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    GlossaryMelatonin Receptor 1 (Mel1a)

    regulates sleep-wake cycles by binding to melatonin

    Melatonin Receptor 1 (MT1) is a protein found in various tissues in the body that binds to melatonin, a hormone primarily released by the pineal gland that regulates sleep-wake cycles. This receptor plays a crucial role in mediating the effects of melatonin on circadian rhythms and seasonal biological processes.

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      community Is anyone using melatonin for hair loss?

      in Research/Science  9 upvotes 5 months ago
      Melatonin is being discussed as a potential treatment for hair loss, with questions about its effectiveness and whether it should be used topically or orally. No specific conclusions or personal experiences were shared.

      community Melatonin options for Europe??? *Retrograde Alopecia*

      in Product  3 upvotes 6 months ago
      A user is considering using melatonin for hair recovery on the side and neck area but is unsure about the best options in Europe and whether a dietary supplement form can be applied to the scalp. They found a product but are hesitant and seeking opinions on its use for alopecia.

      community Optimal dose for topical Melatonin

      in Treatment  6 upvotes 1 year ago
      The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

      community Compounding Topical Melatonin at Home

      in Treatment  7 upvotes 3 years ago
      Melatonin at a 0.0033% concentration shows results for hair loss when used topically. A user is discussing how to replicate this by adding 2mg of Melatonin to 60ml of Minoxidil solution.

      community Melatonin a possible tool to help fight AGA hair loss.

      in Research/Science  54 upvotes 3 years ago
      Topical melatonin may help reduce hair loss and increase hair thickness in people with androgenetic alopecia (AGA), with some studies showing positive results. It can be mixed with minoxidil for application, and its effectiveness might be enhanced when used with micro-needling, but results may vary among individuals.

      community Topical Melatonin for mild aga

      in Chat  2 upvotes 8 months ago
      The conversation is about an 18-year-old male considering topical finasteride for hair loss and asking about the effectiveness of topical melatonin for hair regrowth and density. No specific treatments were confirmed to be used.

      community Diluting Melatonin Sublingual Spray

      in Treatment  2 upvotes 1 year ago
      A user wants to dilute a melatonin sublingual spray to 0.0033% for use as a topical hair loss treatment. They ask if distilled water can be used for dilution and how much is needed for stability over months.

      community Topical melatonin instead of fin

      in Research/Science  8 upvotes 1 year ago
      A 22-year-old man has been using topical melatonin for a year to slow hair loss and it appears to be effective. He's seeking alternatives to finasteride due to potential side effects, and is interested in understanding how melatonin works to prevent hair shedding.

      community Topical melatonin/cetirizine instructions

      in Treatment  19 upvotes 1 year ago
      User shares a topical hair loss solution using melatonin and cetirizine to help reduce shedding and itching. Instructions provided for creating and using the mixture, with additional lifestyle tips for overall hair health.

      community Does melatonin dissolve in isopropyl alcohol

      in Technology  6 upvotes 1 year ago
      The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

      community Topical melatonin/oral

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses the potential positive effects of melatonin on hair growth. The original poster plans to try both oral and topical melatonin and is seeking recommendations for a good source.

      community Tropical Melatonin??

      in Product  7 upvotes 3 years ago
      The conversation is about the effectiveness of topical melatonin for hair loss. No specific treatments were discussed, only a sarcastic suggestion to go to tropical places and eat coconuts.

      community Have you guys heard about topical melatonin?

      in Research  7 upvotes 4 years ago
      Topical melatonin may improve hair density and thickness, and reduce hair loss and seborrhea with no significant side effects. The user made their own melatonin solution for hair treatment.

      community Anyone tried topical melatonin?

      in Treatment  4 upvotes 3 months ago
      The conversation is about using topical melatonin for hair retention and its potential effectiveness alongside minoxidil. The user explicitly does not want advice about finasteride.

      community Finasteride + topical melatonin + rosemary oil for regrowth

      in Treatment  1 upvotes 4 months ago
      The user has been using finasteride for 4 months with positive results, including thicker and darker hair. They are seeking advice on maximizing hair growth without minoxidil, using a routine that includes finasteride, rosemary oil, argan oil, topical melatonin, specialized shampoos, and vitamins.

      community Anybody using topical melatonin or zix in 2024?

      in Chat  12 upvotes 5 months ago
      The conversation is about using topical melatonin or zix for hair loss without affecting hormones. The user is seeking advice on which treatment is more effective.

      community best way make topical melatonin solution

      in Treatment  7 upvotes 5 months ago
      A user wants to try melatonin for hair loss by mixing melatonin powder with a topical oil serum. They are asking if this mixture is possible and effective.

      community How to make topical melatonin?

      in Treatment  1 upvotes 7 months ago
      The conversation is about creating a topical melatonin treatment for hair loss. Specific treatments discussed include Minoxidil, Finasteride, and RU58841.

      community Any topical melatonin users here ?

      in Treatment  6 upvotes 2 years ago
      The conversation discusses using topical melatonin for diffuse thinning and mentions treatments like Minoxidil, finasteride, and RU58841. The user is seeking advice on whether melatonin could help with their condition.