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Glossary Juri Flap

surgical technique rotating scalp flap for hair restoration

The Juri Flap is a surgical technique used in hair restoration, particularly for treating male pattern baldness. It involves the rotation of a flap of hair-bearing scalp from the side of the head to the balding area at the front. This method provides immediate hair coverage and can create a natural-looking hairline, but it requires careful planning and expertise to ensure proper blood supply and minimize complications.

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community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

4 upvotes 2 years ago

The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.

community What vehicle is being used in the breezula trial?

in Research/Science 5 upvotes 2 years ago

The conversation is about identifying the vehicle used in the Breezula (clascoterone) trial for hair loss. No specific treatments were mentioned.

community Clascoterone vs fluridil, and using them with minoxidil

6 upvotes 1 year ago

The user is considering minoxidil, clascoterone, and fluridil for hair loss, avoiding finasteride and RU58841. They are also contemplating a hair transplant and exploring the resilience of transplanted hair without finasteride.

community Just started my first vial of fluridil

4 upvotes 3 years ago

Fluridil was discussed as a hair loss treatment, with some users experiencing side effects like lethargy and chest tightness. Users also mentioned other treatments like RU58841 and finasteride, with mixed opinions on their effectiveness.

community RU58841 in germany eventually facing legal charges

in Hair Systems 32 upvotes 1 year ago

The conversation discusses the use of RU58841 for hair loss, with concerns about its legality in Germany and potential legal consequences. Alternatives like finasteride and dutasteride are mentioned, with some users questioning the effectiveness and safety of RU58841.

community Fluridil (Eucapil) seems like a great option?

4 upvotes 9 months ago

The user stopped using finasteride due to side effects and is considering Fluridil (Eucapil) as an alternative for hair loss treatment. They are exploring other options like RU58841 and are interested in the experiences of others with Fluridil, noting its good safety profile despite the cost.

community The final nail in the coffin. PP405 is confirmed JXL069.

440 upvotes 1 month ago

PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.

community Is fluridil cost-efficiency absolute garbage?

in Product 1 upvotes 2 years ago

Fluridil is considered safe with moderate effectiveness for hair loss, but its cost of €50 per month is seen as high compared to other treatments. The user is considering Pyri as a more cost-effective option and is seeking success stories about Fluridil's ability to stop hair loss without side effects.

community Why are there no proper phase 3 trials for RU

in Chat 4 upvotes 6 months ago

RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

community Anyone try RU58841 from this brand? truth진실

4 upvotes 1 year ago

The conversation discusses skepticism about the effectiveness and formulation of a $10 RU58841 gel from a Korean brand, questioning if ethanol is used to hold the active compounds. Concerns are raised about the feasibility of selling it at such a low price.

community Eucapil, Fluridil update from manufacturer

4 upvotes 1 year ago

The user is experiencing hair loss after a hair transplant and is considering using fluridil (Eucapil) and possibly alfatradiol as treatments, as they couldn't tolerate finasteride or minoxidil. The manufacturer of Eucapil confirmed they won't produce higher concentrations due to lack of efficacy.

community What's people's thoughts on Fluridil in 2023

6 upvotes 2 years ago

Fluridil is discussed as a potential topical alternative for hair loss for those experiencing side effects from finasteride. Some people have tried higher concentrations, but there's no clear consensus on its effectiveness.

community RU58841 longterm use and expectations.

5 upvotes 4 months ago

RU58841 has been used by a person for 5 years, effectively regrowing and maintaining hair without noticeable side effects, though there are concerns about potential long-term risks. The user initially tried finasteride but did not achieve the desired results.

community Jxl069 (pp405 api) week 8 update

205 upvotes 1 year ago

The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

community RU58841 once vs twice daily? Is once a day effective enough?

1 upvotes 5 months ago

RU58841 is effective when used once daily. Using it twice daily may require reducing the dosage, potentially decreasing its effectiveness.

community Did we have some news from Breezula ?

7 upvotes 10 months ago

Breezula results are awaited, but no updates have been posted. Users are uncertain about its promise.

community Pyrludimide (KX-826) or Breezula (clascoterone)

9 upvotes 5 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community RU58841 is a scam until proven otherwise

15 upvotes 1 month ago

RU58841 is considered ineffective as a standalone treatment for hair loss, with users often combining it with finasteride and minoxidil for potential benefits. Many users report mixed results and concerns about side effects, leading to skepticism about its efficacy.

community Clascoterone for hair loss. Promising study.

11 upvotes 9 months ago

A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

community Fluridil solution at Actifolic

5 upvotes 3 years ago

Fluridil, also known as Topilutamide or Eucapil, is discussed as a treatment for hair loss. It is noted as an androgen receptor antagonist, not a vasodilator.

community Breezula disappearing like my hair follicles.

8 upvotes 6 months ago

Breezula's development has stalled, leaving users disappointed. The conversation includes skepticism about its approval and effectiveness.

community This could be it!!! New treatment increase hair 500%

340 upvotes 9 months ago

Clascoterone (Breezula) shows a potential 500% increase in hair growth, possibly outperforming minoxidil and finasteride. It is in advanced trials, with hopes for FDA approval, but cost and side effects are concerns.

community Why was fluridil abandoned and never made past phase 2?

5 upvotes 4 years ago

Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.

community Actifolic RU58841 and others Scam?

5 upvotes 3 years ago

Actifolic's RU58841 and Pyri products are perceived as ineffective, with users reporting no side effects or improvements, suggesting possible quality issues. Users recommend alternative sources and emphasize the importance of timing when using RU58841 with Minoxidil.

community Joining clinical study for Clascoterone (Breezula)

in Research/Science 7 upvotes 1 year ago

The conversation is about a user considering joining a clinical study for Clascoterone (Breezula) after experiencing no results with topical finasteride and minoxidil, and side effects from oral finasteride. The user is seeking advice on clinical study participation and experiences.

community Ru58841 long term users efficacy

17 upvotes 4 months ago

RU58841 is effective for long-term hair loss treatment, often used with finasteride or dutasteride for better results. Users report varying experiences with side effects and effectiveness, with some noting improvements and others experiencing shedding or needing to adjust dosages.

community Question about RU58841 reason it wasn't continued

5 upvotes 1 month ago

RU58841 is debated for hair loss treatment; some users report positive results, while others find it ineffective or risky. It is not widely marketed due to limited effectiveness, safety concerns, and competition from existing treatments like finasteride and minoxidil.

community How exactly is Eucapil (fluridil) approved in Europe?

in Product 6 upvotes 3 years ago

Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Eucapil (fluridil) is approved as a cosmetic hair-care agent in Europe, but users question the level of testing required for approval.

community Pelage will be presenting PP405 at the Masters of Aesthetics which is held from 28-30th August

in Chat 32 upvotes 1 month ago

The conversation expresses skepticism about the effectiveness of new hair loss treatments, comparing them to 2% minoxidil and criticizing the lack of substantial data. Users doubt the claims of a non-hormonal treatment and mention previous disappointments with products like JXL-069.

community Anyone who used RU58841 without fin/dut?

in Product 1 upvotes 1 year ago

RU58841 was used by some for hair loss, but concerns about side effects like gynecomastia and safety were raised. Alternatives like finasteride, minoxidil, pyrilutamide, and alfatradiol were discussed, with some users reporting better experiences with these treatments.