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      community The Cure isn't 5 years away; it's already here.

      in Research/Science  998 upvotes 1 month ago
      PP405 is a new topical treatment for hair loss, showing promise in trials but still requires finasteride for maintenance. There is skepticism about its effectiveness and safety, with concerns about needing finasteride to maintain results.

      community Does RU work? I see people buying it and reporting success, but if so why was it discontinued?

      in Treatment  3 upvotes 2 months ago
      RU58841 is a controversial hair loss treatment with mixed reviews; some users report success, often in combination with other treatments like finasteride or minoxidil, while others experience side effects like chest pain. The treatment's discontinuation is speculated to be due to patent expiration and lack of profitability, despite some users continuing to use it as part of a broader regimen.

      community Does dutasteride stop hair loss forever?

      in Finasteride/Dutasteride  38 upvotes 2 months ago
      Dutasteride and finasteride can significantly slow or halt hair loss, with some users experiencing regrowth, but results vary. Lifestyle factors and individual genetic predispositions also play a role in hair loss outcomes.

      community Upcoming treatment ideas in the future

      in Research/Science  10 upvotes 3 months ago
      Exploring future hair loss treatments, including immunosuppressants for hair transplants and hair cloning, with a focus on leveraging research from other medical fields. Current treatments like finasteride and minoxidil are effective for most, but there's a call for more funding and innovation in the hair loss industry.
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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 5 months ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Why is it "not right" to start off with Dutasteride?

      in Finasteride/Dutasteride  60 upvotes 7 months ago
      The conversation discusses whether it's better to start hair loss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.

      community Is getting on Dut at 21 a bad idea after taking Fin since 18?

      in Chat  7 upvotes 7 months ago
      A user is considering switching from finasteride to dutasteride for hair loss at age 21, worried about potential side effects on bone and brain development. Another user shared their positive experience with dutasteride, noting minimal body hair and no side effects.

      community The three stages of a man's life...

      in Satire  853 upvotes 9 months ago
      The conversation is about men discussing their experiences with hair loss and their acceptance or resistance to it, mentioning treatments like finasteride and hair transplants. Some users express hope to maintain their hair while young, while others have accepted baldness or found confidence after shaving their heads.

      community New Study Fails to Show Benefits of Microneedling in Males with Balding.

      in Treatment  157 upvotes 1 year ago
      A new study suggests microneedling alone doesn't benefit male balding, but users argue the study's methods differ from common practices, like combining microneedling with minoxidil and using more frequent treatments. Some believe the study's short duration and infrequent sessions are inadequate to assess microneedling's effectiveness.

      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 1 year ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

      community Tretinoin Efficacy Alone for Hair Regrowth + DHT blocker

      in Minoxidil  5 upvotes 1 year ago
      Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.

      community Sharing my (relatively short) Success Story

      in Progress Pictures  77 upvotes 1 year ago
      A user named "paulsac11" shares their success story of treating hair loss. They started with topical minoxidil, then switched to oral minoxidil and dutasteride. They also used a shampoo and conditioner from Keeps. After eight months of treatment, they have seen significant improvement in their hairline.

      community How do we only have two treatments to combat hair loss at this point in time?

      in Chat  211 upvotes 1 year ago
      The post discusses frustration over the limited and not always effective treatments for hair loss, mainly Minoxidil and Finasteride. The conversation includes mentions of potential new treatments like GT20029, HMI-115, CosmeRNA, KX-826, and microneedling, but also highlights the challenges of funding and prioritizing research in this area.

      community Why we need to be more open as men

      in Chat 1 year ago
      The emotional difficulty of hair loss for men and how society can be more understanding; various methods to address hair loss, such as finasteride, minoxidil, and RU58841; and why it is important to normalize caring about one's looks.

      community New Latanoprost-Based Formula Used by Hollywood Celebrities

      in Treatment  26 upvotes 2 years ago
      A new Latanoprost-based formula used by Hollywood celebrities to treat hair loss, with the formula containing minoxidil, tretinoin, melatonin, azelaic acid, zinc thymulin, vitamin B6, sandalore and methyl vanillate. It also mentions the potential of offering a combined sublingual minoxidil/oral dutasteride option in the future.

      community 6.5 Month Progression 33/Female

      in Female  43 upvotes 2 years ago
      Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

      community Are there alternatives to finasteride?

      in Research/Science  12 upvotes 2 years ago
      The conversation is about seeking alternatives to finasteride for hair loss treatment due to concerns about sexual side effects, with pyrilutamide mentioned as a potential alternative.

      community Pyrilutamide real life results?

      in Research/Science  15 upvotes 2 years ago
      The results of using Pyrilutamide, a hair loss treatment available on the gray market, and other treatments such as Minoxidil, Finasteride and RU58841.

      community Pyrilutamide - one month update

      in Update  14 upvotes 2 years ago
      User on 5th week of Pyrilutamide and oral Minoxidil, no hair loss improvement yet. Others suggest waiting 3 months for results.