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      community New 2025 study: high dose oral minoxidil (up to 10mg)

      in Research/Science  80 upvotes 11 months ago
      High-dose oral minoxidil (>5 mg/day) can increase hair density in some men with androgenetic alopecia, but side effects like extra body hair and heart issues are common. Gradual dose increase is advised, but adverse effects may lead to discontinuation or dose adjustments.

      community 2dDR experiment. Seems to be doing something.

       11 upvotes 1 month ago
      A user shared their experience using 2-deoxy-D-ribose (2dDR) for hair regrowth, noting early positive results without side effects, alongside their long-term use of minoxidil and finasteride. They mentioned 2dDR's potential effectiveness in boosting blood flow to hair follicles and its availability online.

      community Pp405 trials question - 2a/2b,

       6 upvotes 10 months ago
      PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

      community 7 Months of 0.4 mg Dutasteride and 2 mg Minoxidil

      in Update  104 upvotes 6 months ago
      OP used 0.4 mg Dutasteride and 2 mg Minoxidil for 7 months, seeing significant hair density improvement without a noticeable shedding phase. OP takes a combined oral pill from Musely and is in their early forties.

      community Hair density change in 7 months… unreal.

       354 upvotes 1 year ago
      The user experienced significant hair density improvement over seven months using finasteride, topical minoxidil, Nizoral shampoo, and supplements like biotin and vitamin D. They also used a derma stamp with rosemary and peppermint oil, noting no side effects from finasteride.

      community Nearly 3 months update dutesteride + minoxidil

      in Is this regrowth?  39 upvotes 4 months ago
      OP reports minimal shedding and improved hair thickness after nearly 3 months on a combination of dutasteride and minoxidil. Users discuss realistic expectations, hair density improvement, and the cost of branded versus generic medications.

      community Your progress pics are measuring lighting more than hair

      in Technology  11 upvotes 1 month ago
      A dermatologist is developing a device to standardize hair progress photos for those using finasteride and minoxidil, aiming to provide consistent data on hair status. Users express skepticism about its practicality and cost, suggesting it might be more suitable for clinics than consumers.

      community Duality of (diffuse thinning) man

      in Chat  67 upvotes 1 year ago
      The user has been using finasteride for over two years with mixed results and is considering starting dutasteride and oral minoxidil, though both are hard to obtain. They are also contemplating a hair transplant in the future due to diffuse thinning.

      community Hair transplants and PP405 - Irregular density concern

       18 upvotes 5 months ago
      The conversation discusses concerns about getting a hair transplant with the potential release of a new treatment, PP405, which may regrow dormant hair follicles. The user is currently using Minoxidil, Derma, and Keto but is waiting to start finasteride or dutasteride.

      community VDPHL01 phase-2/3 results comparison

      in Research/Science  128 upvotes 4 months ago
      The conversation discusses hair loss treatments, focusing on a new slow-release oral minoxidil compared to topical minoxidil and finasteride. The results show that twice-daily dosing of the new treatment is slightly more effective than once-daily, but concerns about cost, side effects, and the accuracy of reported results remain.

      community Rational Review of Pelage Results

      in Chat  11 upvotes 1 year ago
      A treatment showed a 20% hair density increase in weeks, with nearly a third of participants experiencing significant results, while questions remain about its long-term efficacy and effectiveness across different scalp areas. There is interest in combining it with finasteride and minoxidil for potentially better outcomes.

      community Method for creating 0.01% duta topical solution, will this work?

      in Microneedling  4 upvotes 10 months ago
      The conversation discusses creating a 0.01% topical dutasteride solution mixed with minoxidil for hair loss treatment, with concerns about absorption and effectiveness. Some users suggest that dutasteride needs specific formulation for better absorption, while others recommend oral use for practicality.

      community Heavy diffuse shedding 4+ months into dutasteride

       6 upvotes 3 weeks ago
      A user in their 20s with androgenetic alopecia is experiencing heavy hair shedding after starting dutasteride and oral minoxidil, with concerns about scalp sensitivity and low vitamin D. They plan to consult a dermatologist for further evaluation, while others in the conversation share similar experiences with shedding after starting dutasteride.

      community Locklabs + Dutasteride Formula

       1 upvotes 8 months ago
      The conversation discusses the effectiveness and value of a Locklabs pill containing finasteride, minoxidil, biotin, and a low dose of dutasteride for hair loss. The user is uncertain if the .1mg dutasteride dosage is sufficient and worth the cost.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 5 months ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community Well boys... I've joined the Master Race

      in Finasteride/Dutasteride  31 upvotes 6 months ago
      Finasteride has been effective for maintaining hair density, but due to a slight dip in temple hair, the user switched to dutasteride as an additional measure. Users discuss varying experiences with side effects from finasteride, dutasteride, and minoxidil, highlighting that reactions can differ significantly among individuals.

      community Don’t like the density at all, 2nd hair transplant

      in Transplants  160 upvotes 7 months ago
      The user is unhappy with the results of their second hair transplant, feeling that grafts were wasted on an already transplanted hairline instead of increasing mid-scalp density. They regret stopping medications like Dutasteride, Minoxidil, and RU58841, which led to significant hair loss, and plan to restart them.

      community Serum containing minoxidil and bimatoprost analogs

      1 year ago
      A user discusses using a serum called Dallixa, containing minoxidil-like and bimatoprost-like compounds, for hair loss and greying. The user's dermatologist advised against finasteride and suggested the serum might improve hair pigmentation.