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    Glossary OVOL3

    gene regulating hair follicle development and growth cycles

    OVOL3 is a gene that encodes a transcription factor involved in the regulation of hair follicle development and differentiation. It plays a crucial role in the transition of hair follicles from the growth phase (anagen) to the regression phase (catagen), and its proper function is essential for maintaining healthy hair growth cycles.

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      community Amplifica and AMP-303 clinical phase 1

       9 upvotes 2 years ago
      Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

      community SCUBE 3 (the last hair bender)

       2 upvotes 1 year ago
      SCUBE3 and Amplifica's progress in hair loss treatment is being discussed, with inquiries about their current status and clinical trials. No specific updates or new information are provided in the conversation.

      community Recent progress on stack including third verteporfin procedure

       13 upvotes 1 month ago
      The user shared progress on hair regrowth after a third verteporfin procedure, using oral dutasteride, extended-release oral minoxidil, and occasional microneedling. The results were positively received by others.

      community 3 month progress, Fin, Min, 0.5mm dermaroller

       108 upvotes 2 years ago
      The conversation is about a user's 3-month hair regrowth progress using finasteride, minoxidil, and a 0.5mm dermaroller, with recent addition of caffeine shampoo. Users are responding positively and inquiring about application methods.

      community SUBE3 for sale in the gray market?

       5 upvotes 1 year ago
      SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

      community 3 month Progress update w/before and afters - 4 in 1 topical solution

       16 upvotes 1 year ago
      A user shared their 3-month progress using a topical solution containing 0.3% finasteride, 7% minoxidil, 2.2% ketoconazole, and 0.2% biotin, reporting improvements in thinning areas. Another user mentioned using oral finasteride, oral minoxidil, dutasteride, and minoxidil foam, discussing costs and side effects.

      community Fin year 3 results/maintainence

      in Progress Pictures  332 upvotes 1 year ago
      A user has used finasteride for three years to maintain hair thickness and is considering adding minoxidil for temple recession. They report no side effects and are satisfied, while others discuss minoxidil's pros and cons and share hair treatment experiences.

      community MinoxidilMax just launched a 0.3% tretinoin topical. Would you try?

       15 upvotes 5 years ago
      The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.

      community What are we thinking about this SCUBE3 boys

      in Product  7 upvotes 11 months ago
      SCUBE3 is a promising new molecule that can restart hair growth by reawakening dormant hair follicles. Users express skepticism about its availability timeline, with some hoping for release by 2026.

      community Trinov 3 Months Results

       5 upvotes 7 years ago
      The user has been using Minoxidil for 4 years and recently added a derma pen and Trinov to their regimen, but results are inconclusive after 3 months. Some users suggest Trinov is ineffective and recommend alternatives like Clascoterone (Breezula) for better results.

      community 3 month progress on min/fin....hopeful

       26 upvotes 1 week ago
      The conversation discusses a user's three-month progress using Minoxidil and finasteride for hair loss. Users suggest shaving for better comparison and mention adding topical dutasteride.

      community 3 year update - Dut, Min, Niz. 1.5mm roller

       641 upvotes 1 year ago
      The user shared a 3-year hair restoration update using 0.5mg dutasteride daily, 5% minoxidil foam twice daily, a 1.5mm derma roller twice a month, and Nizoral shampoo. They reported significant improvement and maintenance of hair, with minimal side effects, and are satisfied with the results at age 40.

      community I’m taking Veradermics VDPHL01 - AMA

      in Treatment  174 upvotes 4 months ago
      A participant using Veradermics VDPHL01, an extended-release oral minoxidil, experienced significant hair regrowth from Norwood 6 to Norwood 3V without side effects. They plan to use dutasteride after the treatment to maintain results.

      community Expectations control for SCUBE3

       20 upvotes 2 years ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community 3 month Update 1mg Fin and monoxidl

      in Progress Pictures  23 upvotes 2 months ago
      The user shared a 3-month update on using 1 mg finasteride daily, minoxidil foam twice daily, derma stamping weekly, and ketoconazole shampoo twice weekly for hair loss. They are considering adding tretinoin cream and mentioned a possible future hair transplant.

      community Pp405 trials question - 2a/2b,

       6 upvotes 10 months ago
      PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

      community VDPHL01 phase-2/3 results comparison

      in Research/Science  128 upvotes 4 months ago
      The conversation discusses hair loss treatments, focusing on a new slow-release oral minoxidil compared to topical minoxidil and finasteride. The results show that twice-daily dosing of the new treatment is slightly more effective than once-daily, but concerns about cost, side effects, and the accuracy of reported results remain.

      community when is kintor going to start phase 3 for gt20029?

       6 upvotes 2 years ago
      The conversation is about the timeline for Kintor's phase 3 trials for GT20029 and the potential release of the product in three years. It also mentions treatments like Minoxidil, finasteride, and RU58841.