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GlossaryHair Follicle Epithelium

layer of cells lining the hair-producing cavity in skin

The hair follicle epithelium is the layer of cells that lines the hair follicle, which is the small cavity in the skin from which hair grows. This epithelium plays a crucial role in the growth, cycling, and regeneration of hair, and it includes various specialized cells that contribute to the formation and maintenance of the hair shaft.

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community The MPB itch aka DHT itch is very real.

SendMeKittyPorn in Chat 9 upvotes 1 year ago

Hair loss itch is caused by DHT attacking follicles and stimulating nerves. Finasteride users who respond well don't experience this itch.

community Sandalore: a scientific homemade approch

gioolio 20 upvotes 6 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community Long term finasteride users; Did you notice any improvement after 2 years?

SimmaG98 in Finasteride/Dutasteride 14 upvotes 1 year ago

Long term Finasteride users and whether or not they have noticed improvements after two years of use, with other treatments such as Minoxidil and dermarolling also discussed. Some replies suggest that improvement is possible even beyond the two year mark while others caution against believing studies backed by the Post-Finasteride Foundation.

Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

MagicBold in Research 823 upvotes 3 months ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 6 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Results of Procyanidin B2 in clinical studies

DSBarreto in Treatment 10 upvotes 4 years ago

Procyanidin B2, a compound derived from Annurca apples, as a potential treatment for pattern hair loss. Several clinical studies were mentioned, which found that procyanidin B2 could increase hair growth, density, and keratin content. Other treatments such as Minoxidil, Finasteride, and RU58841 were not discussed.

community Comprehensive Microneedling Guide

throwoveraccount in Microneedling 294 upvotes 2 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community SAFFLOWER OIL good alternative for Minoxidil?

Kaiox9000 in Treatment 1 upvotes 5 years ago

Safflower oil is suggested as an alternative to minoxidil for hair growth, with benefits including scalp conditioning and hair strength enhancement. Studies indicate it may also reverse scalp dermatitis, alopecia, and prevent premature grayness.

community Finasteride only reduces scalp DHT by ~40%. Why does it work?

andreas_jacob in Finasteride/Dutasteride 37 upvotes 1 year ago

How Finasteride and Dutasteride help reduce hair loss by reducing the amount of DHT in scalp areas, as well as discussing factors such as sensitivity to DHT, 5α-reductase expression in different parts of the hair follicle, and scalp tension.

community TWIST-1 and the cure: Is it really that easy?

ProposalInside7538 in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

DSBarreto in Research/Science 479 upvotes 6 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community HairClone developing cell replacement treatments for Hair Loss

HairClone 6 upvotes 6 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community Why is Minoxidil not enough for hair loss? (No fin)

ghristov in Minoxidil 55 upvotes 1 month ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.

community Unofficial Dermapen/Roller Guide

X211499Reddit in Treatment 251 upvotes 6 years ago

Treatments for hair loss, including microneedling (dermarolling and dermapen) and the use of minoxidil, finasteride, and RU58841. It provides detailed information about cost and usage of the various treatments, as well as potential side effects.

community Is it possible for androgenic alopecia to begin at early adolescent years?

Uncle__Sheogorath in Chat 70 upvotes 1 year ago

Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.

community UPDATE: The theory that explains everything. Please help me make this big!

joaopassos4444 in Research/Science 448 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community Microneedling and aloe vera to recruit stem cells.

capilluscare in Chat 11 upvotes 1 year ago

Microneedling combined with aloe vera may stimulate dormant stem cells in hair loss areas. Minoxidil is also suggested for better results.

community This is the best time in human history to be fighting hair loss

ToughEast838 in Treatment 194 upvotes 2 years ago

This conversation discusses the advancements in treatments for hair loss, including finasteride, dutasteride, minoxidil and new promising treatments such as pyrilutamide and verteporfin. Other treatments discussed were taking minoxidil orally, tretinoin to turn non-responders into responders and microneedling to further boost growth.

community I just made 60x of 5mg minoxidil sugar cubes

lohikuningas in Minoxidil 1321 upvotes 2 months ago

A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

diego8895 in Research/Science 14 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community Dr Huberman - Cafeine when rubbed on the scalp can be as effective at times as minoxidil because it triggers 1GF-1

eddsters in Update 268 upvotes 1 year ago

Whether topical caffeine can be as effective for hair growth as minoxidil and finasteride, with various replies discussing the efficacy of these treatments and criticism of Dr. Huberman's research methods.

community Fevipiprant 2019!

Folliman 17 upvotes 8 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

community A meta analysis of 18 popular hair loss treatments. An 2022 guide on efficacy. From finasteride and minoxidil to caffeine shampoo, saw palmetto and biotin. 96 Scientific References included.

MENSCRIPT in Research/Science 101 upvotes 2 years ago

Most hair loss treatments are ineffective; only finasteride, dutasteride, and minoxidil show effectiveness.

community KX-826 Phase 3 Failed. Sorry guys...

_The_Quiet_Place_ in Research/Science 51 upvotes 1 year ago

The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

community Sup lads. Needing some Pyrilutamide updates.

shegotaloosepussay in Research/Science 17 upvotes 2 years ago

Hair loss treatments, specifically Pyrilutamide and Minoxidil/Finasteride/RU58841. Participants discussed their experiences with them and the results they have seen so far.

community Why some of my hairs are looking like this?

racerz634 in Update 142 upvotes 1 year ago

User 3 months post hair transplant, using minoxidil and dutasteride. Users discuss possible reasons for odd-looking hair strands.

community Should I stop or is this normal?

MaleficentIsopod5670 in Treatment 5 upvotes 6 months ago

Increased hair fall after starting minoxidil, dutasteride, and biotin is normal. Hair may grow faster, and shaving your head is fine while on these medications.

community Alright boys, who’s willing to burn their scalp for science?

peterstiglitz in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community Theory And Observation: Why Being Bald Can Really Work

justaskinthequestion in Shaved/buzzed 88 upvotes 11 months ago

The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.

community Shedding a lot (including smaller hairs) while on topical min and dut

notWierdAtAll in Treatment 12 upvotes 6 months ago

The user has been using topical minoxidil and dutasteride but is experiencing significant hair shedding, including smaller hairs. They are concerned if this shedding indicates the treatment is working.