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    Did you mean Endothelial Dysfunction?
    Glossary Endothelial Dysfunction

    inner lining of blood vessels fails to regulate functions properly

    Endothelial dysfunction refers to a condition where the inner lining of blood vessels, known as the endothelium, does not function properly. This can lead to various cardiovascular problems because the endothelium plays a crucial role in regulating blood flow, blood clotting, and immune function. When it is impaired, it can contribute to the development of atherosclerosis, hypertension, and other vascular diseases.

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      community 2026 Hairloss Nuclear Stack Update

       83 upvotes 6 months ago
      A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.

      community A Theory on Why Microneedling Works

       175 upvotes 6 years ago
      Microneedling may enhance hair regrowth by transferring stem cells to dormant follicles, improving the effects of minoxidil. Users discuss using microneedling with needle lengths around 1.5mm to stimulate hair growth.

      community Those minoxidil collagen studies

       3 upvotes 1 year ago
      Minoxidil stimulates hair growth by affecting hair follicle cycles and may inhibit collagen synthesis under certain conditions. The user also mentions using vitamin D and red light therapy as part of their hair loss treatment.

      community Short Peptides for Hair Loss: anyone tried any of these?

       14 upvotes 5 months ago
      Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.

      community Comprehensive Microneedling Guide

       292 upvotes 4 years ago
      Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

      community Being Safe on Oral Minoxidil: tl;dr on the literature.

       51 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community BPC-157 and Angiogenesis. Bro-Science-Execution-Plan

      in Research/Science  13 upvotes 1 year ago
      BPC-157 may promote hair growth by increasing angiogenesis, similar to how Minoxidil works, though no direct research confirms this yet. Users report combining BPC-157 with Minoxidil and finasteride for better results, but concerns about long-term safety exist.

      community Someone please offer reassurance

      in Minoxidil  3 upvotes 1 month ago
      A 19-year-old male is experiencing hair shedding while using oral minoxidil, ketoconazole, dermastamping, and saw palmetto, and is considering switching to finasteride for better results. Users suggest that saw palmetto may not be effective and recommend finasteride instead, while also discussing other treatments like rosemary oil, peppermint oil, and pumpkin seed oil.

      community NMN supplementation experiences?

       2 upvotes 8 months ago
      The conversation discusses experiences with NMN supplementation for hair growth, with some users reporting increased hair growth activity and others seeing no significant changes. OP has been using dutasteride and oral minoxidil, and recently added NMN, noticing increased shedding, which they hope indicates new hair growth.

      community Natural, topical solutions for hair loss

      9 months ago
      Natural topical solutions for hair loss, such as saw palmetto and essential oils, are generally less effective than treatments like finasteride and minoxidil. While some users report minor benefits from natural products, most agree that they are not potent enough to combat significant hair loss.

      community Anyone using oral castor oil in their stack?

       4 upvotes 2 years ago
      The conversation discusses using oral castor oil as a hair growth stimulant for beard and scalp hair. One user questions its use, noting castor oil is typically a laxative in the Philippines.

      community Brotzu lotion update

       87 upvotes 8 years ago
      A new hair loss lotion by Dr. Brotzu, expected to regrow up to 5 years of lost hair, is set to be released by Fidia Farmaceutici. It claims to work like minoxidil and finasteride without side effects, but skepticism exists due to its classification as a cosmetic product.

      community My blood work as a person with Ed suffer

       5 upvotes 4 years ago
      High estradiol levels may contribute to erectile dysfunction (ED) and can be addressed with lifestyle changes or medication. It's important to consult a medical professional for treatment options.

      community Green tea/ soy Isoflavones supplements for MPB

       4 upvotes 5 years ago
      Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.

      community Why Hair Loss Needs Proper Diagnosis (Dermatologist Insight)

      in Treatment  66 upvotes 7 months ago
      Hair loss requires proper diagnosis as it can have various causes, and treatments like finasteride, minoxidil, and dutasteride are often used. Many people express frustration with dermatologists and turn to self-research and alternative sources for treatment.

      community Dutas and Minox results - mixed feelings

       240 upvotes 10 months ago
      A user experienced significant hair growth using oral dutasteride and minoxidil but developed severe erectile dysfunction, likely exacerbated by obesity and diabetes. They plan to lose weight and possibly adjust medication to alleviate side effects.

      community only microneedling and supplements

      in Progress Pictures  71 upvotes 1 year ago
      The user used microneedling, zinc, vitamin D3, biotin, magnesium, saw palmetto, pumpkin seed oil, and a DHT-blocker shampoo with biotin for hair loss. They are considering adding minoxidil due to stagnation in progress.

      community Do you keep gains if you stop microneedling?

      in Microneedling  15 upvotes 1 year ago
      Stopping microneedling may result in losing hair gains, as it enhances the effectiveness of treatments like minoxidil. Combining microneedling with minoxidil and finasteride is more effective than using microneedling alone.