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      community Being Safe on Oral Minoxidil: tl;dr on the literature.

       51 upvotes 1 year ago
      Oral minoxidil is effective for hair loss but can cause cardiovascular side effects, such as pericardial effusion, especially in those with genetic predispositions. Starting with low doses and monitoring cardiovascular health are advised to reduce risks.

      community The Real Cause Of Androgenetic Alopecia

       675 upvotes 1 year ago
      Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

      community DHT is about to get smashed ….

       802 upvotes 2 years ago
      The conversation discusses hair loss treatments like topical finasteride with minoxidil, oral dutasteride, and essential oils. Oral treatments like dutasteride and finasteride are seen as more effective, though some prefer topicals to avoid side effects.

      community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

      in Research/Science  64 upvotes 2 years ago
      The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community What if DHT is not the vilan.

       13 upvotes 5 years ago
      Hair loss may be influenced more by inflammation, microbiome imbalances, and gut health than DHT. Treatments discussed include minoxidil, finasteride, RU58841, fecal microbiota transplants, and JAK inhibitors.

      community Is this true? It can be a major breakthrough

       1008 upvotes 4 months ago
      Deoxyribose sugar gel may stimulate hair regrowth similarly to minoxidil by enhancing blood supply and follicle activity. Human trials are necessary, and current products have mixed results.

      community Oral minoxidil — is it actually worth it?

      in Minoxidil  42 upvotes 8 months ago
      Oral minoxidil is effective for hair loss but may cause side effects like increased heart rate and edema. Finasteride is recommended, with dutasteride as an alternative if needed.

      community I had claude create a protocol only using fda approved drugs.

       4 upvotes 8 months ago
      A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      5 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 8 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community Transition protocols from fin to dut

      in Chat  2 upvotes 6 months ago
      Transitioning from finasteride to dutasteride for hair loss, with suggestions to either slowly transition or frontload dutasteride. The user is also using minoxidil, nizoral, needling, and LLLT.

      community Regimen proposal (incl. dut meso) (event industry)

       1 upvotes 1 year ago
      A user in their early 20s is concerned about minor hair thinning and is considering a hair loss regimen involving PRP sessions, mesotherapy with dutasteride injections, and low-dose finasteride. They dislike minoxidil due to its greasiness and prefer a routine that is easy to maintain.

      community Trialing the probiotics BB536, PTA 6475 so you don’t have to

       75 upvotes 1 year ago
      Probiotics like L. reuteri ATCC PTA 6475 and B. longum BB536 may improve hair growth and density by reducing inflammation and reversing DHT damage. The user is trialing these probiotics personally, ordering them from the U.S. to Canada, and plans to continue if no adverse effects occur.

      community What is the deal with "longitudinal partial follicular unit transplantation"

       3 upvotes 6 years ago
      Longitudinal partial follicular unit transplantation involves extracting part of the donor follicular unit, allowing the donor area to maintain hair production and potentially increasing transplant yield. The conversation questions if this method is practiced in clinics or remains theoretical, and whether it relates to hair cloning or multiplication.

      community What is the deal with "longitudinal partial follicular unit transplantation"

       5 upvotes 6 years ago
      Longitudinal partial follicular unit transplantation involves extracting part of the donor follicular unit, allowing the donor area to be overharvested without noticeable hair loss. The conversation questions if this method is practiced in clinics or if it's theoretical, and whether it relates to hair cloning or multiplication.

      community Transitioning off daily Oral Dutasteride (0.5mg) for long-term (multi-decade) maintenance. Which protocol is best?

      in Finasteride/Dutasteride  6 upvotes 1 month ago
      The conversation discusses transitioning from daily oral Dutasteride to a long-term maintenance protocol for hair loss, considering options like oral Finasteride with topical Dutasteride, pulsed oral Dutasteride, and oral Finasteride with topical Finasteride. The consensus suggests maintaining a baseline with daily Finasteride and using Dutasteride twice a week to minimize shedding while reducing systemic exposure.

      community A year on a new protocol: Oral Min and Dut

      in Treatment  30 upvotes 10 months ago
      The user followed a hair loss treatment using 2.5mg oral Minoxidil and 0.5mg oral Dutasteride daily. They initially tried a homemade topical Dutasteride but switched to capsules, achieving impressive results.