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    GlossaryLymphoepithelial Kazal-type-related Inhibitor (LEKTI)

    protein regulating skin and hair enzyme activity

    Lymphoepithelial Kazal-type-related Inhibitor (LEKTI) is a protein that plays a crucial role in regulating the activity of certain enzymes involved in skin and hair health. It acts as a serine protease inhibitor, helping to maintain the integrity of the skin barrier and prevent excessive inflammation. Mutations in the gene encoding LEKTI can lead to skin disorders such as Netherton syndrome, which is characterized by red, scaly skin and hair abnormalities.

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      community People here just don't know what they are letting themselves in for!

      in Chat  125 upvotes 8 months ago
      The conversation discusses hair loss treatments, emphasizing the importance of patience and sticking with a treatment for at least 12-18 months before judging its effectiveness or adding new treatments. Users share experiences and agree that introducing treatments too quickly can lead to panic and negative outcomes.

      community Transformation from balding to…

      in Progress Pictures  1857 upvotes 1 year ago
      The user, Lofi-luu, shared their transformation from balding to having a full head of hair after getting a hair transplant and using finasteride for almost 2 years. They also discussed their workout routine and emphasized the importance of not letting balding hold them back in life.

      community Losing hair as teenager Dont know what to do

      in Chat  3 upvotes 1 year ago
      A teenager started balding at 13 and has been using minoxidil for 2 years, but the hair loss is returning. They are seeking advice on additional treatments. Another user suggests finasteride or shaving the head, and emphasizes the importance of not letting hair loss affect self-esteem and relationships.

      community DUT Risk profile for having kids?

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

      community PSA: Don't buy cheap toppik off ebay

       8 upvotes 7 years ago
      Cheap Toppik from eBay is likely fake and doesn't stick well to hair. Buy from official website for better quality.

      community Ashton Kutcher talking about Avodart/Dutasteride on national television

       109 upvotes 5 years ago
      How actor Ashton Kutcher used Dutasteride (Avodart) to treat his hair loss at age 25, but stopped taking it due to potential side effects when he wanted to have kids; and the discussion of various treatments for hair loss such as finasteride, minoxidil, and RU58841.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 1 year ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community 4 months minox + fin +microneedling

      in Progress Pictures  336 upvotes 1 year ago
      A user's progress with treating hair loss, using minoxidil, finasteride and microneedling. The user experienced impressive results after four months of treatment, and mentioned that stopping recreational drugs and losing weight helped their hair regrowth.

      community Using another shampoo immediately after nizoral

      in Ketoconazole  10 upvotes 3 years ago
      The conversation is about using another shampoo after Nizoral to improve hair appearance without reducing ketoconazole's efficacy. Users also discuss adding coconut oil to Nizoral to prevent hair dryness.

      community now exactly 2 years since starting 1mg oral fin

      in Progress Pictures  747 upvotes 1 month ago
      The user experienced significant hair regrowth using 1mg oral finasteride daily and recently added minoxidil 5% to address remaining gaps. They reported no significant side effects, attributing any perceived changes to weight fluctuations rather than the medication.

      community Sometimes, the problem is the hair structure…

      in Progress Pictures  165 upvotes 2 months ago
      A 24-year-old shared his hair loss journey, using finasteride and topical minoxidil for 6 months with positive results and no side effects. He recommends growing hair out and getting a good haircut to improve appearance and confidence.

      community 4 month progress on treatment! Low dose fin.

      in Progress Pictures  179 upvotes 2 months ago
      User shared 4-month progress on hair loss treatment using 0.25mg finasteride daily and topical minoxidil daily, noting cognitive decline possibly linked to finasteride. Users discussed side effects, alternative treatments, and shared similar experiences.

      community How do I layer multiple treatments?

      in Treatment  2 upvotes 3 months ago
      The user asks about the order and compatibility of using topical minoxidil, stemoxydine, The Ordinary natural moisturizing factors + HA for scalp, RU58841, and Nioxin system 2 leave-in treatment. They seek advice on layering these hair loss treatments.

      community 20m /// 3 month progress pictures

      in Progress Pictures  64 upvotes 4 months ago
      A user shared their 3-month hair loss progress using 5% topical Minoxidil, 8% topical RU58841, 1mg Finasteride daily, and a 1.5mm derma stamp weekly. Another user commented that the results look improved.

      community 1Y & 5 month on Fin, 8 Months Min Help!

      in Progress Pictures  10 upvotes 6 months ago
      The user has been on finasteride for 1 year and 5 months and minoxidil for 8 months to treat hair loss, and is considering using dutasteride due to recent shedding and dissatisfaction with their current finasteride manufacturer. They also micro-needle every 2 months and are noticing more baby hairs despite concerns about receding.

      community Sharing my 3.5 year journey, keep grinding guys

      in Progress Pictures  228 upvotes 7 months ago
      The user shared a 3.5-year hair loss treatment journey using 1 mg finasteride daily and minoxidil foam, noting significant improvement, especially in the third year. They also mentioned using Nizoral shampoo twice a week and supplements like vitamin D3, biotin, and omega 3 and 6.

      community Scalp Inflammation is eating my hair!

      in Chat  26 upvotes 7 months ago
      A user with seborrheic dermatitis is experiencing bald spots and hair thinning despite changing their diet and taking oral minoxidil. Another user suggests using ketoconazole shampoo properly, using a scalp massager, applying rosemary/peppermint oil, keeping hair short, and taking fish oil to improve scalp health.

      community 3 months on topical min and around 6 months on oral fin

      in Progress Pictures  112 upvotes 8 months ago
      The user is discussing their hair loss treatment progress, using topical Minoxidil, oral Finasteride, derma stamping, and Ketoconazole shampoo. Some replies express skepticism about the results, while others show support or comment on the presentation of the progress pictures.

      community Just started my third month of fin min

      in Treatment  148 upvotes 9 months ago
      A user, aged 32, is treating hair loss with oral finasteride, topical minoxidil, Vitamin D3, and magnesium. They shave their head, condition daily, and wash their hair every three weeks.

      community Day 11- I have removed all Scabs

      in Progress Pictures  239 upvotes 9 months ago
      Eleven days after a hair transplant, the user has removed all scabs and plans to resume Oral Dutasteride and Oral Minoxidil. They will also start using a serum provided by the clinic and are sharing progress and clinic information privately to avoid negative comments.

      community What if I told you you could have it all back? May 2023 to now

      in Progress Pictures  155 upvotes 11 months ago
      The conversation is about a user's 7-month hair regrowth progress using finasteride/minoxidil gel, minoxidil foam, ketoconazole shampoo, thickening shampoo and conditioner, biotin supplements, and plans to start using a dermaroller. Replies suggest a new haircut and commend the user's progress.

      community C’est terrible - at my wits end

      in Female  441 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community 1 Month Topical Minoxidil Only

      in Progress Pictures  72 upvotes 1 year ago
      The conclusion of the conversation is that the user plans to use topical minoxidil, ketoconazole shampoo, and a derma stamp for hair loss treatment. They also plan to start using finasteride in the next 2 months. Other users suggest using finasteride and a hair transplant for better results. The user appreciates the feedback and will continue posting progress.

      community How much do you guys think diet and sleep affects results?

      in Research/Science  37 upvotes 1 year ago
      The conversation discusses whether lifestyle factors like diet and sleep affect hair growth in people with reversible hair loss. Some believe these factors, along with treatments like minoxidil, finasteride, and RU58841, can improve hair health, while others argue hair loss is mostly determined by genetics and DHT sensitivity.

      community How To Use Tretinoin + Minoxidil Together

      in Minoxidil  9 upvotes 1 year ago
      The conversation is about the correct method of applying tretinoin and minoxidil together for hair loss, including which to apply first, waiting times, and frequency of use. It also questions whether the approach to using tretinoin on the scalp should be similar to its application on the face.

      community Shaving is NOT accepting baldness

      in Shaved/buzzed  52 upvotes 1 year ago
      Accepting baldness and the various ways people try to cope with it, such as shaving, using medications like minoxidil and finasteride, or getting a hair transplant. Participants discussed how true acceptance of hair loss involves confronting difficult emotions such as grief for one's former appearance and identity, as opposed to simply superficially hiding it with a shaved head.
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