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GlossaryNeurosteroids (neuroactive steroids)

steroids produced in the brain that affect neuron function

Neurosteroids, also known as neuroactive steroids, are a class of steroids synthesized in the brain and nervous system. They play a crucial role in modulating neuronal activity, influencing mood, stress response, and cognitive functions by interacting with neurotransmitter receptors such as GABA and NMDA.

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community 1 Year on Finasteride - Here's what I think

in Finasteride 86 upvotes 5 years ago

A user shared their experience after one year on Finasteride, noting both positive effects on hair retention and minor side effects like reduced libido and high blood pressure. They also emphasized the importance of quitting porn to improve sexual health and mentioned using Viagra to boost confidence.

community Nandrolone Replacement Therapy

in Treatment 41 upvotes 1 year ago

A user discusses starting nandrolone replacement therapy to stop hair loss and improve hair health, noting its benefits over finasteride. They report halted hair loss, improved skin, increased muscle, and a calm mood after three weeks.

community My Experience With Finasteride

in Research/Science 21 upvotes 1 year ago

A user shared their experience with Finasteride for hair loss, noting a significant reduction in DHT levels and a complete loss of libido without other side effects. Another user agreed, discussing the negative impact on sexual drive and criticizing the community's attitude towards discussing side effects.

community The safest way to use finasteride - my research

in Finasteride 23 upvotes 7 years ago

The post discusses microdosing finasteride to minimize side effects while treating hair loss. The user also mentions using minoxidil, biotin, and ketoconazole.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 2 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community What is the real impact of dutasteride on neurosteroids? A little review of 2 scientific datas

in Research/Science 21 upvotes 3 months ago

Dutasteride at 0.5 mg/day does not significantly alter allopregnanolone levels, but higher doses (2.5 mg/day) do. Dutasteride may also have anti-neuroinflammatory effects, but the impact on neurosteroids is still debated.

community Why is Kevin Mann (Haircafe) Hated?

in Chat 62 upvotes 1 year ago

Hair loss treatments, including microneedling, minoxidil, finasteride and RU58841; the efficacy of these treatments; criticisms of Kevin Mann's content related to his selective data presentation and biases towards certain treatments; and other topics such as DHT being labeled a "trash hormone" and critiques of other hairloss YouTubers.

community This community was super helpful to me a while ago, but it feels so good to be off finasteride

in Shaved/buzzed 766 upvotes 11 months ago

The post is about a user who stopped using finasteride for hair loss and shaved his head, receiving positive feedback. The conversation includes discussions on side effects of finasteride, including potential fertility issues, and alternatives like minoxidil, dermarolling, and hair systems.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community Doctor says i shouldn't take fin because its "hormonal"

in Finasteride/Dutasteride 105 upvotes 1 month ago

A user in Turkey was advised by a dermatologist to avoid finasteride due to its hormonal effects and was prescribed minoxidil, shampoo, and vitamins instead. The user is considering seeking another doctor's opinion or buying finasteride directly from a pharmacy.

community Vitamin D3 Supplement for Hair

in Chat 6 upvotes 1 year ago

The conversation discusses recommendations for Vitamin D3 supplements for hair health. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community Why DUT mesotherapy is not considered the best hair loss treatment?

in Treatment 12 upvotes 2 years ago

Dutasteride Mesotherapy for hair loss is discussed, noting its potential to lower scalp DHT without side effects. Concerns include the inconvenience of injections, lack of reputable studies, and availability issues.

community Masseter Muscles and the Tension Theory of Baldness

in Treatment 6 upvotes 4 years ago

The conversation discusses the tension theory of baldness, suggesting that over-developed masseter muscles may harm hair follicles. Botox injections to relax these muscles reportedly led to an 18% increase in hair count in men with AGA.

community I’ve been on oral finasteride/Proscar for 15 years. (AMA)

in Treatment 11 upvotes 2 months ago

A user has been on oral Finasteride/Proscar for 15 years and started using topical Minoxidil, RU58841, and Dutasteride, along with microneedling, 2 years ago. They shared progress pictures and discussed their treatment routine.

community Has anyone ever tried using (all topicals) finasteride + minoxidil + rosemary oil + castor oil + stemoxydine all over the course of a few months/years?

in Treatment 3 upvotes 5 months ago

The user is using topical finasteride and minoxidil for hair loss and is considering adding rosemary oil, castor oil, and stemoxydine to their routine. They are asking if anyone has experience with this combination or a similar one.

community Verteporfin mixing solute for transplants

in Treatment 12 upvotes 9 months ago

Doctors are testing verteporfin topically for healing and potential regeneration after transplants. The user is asking how it is formulated for topical use, such as if it's mixed with a carrier gel.

community RU users hands up I wanna hear your miracolous and horror stories.

in Treatment 44 upvotes 1 year ago

The experiences of users who have used RU58841 to treat hair loss, including both positive and negative effects. Some side effects reported include chest pain, joint pain in the hands, tinnitus, and increased heartbeat.

community Can’t take fin - options/alts?

in Finasteride/Dutasteride 6 upvotes 2 years ago

User seeks non-finasteride hair loss treatments, suggests Eucapil, minoxidil, microneedling, keto shampoo, oral castor oil, and alfatradiol. Reply recommends vitamin D, zinc, pumpkin seed oil, saw palmetto, and high black tea intake, but emphasizes minoxidil and microneedling as most effective.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 317 upvotes 1 month ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community Just popped my first fin, excited as hell!

in Finasteride/Dutasteride 154 upvotes 4 months ago

A user shared their excitement about starting finasteride for hair loss after trying various ineffective methods. Other users discussed their experiences with finasteride, including shedding phases and side effects, with one mentioning using topical finasteride and minoxidil.

community Neck tension, and hair loss, I am 100 percent sure that there is a connection

in Treatment 19 upvotes 4 months ago

The user believes neck tension and poor posture contribute to hair loss, noticing improvements with yoga and muscle relaxation. Replies suggest androgenic alopecia as the cause and recommend exercises.

community Possible explanation of why Dutasteride seems to be worse for some people’s hair.

in Treatment 47 upvotes 1 year ago

The conclusion of the conversation is that some individuals may experience a condition called reactionary hypergonadism when taking dutasteride for hair loss. This condition can lead to an increase in testosterone levels, which may worsen hair loss instead of improving it.

community I find it crazy how some people like this bloke have 0 DHT sensitivity. He is on grams of anabolic steroids and has a full, thick head of hair. I wish all of on here had this guys hair genes lol

in Satire 443 upvotes 1 year ago

The conversation is about hair loss and the possibility of maintaining a full head of hair while using anabolic steroids. Some users believe that having good hair genes and taking hair loss protocols can help prevent hair loss while on steroids.

community HairCafe: The Broscience of Hair Loss, DHT, and Bludflow with Andrew Huberman

in Chat 1 year ago

Hair loss, DHT and bloodflow with Andrew Huberman; the discussion includes opinions about supplements, finasteride, minoxidil, turmeric, coffee and botox injections for hair loss.

community I don’t even care about my hair I just like taking drugs

in Satire 1 year ago

A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.

community I’ve been shaving my head for 15 years. Is there anything out there that can truly regrow hair?

in Hair Systems 1 year ago

A user who has been shaving his head for 15 years looking for potential treatments to regrow hair; the replies range from advice to try out medications such as finasteride and minoxidil, to suggestions of changing up his look with facial hair or hobbies.

community The no BS guide to saving your hair without finasteride (improvement in 90% of patients in the study) with a low side effect profile or improvement in 100% of patients but a higher side effect profile and increased dosage. The future is here?

in Minoxidil 92 upvotes 4 years ago

Hair loss treatments, specifically the use of oral minoxidil in combination with micro-needling. Oral minoxidil has been found to improve hair density in 90% of patients with a low side effect profile, but using 5mg per day can result in higher side effects including hypertrichosis and edema. Other treatments mentioned include finasteride and RU58841.

community Finasteride and Its Effects on Cognition: Where's the Science?

in Research/Science 28 upvotes 4 years ago

The user shared their experience with hair loss treatments, including low-dose minoxidil, finasteride, and essential oils, and expressed concerns about the cognitive side effects of finasteride. They are seeking more information on how finasteride may affect cognition and are considering whether to continue or stop the treatment.

community Finasteride 1 mg daily vs Dutasteride 0.5 mg daily

in Treatment 10 upvotes 6 months ago

Switching from finasteride 1mg daily to dutasteride 0.5mg daily may offer better hair regrowth. However, if finasteride is effective, fully switching to dutasteride is not advised; instead, adding dutasteride once a week could be beneficial.

community 42 Year Old 12 month finasteride, minoxidil, dermapen, nizoral

in Progress Pictures 331 upvotes 2 years ago

42-year-old used finasteride, minoxidil, dermapen, and nizoral for 12 months, achieving significant hair growth. Consistency and patience are important for success.