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      community Any experiences with Ptd-dbm??

       8 upvotes 3 months ago
      The user experienced reduced hair loss using an online serum but found it too expensive and is seeking a vendor for ptd-dbm. They are also interested in KY19382 but are unable to find it.

      community Mesenchymal Stem Cell Therapy (Exosome) Before & After

       2 upvotes 2 years ago
      A user's father experienced hair regrowth and other health improvements after two IV exosome treatments. The user also had four rounds of exosome therapy, noting significant hair regrowth and relief from headaches, but no change in gray hair.

      community Black market pp405? Title title

      in Treatment  8 upvotes 8 months ago
      PP405 is likely fake, and JXL069 is an unrefined prototype with unknown side effects. It's advised to wait for the official PP405 release.

      community Why My Discipline Can't Beat My "Watery Belly" on Finasteride

      1 year ago
      A user experienced a "watery belly" and cellulite after starting finasteride, despite maintaining a disciplined fitness routine. Others suggest checking hormone levels, as changes in DHT and estrogen could affect fat metabolism, but age might also be a factor.

      community M35 diffuse thinning, sudden realization after collaging old pic

       11 upvotes 6 days ago
      The user experienced hair regrowth after starting finasteride in September 2025 and topical minoxidil in December 2025, despite setbacks from using tretinoin gel. Their current treatment includes dutasteride, finasteride, topical minoxidil, and dermastamping.

      community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?

      in Chat  45 upvotes 8 months ago
      Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Severe diffuse thinning since 13 years old

      in Treatment  6 upvotes 1 year ago
      A 15-year-old experiencing severe diffuse thinning plans to use minoxidil, dermarolling, and possibly ketoconazole, with hopes to later incorporate finasteride. Concerns about starting finasteride too young and the need for a dermatologist consultation are discussed.

      community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

       129 upvotes 3 years ago
      The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

      community how to make dut pills from dut powder

      7 months ago
      A user discusses making DIY dutasteride capsules from powder bought from China, using a mix of MCT oil and propylene glycol. Others warn about the risks of incorrect dosing, potential degradation, and the possibility of receiving fake products.

      community Lets do this!!! My current Stack

      in Treatment  4 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen using Alfatradiol, Pyrilutamide, and Minoxidil. The user shares their current stack of these treatments.

      community Thin roots but thick ends hair – anyone else facing this?

      in Treatment  5 upvotes 5 months ago
      A 23-year-old is experiencing hair that is thick at the ends but thin at the roots despite using minoxidil and finasteride for 10 months. They are concerned about whether this is normal or a sign of miniaturization and seek advice on reversing or improving the condition.

      community Survived the 2nd shedding phase. 7mos progress.

       42 upvotes 11 months ago
      The conversation is about hair loss treatment progress using oral finasteride, topical minoxidil, and microneedling. Users discuss experiencing shedding phases and the importance of trusting the process for hair regrowth.

      community Homemade pyri solution- problems

      in Treatment  1 upvotes 2 years ago
      A user mixed a pyrilutamide solution and noticed undissolved powder at the bottom, questioning if this is normal and how long to wait before applying it. They wished others good luck with their treatments.

      community Is diffuse thinning even treatable?

       18 upvotes 1 week ago
      The user has been using finasteride and oral minoxidil for two years without improvement in diffuse thinning and is considering switching to dutasteride and getting a scalp biopsy. Suggestions include treating subclinical hypothyroidism, trying PRP therapy, and checking for autoimmune issues.

      community Second shed, second shed, Second shed

       4 upvotes 2 years ago
      The user experienced hair loss after initially seeing positive results from using dutasteride and oral minoxidil. They are concerned about the hair shedding and wonder if stopping a multivitamin contributed to the issue.

      community Pyrilutamide / KX-826 | Discussion EU

       4 upvotes 3 years ago
      The conversation is about a user expressing concerns over the safety of a new drug called Pyrilutamide (also known as KX-826) for hair loss. The user will only trust the drug if it's permitted by EU regulations and sold by a reputable company.

      community Before and after adding pyrilutamide and alfatrodial

       67 upvotes 5 months ago
      A user shared their experience with hair loss treatments, using minoxidil, pyrilutamide, alfatrodial, and nizoral to improve hair density and thickness. They reported positive results without side effects and emphasized the importance of consistency with topical treatments.

      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

       23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Topical finasteride making. Powder not disolving

       4 upvotes 3 years ago
      OP is trying to dissolve finasteride powder for a topical solution but faces issues with it not dissolving properly in ethanol or water. Users suggest methods like using a magnetic stirrer, shaking the mixture, or filtering out fillers, with some noting that finasteride is soluble in alcohol.