Can we all agree that PP405 is now 4 years away
    Chat 8/20/2025

    At a glance
    In this general discussion post, the primary subjects mentioned are
    Minoxidil (sublingual)
    💊 Minoxidil (oral)
    the tone is 😐 neutral.

    Other terms

    PP405 is expected to be available in 2028, with ongoing discussions about its timeline and potential effectiveness. Current treatments mentioned include sublingual Minoxidil and Vederamicd, with some users experiencing side effects from oral Minoxidil.
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      community Prepare to be disappointed by PP405

      in Research/Science  24 upvotes 1 week ago
      Delayed release oral minoxidil is seen as a promising advancement for hair loss treatment, offering safer, higher doses and more consistent hair follicle stimulation compared to current options. However, it is not expected to replace finasteride or dutasteride, as it does not prevent androgenetic alopecia.

      community How far are we from a treatment better than finasteride?

      in Treatment  129 upvotes 11 months ago
      Dutasteride is more effective than finasteride for hair loss as it blocks more of the enzyme causing hair loss. New treatments like stem cell therapies and alternatives to minoxidil are being explored, but major advancements are still years away.

      community Does This Invalidate PP405 Completely?

      in Research/Science 3 days ago
      PP405's effectiveness in increasing hair density is questioned due to a small sample size, despite investment from Google Ventures. Users express skepticism and suggest waiting for more conclusive results.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 1 week ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

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