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GlossaryLipolysis (fat catabolism)

biological process breaking down fats into glycerol and fatty acids

Lipolysis is the biological process where fats (lipids) stored in fat cells (adipocytes) are broken down into glycerol and free fatty acids. This process is crucial for providing energy to the body, especially during periods of fasting or intense exercise, and is regulated by hormones such as adrenaline, noradrenaline, and insulin.

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community How to know if shedding is from tren or minoxidil?

in Minoxidil 5 upvotes 7 months ago

The user started using trenbolone and minoxidil simultaneously and experienced increased hair shedding, unsure which is causing it. Replies suggest both drugs could cause hair loss, with one advising to stop trenbolone to protect hair and another indicating minoxidil is unlikely the cause due to the timing.

community The Big Fat Layer / Remedies: Cetirizine

in Treatment 12 upvotes 3 years ago

Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.

community The Big Fat Layer II

in Research/Science 26 upvotes 3 years ago

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

community Injecting stomach fat into the scalp could cure baldness in just six months

in Update 114 upvotes 6 years ago

A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

community When I was in my 20s, skinny and with long hair, one of my biggest fear was being fat and bald in my 40s. Now that it’s come to pass, I’ve found there are better things to worry about. I started shaving my head in 05 when I was 32 and I can sum it all up in one word: Liberating.

in Shaved/buzzed 478 upvotes 3 years ago

Accepting hair loss, with solutions discussed including Minoxidil and Finasteride treatments, shaving the head as a liberating experience, and using beards to make up for lack of hair.

community Anyone experienced weight gain on dutasteride?

in Finasteride/Dutasteride 6 upvotes 2 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community 11 months of 1.5 mg Finasteride with blood samples

in Finasteride/Dutasteride 290 upvotes 5 months ago

A user took 1.5 mg Finasteride and topical Minoxidil for 11 months, resulting in significant changes in blood values but no noticeable hair improvement. They experienced side effects like mood swings and increased visceral fat, leading them to stop Finasteride.

community New Treatments, and a Huge Group Buy with Lots of Research

in Research/Science 109 upvotes 1 year ago

A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

community minoxidil on eyebrows feedback

in Female 4 upvotes 1 year ago

A female user is seeking feedback on using topical minoxidil on eyebrows due to eyebrow loss, as oral minoxidil hasn't worked and they avoid Latisse due to potential fat loss.

community Why I really believe the tension theory is the cause of MPB

in Research/Science 70 upvotes 3 years ago

The conversation discusses the tension theory as a cause of male pattern baldness (MPB), suggesting that scalp tension and reduced subcutaneous fat layer contribute to hair loss. Treatments mentioned include Minoxidil, finasteride, microneedling, scalp massages, and Botox.

community My experience with dutasteride 4.5 months and oral minoxidil 1.5 months so far

in Finasteride/Dutasteride 10 upvotes 3 years ago

The user switched from finasteride to dutasteride and added oral minoxidil, which helped regrow their hairline and reduce shedding. They experienced side effects like brain fog, sluggishness, and fat gain with dutasteride, and slight chest tightness with oral minoxidil.

community How I treated side effects

6 upvotes 5 years ago

The conversation discusses treating side effects of hair loss treatments. Recommendations include lifting heavy weights, reducing body fat, taking ZMA and D3 supplements, improving diet, taking DIM, reducing finasteride dosage, avoiding alcohol, drinking water, getting quality sleep, and not obsessing over side effects.

community Supplements for hair growth (Alcoholics, Smokers; and Gym Goers)

in Treatment 6 upvotes 4 months ago

A user shared their experience with hair loss and recommended supplements like magnesium, vitamin D, vitamin C, zinc, iron, and protein, along with using a dermaroller. They noted benefits such as accelerated fat loss, muscle growth, better digestion, increased testosterone, and improved hair and skin quality.

community My experience on the Peat diet

6 upvotes 10 years ago

Following a Ray Peat diet led to less hair fall, thicker hair, and new hair growth at bald spots. The diet included stopping Omega 3 supplements, eating liver, increasing fruit, sugar, and saturated fat intake, and occasionally consuming coffee, tea, raw carrots, and shellfish.

community THE BEST SERENOA REPENS (saw palmetto) SUPPLEMENT

in Product 11 months ago

The conversation is about finding the best quality and price for a saw palmetto supplement for hair loss. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

community Did pre-tests before starting finasteride, turns out I have abnormally high estrogen

in Finasteride/Dutasteride 1 upvotes 3 months ago

A 23-year-old with high estrogen levels is considering starting finasteride for hair loss and plans to use a low dose topical treatment while also seeking to lower estrogen levels. They will consult an endocrinologist for further guidance.

community Feeling good about one year's progress. Daily oral fin/topical min, no side effects.

in Progress Pictures 972 upvotes 8 months ago

A user shared their one-year hair regrowth progress using daily oral finasteride and topical minoxidil without side effects. Some people are impressed, asking for more details, while others suggest a hair transplant for further improvement.

community What to do about High E2 levels on Finasteride?

in Treatment 6 upvotes 2 years ago

User experienced high E2 levels after taking finasteride and sought advice on lowering E2 with supplements like Tonkat ali, Fadogia, and Boron. They also used DIM, zinc, and magnesium but avoided using an AI.

community Using Antihypertensive drugs for hair loss

in Chat 6 upvotes 2 years ago

The conversation discusses the potential connection between baldness, heart disease, and high blood pressure. Treatments mentioned include Minoxidil, Spironolactone, and Finasteride.

community Actor Jacob Batalon, 26, has a receding hairline. I thought it was pretty cool to see a younger actor being successful, despite dealing with hair loss. His most well known role is Ned Leeds in the Marvel Cinematic Universe, and he is currently the CEO of Sex.

in Satire 498 upvotes 1 year ago

Actor Jacob Batalon's receding hairline and how it is a sign of his success despite dealing with hair loss, with some people suggesting he may be using treatments such as Minoxidil or Finasteride to manage it.

community please give me some advice. I don't know what to do next.. do I give up?

in Treatment 8 upvotes 2 years ago

A user is experiencing anxiety and insecurity about hair loss despite using finasteride for 19 months and oral minoxidil for 6 months. They are seeking advice on whether stress, scalp testosterone, or switching treatments could help, and are considering a buzzcut.

community Not sure what else to do, can’t use anti-androgens (Baseline Hormonal Bloodwork included) need advice badly

in Update 6 upvotes 3 years ago

User experienced feminizing side effects from finasteride and tried RU, alfatradiol, and finasteride without success. They are now considering treatments like Stemoxydine, Zix, Minoxidil, Dermarolling, Eucapil, and a hair transplant.

community Are any of these DHT inhibitors (RENU Biogen)

in Product 1 upvotes 5 months ago

The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. The user inquires if RENU Biogen is a DHT inhibitor.

community 5 months of 1mg Fin, weekly 1.5mm microneedling and daily 2mg copper peptide injections

in Progress Pictures 77 upvotes 5 months ago

The user shared progress pictures after 5 months of using 1mg finasteride, weekly 1.5mm microneedling, and daily 2mg copper peptide injections. They discussed their hair loss treatment and results.

community Besides Vitamin D, what other blood tests would you recommend getting if insurance will cover it?

in Treatment 4 upvotes 11 months ago

The conversation is about which blood tests to get for hair loss treatment, besides Vitamin D. No specific treatments were mentioned.

community Nine Month Progress: Bless The Person Who Developed Finasteride And Minoxidil (20M)

in Progress Pictures 587 upvotes 11 months ago

A user shared a nine-month hair regrowth progress using 5mg oral Minoxidil and 1.25mg oral Finasteride daily, with noticeable improvement and no side effects, despite a high-protein diet, occasional smoking, and regular exercise. They also mentioned using keto shampoo and having naturally increased body hair by about 10%.

community Minoxidil + Gym + Cutting. Is it bad?

in Minoxidil 38 upvotes 1 year ago

A user is concerned about weight loss stagnation while using minoxidil and finasteride during a calorie-cutting diet. Responses suggest water retention or a weight loss plateau as possible causes.

community Coconut oil and hair maintenance

in Chat 6 upvotes 2 years ago

A 28-year-old male on TRT with a family history of MPB reports that consuming 1-2 tbsp of virgin coconut oil daily reduces hair loss and improves hair condition. Stopping the oil leads to increased hair fall and dryness.

community Dutasteride 0.5 mg 9 months update- Super happy with results

in Finasteride/Dutasteride 2 years ago

A user's update on their 9 month use of Dutasteride 0.5 mg as a treatment for hair loss, with other users giving feedback and advice.