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      community Has anyone tried Spartan Root Activator shampoo?

       1 upvotes 8 months ago
      The conversation discusses the effectiveness of Spartan Root Activator shampoo for hair loss. It mentions treatments like Minoxidil, finasteride, and RU58841.

      community A Short Recap on PP405 and AAD 2026

      in Update 5 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community This shedding phase is brutal man…

       590 upvotes 1 year ago
      The user is experiencing a difficult shedding phase after starting a hair loss treatment with oral finasteride, topical minoxidil, and microneedling. Despite the shedding, they remain hopeful for regrowth and plan to continue the treatment, encouraged by others' positive results.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

       13 upvotes 3 years ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community Lost ground on Dut, Min, RU, etc (5 yrs… 2021->2026)

       16 upvotes 5 months ago
      The user has been using a combination of treatments including Dutasteride, Minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy to address hair loss but continues to experience shedding and density loss. Despite high testosterone and iron levels, the user is frustrated with the lack of improvement and is considering adjusting treatment or exploring other options like a hair transplant.

      community Shedding whilst on Dut and topical min

       2 upvotes 6 months ago
      A 26-year-old from the UK is experiencing increased hair thinning despite using dutasteride and topical minoxidil. They are considering additional treatments like ketoconazole shampoo, oral minoxidil, and possibly RU58841, while seeking advice on managing side effects and exploring other options.

      community My Idea for a possible new hairloss treatment

       53 upvotes 6 years ago
      Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.

      community Topical min and dermarolling with seborrheic dermatitis

       4 upvotes 5 months ago
      The user is managing hair loss with oral finasteride, recently switching to dutasteride, and topical minoxidil, but faces challenges due to seborrheic dermatitis. They seek advice on effective regrowth methods that don't worsen their condition, with suggestions including various shampoos like Vichy Dercos and ketoconazole.

      community Can trichodynia ruin an exosome treatment?

      in Chat  1 upvotes 2 years ago
      The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

      community can someone help me identify these pls

      in Treatment 9 months ago
      The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

      community Making your own RT1640 in China

      4 years ago
      RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

      community Horrible news, Stemson Therapeutics has shut down

       193 upvotes 1 year ago
      Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

      community Dry and itchy scalp after ru58841 and keto. Advice needed

       3 upvotes 4 years ago
      The user experienced severe scalp itching after using RU58841 and ketoconazole shampoo, despite trying moisturizing treatments. They suspect the issue is related to the propylene glycol in the vehicle and are seeking alternatives.

      community Shedding tremendously on RU5841

      in Chat  6 upvotes 4 months ago
      The user is experiencing significant hair shedding after starting RU58841, despite using dutasteride and oral minoxidil for over a year without stabilization. Others suggest continuing the treatment as shedding can be a normal phase, but caution that RU58841 is unpredictable.

      community lost all my gains switching from liquid to foam

       4 upvotes 7 years ago
      Switching from liquid to foam minoxidil led to hair loss for OP, possibly due to a second shedding cycle. OP experienced allergic reactions to propylene glycol in the liquid form, causing dandruff and itchiness, which improved after switching to foam.

      community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell

       13 upvotes 11 years ago
      A new treatment using dermal sheath cup cells may regrow hair and could require repeat treatments every 8 years. Users discuss ongoing trials and plan to use finasteride and minoxidil until the treatment is available.

      community Possible natural pp405 solution

      in Research/Science  45 upvotes 1 year ago
      Rotenone, a natural plant extract, may promote hair growth by increasing LDH activity and blocking MPC in the scalp, but it carries risks due to its toxicity. The suggested formulation includes Barbasco extract, DMSO, propylene glycol or PEG-400, ethanol, and a carrier oil.

      community Diffuse thinning temporary solution

      in Product  12 upvotes 1 year ago
      A user with diffuse thinning recommends a root cover-up spray as a temporary, medication-free solution. They plan to consult a dermatologist for treatments like Minoxidil and finasteride while using the spray for special occasions.

      community Scared of Oral Minoxidil Dread Shed

       1 upvotes 1 week ago
      A woman with PCOS, AGA, and TE is worried about hair loss from oral minoxidil (OM) and is considering topical treatment to avoid shedding. A user reassures her that while shedding may occur, it won't lead to baldness, just temporary thinning.

      community Huge hair shedding on Astaxanthin.

       2 upvotes 5 months ago
      Astaxanthin may cause increased hair shedding, affecting even transplanted hair and eyebrows. The user has tried various treatments for androgenic alopecia, including minoxidil, finasteride, and RU58841.

      community Shedding phase... It's brutal lol

      in Progress Pictures  8 upvotes 4 months ago
      The user is using finasteride and topical minoxidil for hair loss after previously trying them separately without success. They are experiencing a shedding phase but are committed to the treatment.