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GlossaryGene Expression

process where genetic information directs protein or RNA synthesis

Gene expression is the process by which information from a gene is used to synthesize functional gene products, such as proteins or RNA. This process involves two main stages: transcription, where the DNA sequence of a gene is copied into mRNA, and translation, where the mRNA is used as a template to build proteins. Gene expression is tightly regulated to ensure that the right genes are expressed at the right times and in the right amounts, which is crucial for normal development, cellular function, and response to environmental changes.

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community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 10 months ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Why is it barely impossible to find balding South Korean men

in Research/Science 246 upvotes 1 year ago

The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.

community Just had this wild thought come into my head.

in Satire 403 upvotes 10 months ago

The conversation is about the debate over the existence of Post-Finasteride Syndrome (PFS) and its symptoms, with some users skeptical about PFS and others discussing side effects like erectile dysfunction and gynecomastia from hair loss treatments like finasteride. Specific treatments mentioned include finasteride, viagra, and a joke about using a popsicle stick for erectile support.

community My Testosterone results before and after Finasteride

in Update 146 upvotes 3 years ago

Finasteride significantly increased testosterone levels for the user, with no major side effects except watery semen, which was resolved with zinc supplements. The user's hairline stopped receding and slightly improved.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Testosterone and hair loss seeming irrelevance

in Research/Science 82 upvotes 1 year ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community The theory that explains everything - First Evidence of Hair regrow attributed to upregulating 3aHSD

in Treatment 174 upvotes 3 years ago

Hair regrowth treatment involving 3aHSD enzyme shows 6% improvement in 18 weeks. Sulforaphane, L-Menthol, and Dexpanthenol are potential ingredients for new hair loss solution.

community CB-03-01 supposed hair loss cure

in Treatment 9 upvotes 3 years ago

The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

community find a cure for this shit already

in Chat 209 upvotes 4 years ago

Treatments used to prevent and treat male pattern baldness, the difficulty in finding a permanent cure for hair loss, and the potential financial motivations of companies not wanting to find a cure.

community Being Safe on Oral Minoxidil: tl;dr on the literature.

in Research/Science 47 upvotes 1 week ago

Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

community [study analysis] Microdose of topical Finasteride for all the benefits and none of the sides?

in Research/Science 104 upvotes 4 years ago

Topical finasteride as a potential alternative to oral finasteride for reducing DHT levels on the scalp with fewer side effects, and other hair loss treatments such as minoxidil.

community Maintaining hair until Breezula without Fin

in Treatment 6 upvotes 4 years ago

A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.

community Is anyone taking creatine while on fin and/or dut?

in Finasteride/Dutasteride 33 upvotes 6 months ago

The conversation discusses the use of creatine while on finasteride and/or dutasteride for hair loss. Opinions vary, with some users reporting no issues and others experiencing accelerated hair loss, suggesting effects are individual.

community When you start balding you notice how unnatural this phenomenon is

in Chat 530 upvotes 2 weeks ago

Hair loss is a common issue, with treatments like finasteride and minoxidil used but not as permanent cures. Frustration exists over societal perceptions and the lack of a definitive solution.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 821 upvotes 5 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community We need to keep these snake oil companies accountable.

in Treatment 123 upvotes 6 months ago

Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 9 months ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community So does oral minoxidil age your skin or not

in Minoxidil 41 upvotes 9 months ago

Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.

community Stopped minoxidil for a year after a year of using it. Starting again.

in Minoxidil 158 upvotes 2 years ago

? This post by PastelDeUva discusses their experience with Minoxidil and Finasteride for hair loss treatments, which they stopped using for a year before resuming due to family's negative opinion. After restarting, they posted photos of the progression/regression of their hairline and are now planning on adding finasteride and dermarolling in order to get good results.

community Solving Hair Loss with Research at MIT

in Research/Science 595 upvotes 2 months ago

Hair loss treatments like minoxidil, finasteride, TDM-105795, and PP405. MIT is hosting a hackathon to find innovative hair loss solutions.

community Front page article at The New York Times (biggest circulation in the world) regarding notable results with oral minoxidil is a pretty big deal

in Minoxidil 2 years ago

This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.

community Dutasteride (.5mg) is some strong stuff!

in Finasteride/Dutasteride 58 upvotes 3 years ago

User switched from finasteride and minoxidil to dutasteride, experienced side effects, then took dutasteride once a week with improved hair density. Another user had success with daily dutasteride, while one had no results from topical dutasteride.

community Debunking the "Adverse metabolic consequences of dutasteride"

in Research/Science 40 upvotes 3 years ago

Dutasteride is more effective than finasteride, has neuroprotective benefits, and may prevent acne. Despite initial concerns about metabolic effects, further research suggests it is safe for most users, especially if not hypogonadal.

community Trying to understand finasteride side effects and post finasteride syndrome

in Finasteride/Dutasteride 73 upvotes 4 years ago

The conversation discusses the side effects of finasteride, including low libido and erectile dysfunction, and the possibility of these effects being permanent, known as post-finasteride syndrome (PFS). Some users report personal experiences with PFS and debate whether the condition is real, with varying opinions on the reversibility of side effects and the role of individual biology.

community 5 Months Hair Transplant Progress / 3500 Grafts

in Transplants 1663 upvotes 1 year ago

A user shared their positive experience with a hair transplant of 3500 grafts, showing significant improvement in appearance after 5 months. They underwent the procedure at Heva Clinic in Istanbul for $2,300 USD, which included aftercare, and attributed their hair loss to both genetics and traction alopecia from tight hairstyles.

community 5 months on oral min and fin. Im 23 years old.

in Progress Pictures 1283 upvotes 1 year ago

User experienced hair regrowth after 5 months on oral minoxidil and finasteride. Others praised the impressive results and mentioned the importance of combining treatments for best results.

community Anyone excited for CosmeRNA coming this month?

in Product 171 upvotes 1 year ago

CosmeRNA, a new hair loss treatment, is expected to release soon and may become part of the "big three" treatments alongside finasteride and minoxidil. It works differently from finasteride by targeting androgen receptors in hair follicles, potentially offering fewer side effects.

community 48 Days Fin, Min, and Derm Part 2

in Progress Pictures 264 upvotes 1 year ago

The user discussed their positive experience with hair loss treatments Finasteride, Minoxidil, and Dermarolling, showing significant progress in 48 days. Other users expressed interest in trying these treatments, asked about side effects, and one noted that they've observed good results in black people.

community Oral minoxidil is not good for your health, let’s use research chemicals bought from AliExpress

in Satire 551 upvotes 2 years ago

. This conversation discussed the efficacy of Minoxidil and Finasteride as treatments for hair loss, with a focus on the potential side effects of taking Oral Minoxidil. Some users shared their experiences with both treatments and there was debate over whether they were safe or not.