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GlossaryConcentration

amount of substance in a given volume

Concentration refers to the amount of a substance present in a given volume of solution or mixture. In the context of hair and biology, it could relate to the concentration of nutrients, chemicals, or medications applied to the scalp or hair follicles, which can influence hair growth and health. For example, a higher concentration of minoxidil in a topical solution might be more effective in treating alopecia, but it could also increase the risk of side effects.

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Tracking 1 products like 265 RU-58841 Solution 50mg/ml – 50ml from by companies like Chemyo. View product »

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community How to increase Pyri concentration from 0.5% to 1% wihout using more volume ( 2ml x 2 per say for example )

in Chat 6 upvotes 4 months ago

OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.

community tretinoin cream concentration question

in Treatment 12 upvotes 2 years ago

The conversation is about choosing the right concentration of tretinoin cream to enhance the absorption of minoxidil for hair loss treatment. The options discussed are 0.5, 0.05, 0.25, and 1mg/g concentrations.

community Are there stronger concentrations of fluridil out there yet?

in Treatment 6 upvotes 3 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. Question raised about stronger concentrations of Fluridil being available.

community Optimal topical (leave in, not shampoo) caffeine concentration. Contradictions across studies.

in Research/Science 13 upvotes 1 year ago

One study suggests a 0.2% caffeine concentration is nearly as effective as 5% minoxidil for hair loss, while other findings indicate that concentrations between 0.001% and 0.005% are more effective, with 0.001% being the most effective. There is no clear consensus on the optimal caffeine concentration for hair loss treatment.

community KX826 New Phase 3 Trial In China for 2025: 1.0% concentration

in Research/Science 60 upvotes 1 week ago

KX-826 is undergoing Phase III trials in China as a potential treatment for male pattern baldness, with some users considering it as an alternative or addition to finasteride and dutasteride. Opinions on its effectiveness vary, with some users reporting positive results and others finding it expensive and ineffective.

community People call companies stupid for making very high concentration Topical Fin solutions but I think they overlook the fact that the actual absorption rate of finasteride varies greatly

in Finasteride/Dutasteride 13 upvotes 10 months ago

The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.

community Fluridil status in 2022: User experiences and higher concentrations

in Research/Science 7 upvotes 2 years ago

Fluridil's effectiveness and safety in treating hair loss are discussed, with higher concentrations showing potential success. Comparisons are made to other treatments like RU58841, Pyri, CB-03-01, and topical spironalactone.

community Whats happening with Fluridil these days? Any higher concentrations easily available yet?

in Treatment 6 upvotes 3 years ago

Hair loss discussion focused on Fluridil treatment. Availability of higher concentrations questioned.

community About to add topical melatonin to my 5% minoxidil solution. What's would be the right concentration?

in Research/Science 15 upvotes 3 years ago

The user added melatonin to their 5% minoxidil solution for hair growth, using a concentration of 0.0033%, which equates to roughly 2mg for a 60ml bottle. They later reported no significant difference and planned to continue the treatment for a few more months before potentially stopping to observe any changes in shedding.

community If you could get for Christmas your own personalised topical anti hair loss serum that has the best the current science can offer, what would it contain and at what concentration?

in Treatment 2 upvotes 1 month ago

A personalized topical anti-hair loss serum could include high-dose setipiprant, high-dose CB 03-01, low-dose finasteride, minoxidil, latanoprost, and tretinoin. These ingredients are suggested for their potential effectiveness in promoting hair growth.

community pyrilutamide 0.5% vs. ru58841 5%? is RU stronger because of the higher concentration?

in Technology 3 upvotes 5 months ago

The conversation is about comparing the effectiveness of 5% RU58841 and 0.5% pyrilutamide for hair loss treatment. The user is asking if the higher concentration of RU58841 makes it stronger than the lower dose of pyrilutamide.

community Clascoterone (Winlevi) now approved in Canada

in Product 13 upvotes 1 year ago

The conversation is about the approval of Clascoterone (Winlevi) in Canada for hair loss treatment. One user expressed skepticism about its effectiveness due to low concentration.

community Does anybody else got their hair ruined when on tretinoin?

in Chat 4 upvotes 7 months ago

The user experienced hair shedding and follicle shrinkage when using retinoic acid, despite trying different concentrations and frequencies. The hair loss persisted for six months but regrew after stopping the treatment.

community Topical Finasteride strength discussion

in Research/Science 65 upvotes 11 months ago

The conversation discusses the effectiveness of different concentrations and dosages of topical finasteride on scalp and serum DHT levels, comparing it to oral finasteride and noting the side effects seem to be fewer at lower dosages. Participants shared experiences and referenced a chart indicating similar scalp DHT reduction with 0.025% topical finasteride as with 1mg oral finasteride, but with fewer side effects.

community Optimal dose for topical Melatonin

in Treatment 6 upvotes 1 year ago

The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

community Compounding Topical Melatonin at Home

in Treatment 7 upvotes 3 years ago

Melatonin at a 0.0033% concentration shows results for hair loss when used topically. A user is discussing how to replicate this by adding 2mg of Melatonin to 60ml of Minoxidil solution.

community Winlevi just got FDA approval, projected to be available early 2021 in the US

in Treatment 46 upvotes 4 years ago

The conversation is about creating a higher concentration of the newly FDA-approved hair loss treatment, Clascoterone (Winlevi), through compounding pharmacies and possibly organizing group purchases. Some users are unfamiliar with Winlevi and are asking for an explanation of the drug.

community What are your thoughts on this solution?

in Treatment 16 upvotes 3 weeks ago

The conversation discusses hair loss treatments, focusing on the use of Minoxidil, finasteride, and triamcinolone. Concerns are raised about high concentrations of Minoxidil and the long-term use of corticosteroids.

community Topical Dutasteride & Microneedling Works

in Finasteride/Dutasteride 6 upvotes 4 months ago

Topical dutasteride, especially at higher concentrations, can be effective for hair loss when combined with microneedling to enhance absorption. Users discuss the side effects of finasteride and dutasteride, with some preferring topical treatments to avoid systemic side effects.

community What’s the highest minox % you home brewed ?

in Minoxidil 2 upvotes 6 months ago

A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.

community anagenic pyrilutamide powder - help me understand the pricing

in Product 2 upvotes 7 months ago

The user is confused about the pricing and concentration of pyrilutamide powder for hair loss treatment. They calculate that 500mg of pyrilutamide can make ten 1ml applications of a 5% solution, costing $119.

community Topical Dutasteride 1% - High dosage?

in Finasteride/Dutasteride 6 upvotes 2 years ago

User asks about two topical dutasteride solutions and wonders if 1% concentration is overkill compared to 0.1%. They also consider trying standard topical dutasteride before using Minoxidil.

community 2 month progress on diluted hims spray.

in Progress Pictures 306 upvotes 9 months ago

A user diluted a Hims spray with Kirkland's minoxidil to lower finasteride concentration and has been applying it for nearly 3 months, noticing baby hairs at the temples. They also use a dermastamp, saw palmetto, and biotin supplements, and are seeking advice on their hair loss stage.

community Why nobody uses 0.25% (2.5mg/ml)?

in Treatment 66 upvotes 1 year ago

The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

community Finasteride sides on a microdose - what do I do next?

in Finasteride/Dutasteride 8 upvotes 2 years ago

User tried oral and topical finasteride for hair loss but experienced headaches and concentration issues. They ask for advice on whether to continue or try other treatments like alfatradiol, fluridil, or pyrilutamide.

community RU58841 and impact onmale fertility?

in Chat 2 upvotes 6 months ago

The conversation is about the potential impact of RU58841 on male fertility, specifically regarding sperm concentration, total count, and motility. The user is curious about the likelihood of RU58841 reducing fertility based on its mechanism of action and comparisons to similar substances.

community Pyrilutamide isn’t failed at all.

in Technology 10 upvotes 7 months ago

Kintor is producing a cosmetic with KX826, starting at 0.5% concentration and moving to 1%. The 0.5% concentration wasn't as effective as minoxidil and finasteride, but the 1% concentration shows promise.

community Where TF does one find a reputable source for Latanoprost/Bimatoprost??

in Treatment 3 upvotes 8 months ago

The conversation is about difficulty finding a reputable source for Latanoprost or Bimatoprost in pure powder form or high concentrations for hair loss treatment, with only low concentration solutions being readily available.

community Pyrilutamide 5 months results (before, after pics)

in Progress Pictures 193 upvotes 1 year ago

Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.