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GlossaryEx Vivo Permeation

study of substance movement through tissues outside organisms

Ex Vivo Permeation refers to the study of how substances, such as drugs or chemicals, pass through biological tissues outside of a living organism. For example, researchers might use skin samples from a donor to test how well a new topical medication can penetrate the skin layers. This method helps in understanding the effectiveness and safety of products before they are tested in living subjects.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 5 months ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Study published yesterday : "Brassica oleracea extract, glucosinlates and sulforaphane promote hair growth in vitro and Ex vivo"

in Research/Science 36 upvotes 3 years ago

The conversation discusses hair loss treatments, specifically Brassica oleracea extract, glucosinolates, and sulforaphane, and their potential to promote hair growth. Users also mention minoxidil and finasteride as existing treatments.

community Red Ginseng Extract Promotes the Hair Growth in Cultured Human Hair Follicles

17 upvotes 6 years ago

The conversation is about hair loss treatments, specifically discussing the effectiveness of Red Ginseng Extract in promoting hair growth. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

community to all people who cannot tolerate anti androgens (loe dose topical fin, pyrilutamide, CB) i am getting desperate, looking for a solution

in Research/Science 13 upvotes 1 year ago

The user tried Minoxidil without success, and Finasteride worked but caused sexual side effects even at a very low dose. They are seeking alternative treatments for hair loss as they cannot tolerate anti-androgens and are also in therapy for mental health.

community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

in Research/Science 198 upvotes 2 days ago

PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 2 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community 0.5mg Dutasteride promotes more “regrowth” than 5mg oral Minoxidil

in Research/Science 117 upvotes 10 months ago

Dutasteride promotes more hair regrowth than Minoxidil. Users discuss combining treatments for better results and share personal experiences with side effects.

community U/joaopassos444 , HATS OFF brother !!

in Research/Science 123 upvotes 3 years ago

A new hair loss treatment theory beyond minoxidil and finasteride is proposed, causing mixed reactions in the community, with some members eager to explore and support it, while others call for more research and evidence.

community Listen to anyone besides your Mom while fighting hair-loss

in Satire 464 upvotes 4 years ago

Hair loss treatments, with people sharing their experiences of trying to get help from family members and how genetics can affect the severity of hair loss. Treatments mentioned include finasteride, minoxidil, RU58841, scalp massage, whey protein and bleaching.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 41 upvotes 5 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community Oxytocin Pathway and Cinnamic Acid Research

in Research/Science 15 upvotes 8 months ago

The conversation discusses the potential of cinnamic acid for hair growth. It also mentions treatments like Minoxidil, finasteride, and RU58841.

community 5 months progress on fin and min

in Progress Pictures 1796 upvotes 1 month ago

Significant hair regrowth was achieved using oral finasteride and topical minoxidil over five months, with noticeable improvements in hairline and temple areas. The user experienced minimal side effects, mainly increased eyebrow and eyelash growth, and attributes additional physical improvements to weight loss and exercise.

community Hair Loss Due To Chlorine and Hard Metals In Water?

in Research/Science 1 upvotes 2 months ago

Hair loss possibly caused by chlorine and heavy metals in water was addressed by using a shower filter, ketoconazole shampoo, and PRP sessions, which stopped the hair loss but did not lead to regrowth. Other users suggested similar experiences and solutions, emphasizing the importance of a good water filter and patience for potential regrowth.

community blueprint is working so well it seems

in Chat 538 upvotes 4 months ago

The conversation discusses a person successfully using a combination of Minoxidil, finasteride, and other treatments for hair loss, resulting in significantly improved hair. Despite some criticism, many admire his dedication to health and anti-aging research.

community Finasteride and minoxidil seem to do wonders, two months update

in Progress Pictures 282 upvotes 4 months ago

Finasteride and minoxidil show significant hair growth in two months. User might skip hair transplant if progress continues.

community Refused to take pictures at my friends wedding because i’m balding

in Chat 255 upvotes 5 months ago

A user expressed deep frustration and embarrassment about balding, especially at a friend's wedding, and mentioned using finasteride and minoxidil. Others shared similar experiences and offered support, with some suggesting therapy and hair treatments.

community 4 years, 1mg fin daily (was on and off at first), minoxidil for first 3 years then stopped

in Progress Pictures 217 upvotes 6 months ago

User used finasteride and minoxidil for hair loss, experienced side effects initially, but saw improvement after stopping minoxidil and ignoring side effects. New hairstyle also improved hair appearance.

community 4 month result, can I make it ? NW 6 to NW 2😂

in Progress Pictures 20 upvotes 6 months ago

A user shared progress pictures showing improvement from NW 6 to NW 2 after four months of treatment. They are considering using exosomes to further reverse hair miniaturization.

community bye fellas, it’s time to quit this sub

in Progress Pictures 810 upvotes 8 months ago

A user successfully improved their hairline after 15 months using topical minoxidil and dutasteride. Some commenters question the necessity of treatment given the user's original hair condition, while others support early intervention.

community Fluridil downregulates androgen receptor expression?

in Research/Science 1 upvotes 11 months ago

Fluridil may decrease the number of androgen receptors in hair follicles by up to 95%. This suggests a different action mechanism from other non-steroidal antiandrogens like RU58841, indicating they might be used together.

community 5 month Min/Fin Update! Progress pics below 🤩

in Progress Pictures 512 upvotes 1 year ago

The post and conversation are about a user's positive progress with hair loss using minoxidil and finasteride. No noticeable side effects were reported.

community Doctor prescribed me 1mg oral Fin and 1.25mg oral minox, is this a good start?

in Treatment 13 upvotes 1 year ago

User discussed oral Fin (1mg) and oral Minox (1.25mg) for hair growth with doctor. Others approve of the treatment plan.

community I don’t even care about my hair I just like taking drugs

in Satire 1 year ago

A user's experimentation with various hair loss treatments, including medications and topical applications; as well as their desire to experience unusual sensations through the use of drugs.

community Propecia/Finasteride Where does it come from?

in Finasteride/Dutasteride 3 upvotes 2 years ago

The user is taking finasteride 1mg from Blink pharmacy, sourced from Ascend Laboratories, with no noticeable side effects after 5 months. They also use Kirkland foam minoxidil, micro needling, and various supplements for hair treatment.

community Why it always be young guys with hair like this ask if they going bald?

in Satire 523 upvotes 2 years ago

Young guys with thick hair asking if they're going bald and people discussing early action for hair loss treatments like Minoxidil and Finasteride. Some users share their positive experiences with these treatments.

community The following ingredients dramatically reduced hairfall for me after 3 months

in Chat 35 upvotes 3 years ago

The original poster found that using rosemary oil, peppermint oil, jojoba oil, oral castor oil, head massages, ketoconazole shampoo, omega-3 fatty acids, and a multivitamin reduced their hair loss from 150 to 50 hairs a day. Another person reported a significant drop in hair loss using a similar oil blend with additional ingredients.

community MPB since 16. 31 now, recovering from PFS, and getting back in the game.

in Treatment 6 upvotes 4 years ago

User experienced hair loss since 16, used Fin, Minox, and Nizoral with success but stopped due to side effects. Now using Pur D'or shampoo, Rogaine foam, scalp massages, volumizing spray, and dermarolling for hair maintenance.

community I honestly think Dutasteride at 2.5mg could be the ultimate cure for hair loss.

in Chat 213 upvotes 3 weeks ago

Dutasteride at 2.5mg is considered a potential hair loss cure due to its DHT-blocking ability, but there are concerns about side effects and individual responses. Minoxidil, finasteride, and RU58841 are also discussed, with mixed opinions on their effectiveness and safety.