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Did you mean Clock Genes?

Glossary Clock Genes

genes regulating 24-hour biological rhythms in organisms

Clock genes, also known as circadian genes, are a group of genes that regulate the circadian rhythms in living organisms. These rhythms are roughly 24-hour cycles in physiological processes, such as sleep-wake cycles, hormone release, and metabolism. Clock genes produce proteins that interact in feedback loops to maintain these cycles, ensuring that biological functions are synchronized with the day-night cycle.

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community Minoxidil aint shit, genetics are dumb, i dont want to be bald

in Minoxidil 217 upvotes 11 months ago

Minoxidil alone is not effective for significant hair regrowth; combining it with finasteride or dutasteride is necessary. Additional treatments like hair transplants, microneedling, or oral medications are recommended for better results.

community 6 months Fin 1.25 mg Everyday. Dermastamp every 2 weeks 0.6mm. Very happy. Click the picture to see the full regrowth.

in Progress Pictures 180 upvotes 1 year ago

A user shared their positive experience with hair regrowth using finasteride 1.25 mg daily and dermastamping every two weeks. They reported no side effects and noticed regrowth after about three months.

community Do you consider Haircafe a trusted source of news/discussion?

in Chat 21 upvotes 1 year ago

Haircafe is generally trusted for hair loss information, particularly for his evidence-based approach and recommendations of finasteride, dutasteride, and minoxidil. While some users appreciate his scientific focus and lack of product promotion, others criticize his dismissal of anecdotal evidence and certain biases.

community Reminder: A NW2-3 or high hairline wasn’t considered “bald” or “cooked” until like 3 years ago

807 upvotes 1 year ago

Younger generations now view receding hairlines as baldness, increasing the use of treatments like minoxidil and finasteride. Social media and changing beauty standards have intensified focus on hairlines, altering perceptions of baldness.

community Finasteride vs Dutasteride, something ain’t right.

in Finasteride/Dutasteride 31 upvotes 11 months ago

Finasteride is generally seen as more successful for hair loss than Dutasteride, with fewer negative experiences reported. Dutasteride is considered more effective but often leads to more complaints, possibly due to higher expectations or improper use.

community How do you think Shah Rukh Khan maintains his full head of hair at 60?

453 upvotes 9 months ago

Shah Rukh Khan's hair at 60 is attributed to genetics, with speculation about using finasteride, minoxidil, or hair transplants. Some believe it's due to good genes, while others think he might use treatments or have had hair procedures.

community Circadian rhythm disruption and its potential impact on hair growth cycles

in Technology 7 upvotes 4 months ago

Poor sleep quality may affect hair growth cycles by disrupting the body's natural clock and stress hormones. The focus should be on improving sleep to support overall health, including hair growth, rather than relying solely on treatments like Minoxidil, finasteride, or RU58841.

community 2 years on finasteride - holding steady, but not much regrowth

in Progress Pictures 76 upvotes 5 months ago

The user has been on finasteride for two years, experiencing maintenance of hair without significant regrowth, and is considering adding minoxidil for potential improvement. They are generally satisfied with the results and are exploring other options like peptides and possibly a hair transplant in the future.

community Why do patients drop back to baseline/pre-treatment soon after quitting Finasteride?

in Research/Science 10 upvotes 10 months ago

Stopping finasteride often leads to rapid hair loss, returning to a genetic baseline, as the drug temporarily halts hair loss and promotes regrowth. The discussion explores the complexity of hair loss, suggesting that factors beyond DHT, such as genetics and scalp conditions, may play a role.

community 80-year-old with his 99-year-old father have more hair than I did at 15

1023 upvotes 6 months ago

An 80-year-old man and his 99-year-old father have more hair than many younger people, sparking discussions about hair loss and genetics. The suggested treatment for maintaining hair is simply eating oysters.

community Hair line Mount Rushmore. Bastards lol.

in Chat 851 upvotes 9 months ago

Hairlines and hair loss treatments like finasteride and hair transplants. Celebrities' hairlines are discussed, noting genetics and interventions.

community What can be the real reason of Finasteride SE ?

18 upvotes 1 year ago

Finasteride can cause side effects like erectile dysfunction and decreased libido, possibly due to increased estradiol from testosterone aromatization, especially in those with higher body fat. Side effects vary widely and may also be influenced by genetic factors or neurosteroid inhibition.

community Minoxidil 5% ONLY 3month progress

in Progress Pictures 966 upvotes 1 year ago

A 19-year-old saw significant hair regrowth using 5% minoxidil over three months, with only initial shedding as a side effect. They plan to continue minoxidil and may add finasteride to maintain results.

community Low level chronic allergies and hair loss

5 upvotes 2 years ago

Hair loss can be influenced by chronic low-level allergies, and treatments like fexofenadine or topical cetirizine may help with regrowth. The user avoids finasteride, dutasteride, and minoxidil, and has tried Regenera Activa and PRF sessions.

community I stopped taking Finasteride because of side effects, and my dermatologist prescribed Dutasteride.

13 upvotes 1 week ago

The user stopped taking finasteride due to erectile dysfunction and was prescribed dutasteride by a dermatologist. Some users shared experiences of having fewer side effects with dutasteride, while others warned it might cause similar or worse side effects.

community 6 years on Fin. This shit is goated.

143 upvotes 4 months ago

Finasteride is effective for maintaining hair and stopping hair loss, with many users experiencing long-term success and minimal side effects. Some users consider switching to Dutasteride or adding Minoxidil for additional regrowth.

community Guys I actually can’t believe pyrilutamide is actually working!!

29 upvotes 4 months ago

Hair regrowth was achieved using minoxidil, nizoral, alfatrodial, and pyrilutamide after finasteride caused side effects. The user recommends this combination for those who can't tolerate 5AR inhibitors, stressing consistent use.

community Other factors involved then DHT/5aR

5 upvotes 3 months ago

DHT is the primary cause of hair loss, but factors like diet, stress, and lifestyle can influence its severity. Treatments like finasteride and dutasteride target DHT, while maintaining overall health is also important.

community Scalp hydration's surprising link to hair growth cycle regulation

in Technology 23 upvotes 4 months ago

Scalp hydration may influence hair growth by affecting the signaling pathways that control the hair growth cycle. Users suggest using facial moisturizer, aloe vera, and oils for scalp hydration.

community Clascoterone - what we have right now

24 upvotes 6 months ago

Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

community Intermittent fasting triggers hair loss in study (suppresses hair follicle regeneration)

in Research/Science 241 upvotes 7 months ago

Intermittent fasting may suppress hair follicle regeneration, but opinions vary on its impact on hair loss. Some users report no negative effects or even hair improvement while using treatments like finasteride and minoxidil.

community 14 Month Progress w/ Topical Fin+Min

986 upvotes 2 years ago

A user shared 14-month progress pictures using topical finasteride and minoxidil for hair loss. Others commented on the impressive results and asked about age, improvement timeline, and how to obtain finasteride.

community Finasteride x Minoxil Topical Hair Loss

in Finasteride/Dutasteride 9 upvotes 3 weeks ago

The user is using a combination of finasteride, minoxidil, ketoconazole, pumpkin seeds, laser therapy, PRP, dermaroller, and vitamins for hair loss. They are advised to switch to oral finasteride and be patient, as results may take up to a year, with a hair transplant as a potential future option.

community 22M, 6 months progress. No finasteride, no oral meds. Topical only.

in Progress Pictures 23 upvotes 5 months ago

A 22-year-old shared their 6-month hair loss progress using only topical treatments like minoxidil, derma rolling, and red light therapy, without finasteride or oral medications. Other users suggested adding DHT blockers like RU58841 and ketoconazole shampoo for better results.

community Switching from Finasteride to Dutasteride... probably

in Finasteride/Dutasteride 16 upvotes 5 months ago

A 26-year-old male is considering switching from Finasteride to Dutasteride for more effective hair restoration, while others share experiences and advice on transitioning between these treatments. Many suggest gradually integrating Dutasteride with Finasteride to avoid shedding, and some report positive results with Dutasteride, though regrowth is not guaranteed.

community 27M 1.25 fin 5 months, 1ml 5% min 2x daily 2 months

107 upvotes 6 months ago

A 27-year-old male has been using 1.25mg finasteride for 5 months and 5% minoxidil twice daily for 2 months, along with biotin and vitamin D supplements, to improve hair growth. He reports some progress and side effects like reduced libido, and is considering switching to oral minoxidil and possibly adding dutasteride after a year.

community Progress after 4 years of Fin?

in Is this regrowth? 187 upvotes 1 year ago

The user experienced hair regrowth and thicker hair after using finasteride daily for four years and recently added topical minoxidil. They are considering derma stamping but are cautious about switching to dutasteride due to potential side effects.

community PP405 Phase 2a press release with early results

700 upvotes 1 year ago

PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.

community You NEED this if You’re Taking Fin/Dut

in Finasteride/Dutasteride 1 year ago

DIM is suggested to help with estrogen metabolism for those on finasteride or dutasteride, potentially reversing side effects like fat gain and mood changes. Some users doubt its effectiveness, recommending lifestyle changes or consulting a doctor instead.

community 18 month hairline progress pictures.

in Progress Pictures 818 upvotes 1 year ago

A user's 18-month hairline progress using minoxidil, finasteride, Nizoral, microneedling, and scalp massage. They share their routine and discuss treatment effectiveness and photo order confusion.