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GlossaryDouble-stranded RNA

molecule with two complementary RNA strands bound together

Double-stranded RNA (dsRNA) is a molecule consisting of two complementary strands of RNA that are bound together, similar to the structure of DNA. In biological systems, dsRNA is often a signal of viral infection, triggering immune responses in cells. It is also used in research and therapeutic applications, such as RNA interference (RNAi), to silence specific genes.

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community Double jaw surgery induced intense shed, pyrilutamide stopped it in its tracks

in Treatment 1 upvotes 1 year ago

After jaw surgery caused intense hair shedding and scalp itch, using pyrilutamide significantly reduced these symptoms. It's suggested to test pyrilutamide for authenticity before use, despite positive personal experience with the product from MV Supplements.

community Effect of Pumpkin Seed Oil on Hair Growth in Men with Androgenetic Alopecia: A Randomized, Double-Blind, Placebo-Controlled Trial

23 upvotes 7 years ago

Pumpkin seed oil may help hair growth in men with androgenetic alopecia. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Why haven’t we seen anything about this

in Research/Science 18 upvotes 4 years ago

A double blind, placebo-controlled study that looked into the potential effectiveness of topical fluridil for treating male androgenetic alopecia, showing increased anagen to telogen ratios with no reported side effects on libido or sexual performance.

community 35% regrowth brothers and sisters! More effective than Minox and Fin?

in Treatment 107 upvotes 6 years ago

A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

community Can someone explain the Dutasteride hysteria in this community?

in Finasteride/Dutasteride 58 upvotes 1 year ago

The conversation is about the double standard in the hair loss community regarding shedding when using different treatments. The conclusion is that shedding is considered normal when starting finasteride or minoxidil, but not when starting dutasteride, despite the fact that dutasteride is more effective at reducing DHT.

community Helicobacter's concocted serum v1

7 upvotes 5 years ago

A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

community Rate my regimen - Is it fine to do everything at once as long as the min is dry?

in Treatment 7 upvotes 1 year ago

The user is using a hair loss treatment regimen that includes double the recommended dose of Minoxidil foam once nightly, a mix of RU58841 and stemoxydine after the Minoxidil dries, ketoconazole every other day, and weekly microneedling with alternating depths. They are also considering starting finasteride soon.

community I felt it when he said it is devastating to lose your hair as a man. Spoken like someone who has felt the horror of male parent blandness.

in Satire 400 upvotes 1 year ago

The devastating effects of male pattern baldness and how it can be seen as a societal double standard, with many people mocking those who experience hair loss. People shared their own experiences of hair loss and discussed potential treatments such as hair transplants, Minoxidil, finasteride, and RU58841.

community September 2023 vs December 2024

in Progress Pictures 55 upvotes 1 week ago

The user switched from finasteride and topical minoxidil to dutasteride and oral minoxidil due to side effects but is experiencing further hair recession. They plan to double the dosage, despite mixed feedback on the effectiveness and potential side effects of the treatments.

community Can I punch someone if they make fun of my hair loss, just like Will Smith did?

in Chat 448 upvotes 2 years ago

Hair loss's social impact, focusing on Will Smith defending Jada Pinkett Smith's alopecia. The conversation highlights double standards between men and women experiencing hair loss and emphasizes empathy.

community Progress update: 7 months since starting treatment hair is a bit longer now. Happy with results so far. fin / min

in Progress Pictures 431 upvotes 3 years ago

Person shared 7-month progress of hair growth using finasteride, minoxidil, and nizoral shampoo. Happy with results, experienced minimal shedding, and applies double dose of minoxidil at night.

community The problem with hair fibers 🤣

in Satire 45 upvotes 3 years ago

Hair loss discussion includes treatments like Minoxidil, Finasteride, and RU58841. Conversation highlights double standards with hair fibers and women's wigs/makeup/extensions/eyelashes.

community Considering giving a laser comb a shot. Here’s a summary of my research on the subject.

8 upvotes 8 years ago

Considering adding Low Level Laser Therapy (LLLT) to a hair loss prevention regimen; discussing the effectiveness of LLLT, and evaluating double-blind random-controlled trials that have been conducted on laser combs.

community Why do people feel the need to comment on my hair when they know there's nothing I can do about it?

in Chat 72 upvotes 8 months ago

A 28-year-old started using finasteride and minoxidil for hair loss and is frustrated by insensitive comments from others about his balding, which is a sensitive topic for him. People, including a girl he's seeing, have made hurtful remarks, and the conversation includes discussions on societal double standards and advice to ignore such comments and focus on self-improvement.

community An Interesting Study With a Decent Sample Size Finding Caffeine Liquid to Have Similar Effectiveness to Minoxidil

in Minoxidil 7 upvotes 5 years ago

Caffeine liquid may be as effective as Minoxidil for hair loss and could be used together for added benefits. However, the credibility of the research is questionable due to potential bias, as the study was sponsored by a company that sells caffeine solution and was not double-blind.

community To whomever started using Pyri/Koshine, Please TELL US!

in Chat 14 upvotes 4 months ago

The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Users are asked to share their experiences with Pyri/Koshine.

community Good Progress Results 7 Months 1mg Finasteride 2.5mg minoxil [22M]

in Progress Pictures 142 upvotes 6 months ago

A user shared progress pictures showing significant hair growth after 7 months of using 1mg finasteride and 2.5mg minoxidil. The user also noted improved beard growth.

community This true? Sult1a1 enzyme booster 2025

in Technology 8 upvotes 1 week ago

The conversation discusses the potential effectiveness of a Sult1a1 enzyme booster in enhancing the results of minoxidil for hair loss. Users express interest in the booster, hoping it will improve the effectiveness of oral minoxidil, especially for those who struggle with topical application.

community 21m one month result fin,min,keto

in Progress Pictures 10 upvotes 2 months ago

A 21-year-old male used ketoconazole shampoo, 1mg finasteride, 5% topical minoxidil, and 5mg oral minoxidil for hair loss, with no side effects reported. He applied topical minoxidil only to thinning areas to promote hair and beard growth.

community Been using Dutasteride, Ru58841, Minoxidil, and Ketaconozole for years. Still can't stop shed, recession or loss of density.

in Treatment 1 upvotes 2 months ago

Despite using dutasteride, RU58841, minoxidil, and ketoconazole for years, the user continues to experience severe hair loss and thinning. They seek advice after multiple dermatologists confirmed androgenetic alopecia (AGA) but offered no effective solutions.

community Is this the best current Stack that doesnt involve FIN/DUT?

in Treatment 7 upvotes 3 months ago

The post and conversation are about a hair loss treatment stack without finasteride or dutasteride. The suggested treatments include Alfatradiol, Koshine826, Ketoconazole lotion, Minoxidil, microneedling, Tretinoin, and Stemoxydine.

community Saw Palmetto/Pumkin seed gives basically same results as Fin

in Treatment 4 months ago

A user reported that Procerin, containing Saw Palmetto and Pumpkin seed oil, provided similar hair thickening results as finasteride but with milder side effects. They experienced reduced libido and watery ejaculations but are adjusting the dose to minimize these effects.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 60 upvotes 5 months ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

community My hair after 3 steroid cycles

in Progress Pictures 27 upvotes 5 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community After 3 months of 5% topical minoxidil

in Progress Pictures 198 upvotes 1 year ago

After 3 months of using 5% topical minoxidil once a day and additional natural oils, a user reports good hair regrowth and is considering adding topical finasteride. They also use 0.5mm microneedling once a week.

community One year of dudasteride and minoxidil daily

in Progress Pictures 1 year ago

This conversation details the impressive one year progress of a user's hair loss treatment, which included taking daily doses of dutasteride and minoxidil. Other users shared their own experiences with similar treatments, such as not having any shedding when starting, or having an oily scalp that improved significantly.

community Pyrilutamide Results, Safety and WHERE You can BUY IT!

in Research/Science 9 upvotes 2 years ago

The conversation discusses skepticism over the results of Pyrilutamide for hair regrowth, suggesting that results from rigorous trials are more trustworthy. Specific treatments mentioned include Minoxidil, finasteride, and RU58841.

community fin/min + dermaroller, 3 months progress. Starting to see some improvements

in Progress Pictures 2 years ago

A user's 3-month progress with a combination of finasteride, minoxidil and dermarolling for hair loss; other users shared their experiences and advice.

community Any recs for a shampoo with 1% Keto and Sulfate free?

in Ketoconazole 1 upvotes 3 years ago

A user is seeking recommendations for a shampoo with 1% Ketoconazole that is sulfate-free. They are looking for a product without 'sodium laureth sulfate.'

community Tip for anyone who is worried about minoxidil messing up their skin

in Minoxidil 39 upvotes 3 years ago

Use retin-a cream and maintain a good skincare routine to counteract skin issues caused by topical minoxidil. Taking sublingual minoxidil can also be beneficial.