potential treatment for growing a beard in patchy areas, with some users suggesting minoxidil as an alternative. Experiences with minoxidil vary, with some users reporting significant beard growth and others seeing minimal results.

      community Mix Pyrilutamide powder in Minoxidil solution?

       3 upvotes 2 years ago
      Mixing Pyrilutamide powder with Minoxidil solution is being considered. The Minoxidil solution contains Minoxidil 5%, Azelaic acid 5%, ABN complex 0.8%, Retinol 0.025%, Caffeine 0.001%, and a delivery vehicle.

      community Diagnosed with MPB at 16 (Male)

       50 upvotes 2 years ago
      A 16-year-old diagnosed with male pattern baldness (MPB) was prescribed hair vitamins, vitamin D, a non-ketoconazole shampoo, and redenysl + serum, with a suggestion for GFC or IHRF treatments. Some users recommended minoxidil, ketoconazole, and derma stamping, while others advised against certain treatments until the age of 18.

      community PP405 Never Worked: the follicles were already activated at baseline

       17 upvotes 3 months ago
      PP405 was ineffective for hair growth as some follicles were already active before treatment, raising doubts about its efficacy. Users discussed other hair loss treatments like Minoxidil, finasteride, and RU58841, expressing skepticism and hope for future solutions.

      community M29 Dut/Min/Microneedle/Tretinoin

       24 upvotes 2 years ago
      A user has been using finasteride since 2018, switched to dutasteride, and added minoxidil, microneedling, and a tretinoin/spiro compound. They are pleased with the results and hopeful for more improvement.

      community minoxidil (15 months) and pyrilutamide (46 days) results.

       24 upvotes 2 years ago
      OP used minoxidil for 15 months and pyrilutamide for 46 days, achieving desired results without side effects. Users discussed alternatives like dutasteride and finasteride, with concerns about side effects like erectile dysfunction.

      community Anyone heard of or have experience using baricitinib?

       1 upvotes 3 years ago
      The conversation is about baricitinib, a medicine that can help with hair loss, and why it isn't more popular or widely discussed. No specific experiences with the treatment were shared.

      community Thoughts on the future of pp405?

       43 upvotes 10 months ago
      PP405 is considered a promising hair loss treatment, potentially replacing minoxidil but not finasteride. Users are hopeful for future treatments like GT20029 and VDPHL01, while remaining cautious about effectiveness and side effects.

      community Rejected for the 2nd time for the VDPHL01 Clinical Trials (believe it or not!)

      in Chat  12 upvotes 1 year ago
      The user was rejected from participating in a clinical trial for an extended-release oral Minoxidil due to having rheumatoid arthritis, despite initially being accepted. They had stopped using Dutasteride and Minoxidil to qualify but continued using other treatments like RU58841 and red light therapy.

      community 14 Month Topical Fin/Min .1%/10% + microneedling update

       31 upvotes 1 year ago
      The user reports progress in hair regrowth using topical finasteride/minoxidil, microneedling, topical dutasteride, latanoprost, and MSM supplements. They express frustration over the lack of interaction on progress posts compared to trivial topics.

      community Update on PP405 Trails - Pelage

       14 upvotes 7 months ago
      The conversation discusses interest in participating in PP405 trials for hair loss treatment, with users expressing uncertainty about eligibility due to location. Participants are eager for updates and willing to pay for shipping if trials are limited to America.

      community So is this the actual trial results for pp405?????

       94 upvotes 5 months ago
      PP405 shows promising results for hair growth, potentially outperforming finasteride without side effects like erectile dysfunction. Users discuss using treatments like minoxidil, pyrilutamide, nizoral, and alfatradiol while waiting for PP405's availability.

      community Almost 4 months, before and after of pyrilutamide .5% once daily

       23 upvotes 4 months ago
      The user experienced significant hair regrowth using a combination of minoxidil, alfatradiol, pyrilutamide, and nizoral, despite previous intolerance to finasteride. They emphasize the importance of consistency in treatment and are optimistic about the results, noting no side effects so far.

      community New article on PP405..........

      in Research/Science  109 upvotes 1 year ago
      Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

      community SCUBE 3 (the last hair bender)

       2 upvotes 1 year ago
      SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinical trials. No specific updates or new information are provided in the conversation.

      community M27 Fin/Min (topical) was fun while it lasted

       19 upvotes 2 years ago
      The user experienced high liver enzyme levels, possibly due to topical finasteride or supplements, and decided to stop using finasteride while continuing minoxidil. After stopping finasteride and supplements, liver levels returned to normal, suggesting finasteride or supplements might have been the cause.

      community Any Indians using Minichek F 5% ???

       2 upvotes 2 years ago
      A user asks about experiences with Minichek F 5% with Procapil, specifically its drying time. Responses discuss the effectiveness and drying time of the treatment.

      community Any updates on PP405 other than official 2a results?

       17 upvotes 11 months ago
      People are seeking updates on PP405, a hair loss treatment, with no new information available beyond old news and speculation about trial phases. A user shared concerns about hair shedding after using finasteride and minoxidil, with others suggesting it might be temporary shedding.

      community PTD-DBM from Infiniwell- have you tried it?

       6 upvotes 3 years ago
      The conversation is about using PTD-DBM Peptide from Infiniwell for hair loss. The original poster is seeking feedback on its effectiveness.

      community Consensus on pyrilutamide? i want to start but not sure…

       5 upvotes 2 years ago
      The post and conversation discuss the effectiveness of pyrilutamide for hair loss, with comparisons to finasteride and RU58841. Users express skepticism due to failed trials and high costs, with some waiting for more data before trying pyrilutamide.