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Did you mean Genetic Polymorphisms?

GlossaryGenetic Variants (Genetic Polymorphisms)

differences in DNA sequence among individuals

Genetic variants, also known as genetic polymorphisms, are differences in the DNA sequence among individuals. These variations can affect how genes function and can influence traits such as hair color, susceptibility to diseases like alopecia, and response to medications. While some genetic variants have no impact on health, others can be significant in understanding genetic predispositions and developing personalized medical treatments.

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community Huberman tweet about finasteride

in Finasteride/Dutasteride 278 upvotes 10 months ago

The conversation is about the side effects of finasteride, including Post Finasteride Syndrome, with varied personal experiences and differing views on the credibility of information sources. Some participants also discuss using minoxidil as a hair loss treatment.

community An argument for why we should take topical Dutasteride seriously

in Research/Science 85 upvotes 3 years ago

Topical Dutasteride may halt hair loss and effectively treat androgenic alopecia. Combining low-dose oral Dutasteride with topical application could maximize regrowth and minimize side effects.

community My 3 year experience and progress pics with 6 different treatments

in Progress Pictures 39 upvotes 4 years ago

The user tried Finasteride, Dutasteride, Minoxidil, RU58841, dermarolling, and oral castor oil for hair loss. They found RU58841 and Minoxidil most effective with no side effects, while Finasteride and Dutasteride caused sexual side effects.

community Maintaining hair until Breezula without Fin

in Treatment 6 upvotes 4 years ago

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 41 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Dutasteride Literally Saves Your Hair

in Finasteride/Dutasteride 97 upvotes 3 months ago

Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.

community Why does it seem everyone favors finasteride over dutasteride?

in Female 62 upvotes 5 months ago

The conversation discusses preferences for hair loss treatments, specifically finasteride over dutasteride. Users share personal experiences, cost considerations, FDA approval status, and potential side effects, with some switching between treatments to find what works best for them.

community 8-9 Month Update. 24M Korean Diffuse Thinner

in Progress Pictures 311 upvotes 8 months ago

The conversation discusses a 24-year-old Korean man's progress with hair loss treatments over 8-9 months, with specific treatments not mentioned due to redacted information. Users are commenting on the effectiveness and inquiring if Asians have better results with hair loss treatments.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 13 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Genetic testing to determine individualized hairloss treatment?

in Research/Science 10 upvotes 1 year ago

A user discusses a company, Roots by Genetic Arts, that offers a genetic test for hair loss to create personalized treatments, and is curious about its legitimacy and the science behind it. The company tests 16 genes related to hair loss and compounds a topical treatment based on the results.

community Is Fagron TrichoTest (first genetic test for hair loss) a SCAM?

in Research/Science 8 upvotes 1 year ago

User ronopibf discusses Fagron TrichoTest, a genetic test for hair loss, and seeks opinions on its effectiveness. Some users support the service, while others call it a scam, with prices ranging from $200-$500.

community DNA Testing by Roots by Genetic Arts

in Research/Science 3 upvotes 6 months ago

A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

community The closest thing to a cure before hair cloning or genetic via?

in Treatment 9 upvotes 1 year ago

The conversation discusses using finasteride or dutasteride to reduce DHT, CosmeRNA to target androgen receptors, and Minoxidil as a vasodilator for hair growth. The regimen aims to maintain hair by addressing DHT-AR ratio and continuous Minoxidil use.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 102 upvotes 2 days ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community Vegan Protein Powder Make Loss Worse?

in Female 2 upvotes 1 month ago

A user is experiencing genetic hair loss and is using spironolactone and minoxidil without success. They are considering switching to vegan protein powder due to digestive issues and are concerned if it will worsen hair loss.

community Welcome to Tressless, OG! Ötzi was dark-skinned and balding.

in Chat 11 upvotes 1 year ago

The conversation discusses that genetic analysis of the Iceman Ötzi shows he had male-pattern baldness and dark skin, with a joke about using beards and tattoos to distract from hair loss. No specific hair loss treatments are mentioned.

community How does hair loss and recovery work?

in Chat 12 upvotes 3 weeks ago

Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

community 29f Female on Dutasteride Progress.

in Female 14 upvotes 10 months ago

A 29-year-old woman with genetic hair loss started using 0.5 dutasteride a week ago and has noticed increased shedding, no sexual side effects, and less oily skin. She plans to provide updates and is not concerned about potential birth defects as she doesn't plan to have more children.

community Do I need to get professional advice?

in Advice 6 upvotes 5 years ago

A 22-year-old woman is experiencing genetic hair loss and has tried natural remedies like coconut oil and aloe vera without success. She seeks advice on whether to see a dermatologist or use treatments like Minoxidil (Rogaine) despite her parents' skepticism about professional help and chemical treatments.

community Hair growth and natural remedies? Are they worth of it ..

in Treatment 1 upvotes 2 months ago

The user discusses using Minoxidil and plans to start Finasteride for genetic hair loss. They also mention natural remedies like gold shilajit, moringa powder, a seed mixture, and cardio exercise, emphasizing that while these can help, Minoxidil and Finasteride are necessary.

community Hair loss and ethnicity - Caucasian men the most likely to experience hair loss

in Chat 17 upvotes 1 year ago

The conversation discusses how Caucasian men are more likely to experience hair loss due to genetic predisposition, with factors like the androgen receptor on the X chromosome playing a significant role. The user also expresses confusion about the evolutionary reasons for hair loss, especially in colder climates where it would seem beneficial to retain hair for warmth.

community Is there any way to know for sure if hair thinning is just from fungal infection/ inflammation and would be reversed with just Ketoconazole 2%/ triamcinolone acetonide etc?

2 upvotes 8 years ago

The user is unsure if their hair thinning is due to fungal infection/inflammation or genetic factors and is hesitant to start Minoxidil, finasteride, and RU58841. They are currently using Ketoconazole 2% and triamcinolone acetonide and are concerned about potential side effects from other medications.

community I want to sacrifice my hair in the name of science

in Chat 12 upvotes 1 year ago

The conversation discusses various theories of hair loss, including DHT sensitivity and genetic factors, with the user willing to use themselves for research due to having a hair loss gene but different hair loss patterns compared to their brothers. Specific treatments were not mentioned in the provided text.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 1 year ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

community Finasteride gives me seb derm. Thoughts on zinc or other options?

in Chat 15 upvotes 2 years ago

A user with diffuse hair loss after taking accutane, which might have triggered genetic predisposition to AGA; their experience taking finasteride and experiencing side effects of increased oil production, increased sex drive, worsening hair texture; they are considering zinc supplementation with finasteride or other treatments such as alfatradiol or spironolactone.

community Still not sure why men think diet has nothing to do with hair loss when scientific is quite the opposite [Link]

25 upvotes 6 years ago

Diet can influence hair health, but male pattern baldness (MPB) is primarily genetic. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Questions about a year of hairloss

in Treatment 1 upvotes 1 month ago

A 38-year-old man experiencing rapid hair loss plans to try minoxidil and a derma roller, and may consider finasteride if there's no improvement in six months. He seeks advice on genetic hair loss, baseline baldness, dandruff shampoo, and alternative treatments like tea tree oil and rosemary oil.

community Age 21 to 25, N3 to N2 in 4 years

in Progress Pictures 2 months ago

A user shared their hair regrowth journey from age 21 to 25 using finasteride and a carnivore diet. Other users debated the effectiveness of diet changes versus genetic factors in hair loss.

community Would starting dutastride and some other activities that probably raise testosterone increase the chance of side effects?

in General 66 upvotes 2 months ago

Combining finasteride and dutasteride with activities that raise testosterone may increase the risk of side effects like gynecomastia, depending on genetic predisposition and hormone levels. It's advised to check hormone levels to assess the risk.