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Did you mean IGF-1 Receptor?

GlossaryIGF-1 Receptor

protein on cell surfaces that binds to growth hormone IGF-1

The IGF-1 Receptor (Insulin-like Growth Factor 1 Receptor, IGF1R) is a protein found on the surface of human cells that binds to the hormone IGF-1. This interaction plays a crucial role in cell growth, development, and survival. In the context of hair biology, IGF-1 and its receptor are important for hair follicle development and the regulation of hair growth cycles.

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community Pyrilutamide - your experience?

in Product 12 upvotes 1 year ago

The conversation is about the lack of improvement in hair loss after using Pyrilutamide for 14 weeks, with the original poster unable to use Finasteride due to depression. Replies suggest that Pyrilutamide, like RU58841, may not work for everyone, and a more potent drug is being developed by Kintor.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 1 year ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community When someone posts a scalp tension theory

in Satire 267 upvotes 3 years ago

Hair loss theories discussed include poor blood flow, scalp tension, inflammation, and DHT. Treatments mentioned are massaging scalp, minoxidil, finasteride, and RU58841.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community Why is nobody studying the difference between donor and balding hair?

in Chat 89 upvotes 5 months ago

The conversation discusses why the difference between donor and balding hair isn't studied more to find a cure for hair loss. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Signs of life. Ru, topical fin/min, mk677, micro needling

in Progress Pictures 192 upvotes 3 years ago

The conversation discusses using RU58841, topical finasteride/minoxidil, MK677, and microneedling as treatments for hair loss. MK677 is mentioned as a growth hormone that improves hair health and recovery from microneedling.

community Sandalore: a scientific homemade approch

20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community TDM-105795, a new hair loss treatment that actually works!

in Treatment 44 upvotes 9 months ago

A new hair loss treatment called TDM-105795 is discussed as a potential replacement or add-on to Minoxidil. Users express hope for new effective treatments.

community High DHT with finasteride. Help!

in Finasteride/Dutasteride 6 upvotes 9 months ago

Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

community My hair after 3 steroid cycles

in Progress Pictures 25 upvotes 4 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community Is this broscience? From More Plates, More Dates

in Research/Science 22 upvotes 8 months ago

The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

community Natural Remedies: Polyphenols and Hair Loss

19 upvotes 5 years ago

Natural remedies to treat hair loss, such as polyphenols, apple peel extract, grape seed extract, green tea extract, peppermint oil, pumpkin seed oil, apigenin, Ginkgo biloba, red clover extract, olive leaf extract, Ecklonia Cava and Grateloupia elliptica. In addition, terpenes, carotenoids, and tocopherols were discussed as potential treatments.

community Solving Hair Loss with Research at MIT

in Research/Science 590 upvotes 1 month ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community My hairloss journey. Minox at 34, transplant at 38. No Finasteride

in Transplants 267 upvotes 8 months ago

A person started using Minoxidil at 34 and had a hair transplant at 38, avoiding a straight hairline for a natural look and had 2200 grafts. They began taking Finasteride as a precaution, but Minoxidil did most of the work.

community Does Finasteride Sustain Minoxidil-grown Hairs?

in Finasteride/Dutasteride 8 upvotes 1 year ago

The post discusses whether finasteride can maintain hair growth stimulated by minoxidil. The response indicates that finasteride cannot sustain minoxidil-grown hairs.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 44 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Actor Paul Mescal, 26, has a receding hairline. I thought it was pretty cool to see a younger actor being successful, despite dealing with hair loss. He just got nominated for an Oscar.

in Chat 353 upvotes 1 year ago

Actor Paul Mescal, who has a receding hairline, and how it affects his success in the entertainment industry. People discussed how styling can help disguise hair loss, and that hair loss doesn't necessarily mean one's appearance is immediately ruined. Treatments such as Minoxidil and Finasteride were mentioned to combat hair loss.

community Trichotest results in… min not on my list! Just Fin/Dut, Zinc… and the insanely expensive latanoprost & prostaquinon.

in Technology 22 upvotes 2 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community 8 month update. Topical fin/min, topical dut, mk677, RU, micro needling

in Progress Pictures 218 upvotes 3 years ago

User shared 8-month hair loss treatment progress using topical fin/min, topical dut, mk677, RU, and microneedling. They experienced watery semen as a side effect but saw significant improvement in hair growth.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 135 upvotes 2 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community Does whey protein and creatine aggravate hair loss?

in Research/Science 82 upvotes 11 months ago

The conversation discusses whether whey protein and creatine worsen hair loss. Some users report hair loss with creatine use, while others do not; opinions on whey protein's effects are mixed. Treatments mentioned include PRP, minoxidil, and finasteride.

community 48 Days Fin, Min, and Derm Part 2

in Progress Pictures 264 upvotes 1 year ago

The user discussed their positive experience with hair loss treatments Finasteride, Minoxidil, and Dermarolling, showing significant progress in 48 days. Other users expressed interest in trying these treatments, asked about side effects, and one noted that they've observed good results in black people.

community Soo.. uhh.. one year... wondering when Dutasteride is going to stop hair loss

in Finasteride/Dutasteride 132 upvotes 1 year ago

User has been on finasteride and switched to Dutasteride 6 months ago, using minoxidil, tretinoin, microneedling, and RU-58841, but still experiencing hair loss. Advice given includes waiting 6-18 months for Dutasteride results and checking if it's definitely MPB.

community I don’t even care about my hair I just like taking drugs

in Satire 1 year ago

A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.

community Two months of dutasteride once a day 0.5 and minoxidil 5% twice a day. The light is different but I think there is progress

in Is this regrowth? 96 upvotes 1 year ago

A user's experience with taking dutasteride and minoxidil for hair loss, with other users providing advice to continue treatment for at least 12 months and including dermarolling as well as dietary changes.

community M26 - 9 months after hair transplant! AMA

in Transplants 624 upvotes 4 years ago

A user who underwent a hair transplant in Istanbul to reduce balding, and the discussion of various treatments such as finasteride and growth hormone for preventing further hair loss.

community Is IGF-1 the reason why some people don't respond well to min-fin treatment?

in Treatment 6 upvotes 9 months ago

A user who didn't respond well to minoxidil and finasteride is considering the role of IGF-1 in hair loss treatment effectiveness. They discuss the potential of using HGH to improve hair growth and other health issues, referencing several sources that suggest IGF-1 levels may influence hair loss and treatment response.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 3 weeks ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

community Is there any point to microneedling if you're on oral minoxidil?

in Microneedling 45 upvotes 1 year ago

Microneedling's effectiveness for hair regrowth is debated, with mixed results from studies. Some believe it helps with blood flow and scalp health, while others see it as largely ineffective.