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GlossaryChronic Graft-Versus-Host Disease

condition where transplanted cells attack recipient's body long-term

Chronic Graft-Versus-Host Disease (cGVHD) is a condition that can occur after a stem cell or bone marrow transplant, where the donated cells (the graft) attack the recipient's body (the host). This immune response can lead to long-term complications affecting various organs, including the skin, liver, and gastrointestinal tract, and can manifest as rashes, liver dysfunction, and digestive issues.

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 100 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Received a hair transplant today at 22 years old

in Transplants 108 upvotes 5 years ago

A 22-year-old's experience with receiving a hair transplant and the use of Minoxidil, finasteride, RU58841, Lidocaine shots, and platelet injections to treat hair loss.

community Destined for Baldness; there’s one thing that made the difference

in Microneedling 58 upvotes 1 year ago

User fought hair loss with Derminator microneedling, topical and oral minoxidil, and a 2000 FUE hair transplant. Derminator was a game changer, preventing further loss.

community The celebrated doctors that we adore so much and whose advice we hear without doubts, are only humans after all

in Finasteride/Dutasteride 2 upvotes 5 months ago

The user visited three dermatologists for hair loss treatment and was disappointed with their lack of thorough examination and discussion. Treatments prescribed included minoxidil, finasteride, multivitamins, ketoconazole shampoo, vitamin D3, and biotin, but the user was dissatisfied with the approach and lack of consideration for newer treatments.

community Post Finasteride Syndrome, A dangerous lie.

in Chat 142 upvotes 5 months ago

A user initially had side effects from finasteride, attributed them to anxiety and the nocebo effect, and after resuming the drug, experienced positive effects and now warns against misinformation about Post Finasteride Syndrome.

community Topical is superior to oral in terms of results (my theory)

in Finasteride/Dutasteride 59 upvotes 4 months ago

The conversation discusses the use of topical minoxidil and finasteride for hair loss, with some users combining them with oral treatments. Users share their experiences and opinions on effectiveness, cost, and convenience, with mixed views on whether topical or oral applications are superior.

community What was your “f*ck I’m balding” story?

in Chat 178 upvotes 1 year ago

User noticed thinning hair at 18-19, started finasteride at 22 and minoxidil at 24, with positive results. Others shared hair loss experiences and treatments, including finasteride, minoxidil, and hair transplants.

community 8 months apart on the mother of all stacks

in Progress Pictures 149 upvotes 1 year ago

User Tricky9555 tried various hair loss treatments for 8 months with no visible results. Others suggested considering a hair transplant, checking thyroid levels, and being patient for up to 24 months for potential results.

community Opinions on Scalp fibrosis and DHT?

in Research/Science 9 upvotes 2 years ago

The conversation discusses the theory that scalp fibrosis contributes to male pattern baldness (MPB) by increasing DHT concentration, and mentions treatments like Minoxidil. The user seeks opinions on the theory and the effectiveness of scalp massages.

community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering

in Finasteride/Dutasteride 191 upvotes 2 years ago

Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.

community Low level chronic allergies and hair loss

in Research/Science 6 upvotes 7 months ago

Hair loss can be influenced by chronic low-level allergies, and treatments like fexofenadine or topical cetirizine may help with regrowth. The user avoids finasteride, dutasteride, and minoxidil, and has tried Regenera Activa and PRF sessions.

community A lot of hair falling out like this, what does it mean? Diffuse thinning, chronic dandruff and scalp crust (seborrheic dermatitis), 28 y/o male

in Research/Science 35 upvotes 1 year ago

A 28 year old male experiencing diffuse thinning, chronic dandruff and scalp crust (seborrheic dermatitis), with replies discussing the use of topical fin for hormone imbalances and Nizoral for seb derm.

community Finally decided to buzz my head after experiencing hair loss since I was 17 (23 now). I think it looks decent, swipe to see what I was rocking before during the pandemic. Who knows maybe I’ll hop on fin but as someone who struggles with chronic fatigue and low test I’m hesitant.

in Shaved/buzzed 326 upvotes 1 year ago

A user's decision to shave their head after experiencing hair loss since the age of 17, and discussion around the potential use of Fin for treating hair loss.

community 26F Thinner hair due to vitamin deficiencies?

in Female 12 upvotes 7 months ago

A female user with chronic anemia and vitamin deficiencies is experiencing finer, straighter hair and seeks recommendations for scalp products to improve circulation and prevent potential hair thinning. She is considering growth oils but is unsure of their effectiveness.

community Has anyone figure out how to deal with their itchy scalp when most ingredients aren't working?

in Treatment 6 upvotes 2 years ago

The user has chronic itchy scalp and dandruff, unresponsive to ketoconazole, selenium sulfide, zinc pyrithione, coal tar, and salicylic acid. Topical steroids were also ineffective for long-term use.

community 1 and a half years on fin - hair is way worse.

in Finasteride/Dutasteride 9 upvotes 1 year ago

The user reported worsening hair loss after 1.5 years on finasteride, questioning if chronic iron deficiency could be a cause. They noted no side effects from finasteride.

community Correlation between topical retinoids and diffuse hair loss

in Research/Science 7 upvotes 2 years ago

Excess Vitamin A and topical retinoids can cause diffuse hair shedding. The user suspects their chronic telogen effluvium may be linked to using adapalene, a topical retinoid.

community Looking for suggestions on vitamins

in Female 5 upvotes 2 months ago

A user is seeking affordable hair vitamins without biotin, already taking zinc and D3+K2, and has been dealing with chronic telogen effluvium since 2013. They previously used Nutrafol Vegan but found it too expensive.

community Anger and frustration as I finally learn my diagnosis.

in Female 8 upvotes 1 year ago

A young female diagnosed with Lichen planopilaris (LPP) experienced years of misdiagnosis and ineffective treatments, including a hair transplant and other procedures. She is considering litigation due to the misdiagnosis and has learned that LPP is chronic, hair loss can be stopped with ongoing medication, but lost hair cannot regrow.

community 19 year old male and Finasteride

in Treatment 7 upvotes 2 years ago

A 19-year-old male with hair loss and gynecomastia is considering starting finasteride after trying various treatments like Ketoconazole shampoo and consulting dermatologists. He has chronic telogen effluvium and seborrheic dermatitis, with normal testosterone and thyroid levels but low platelet count.

community My Experience and a Discourse on "DUPA"

in Treatment 8 upvotes 2 months ago

The user discusses their hair loss experience, exploring various hypotheses including thyroid levels, vitamin D, DHEA, nutritional deficiency, diabetes, seborrheic dermatitis, lack of nutrition to hair follicles, chronic inflammation, female pattern hair loss causes, cortisol, and prolactin levels. They are currently using finasteride, beta-sitosterol, and have tried topical dutasteride and microneedling therapy.

community Rosemary oil, peppermint oil, mucuna pruriens – two weeks in

in Treatment 85 upvotes 1 year ago

A user who is trying alternative treatments, such as mucuna pruriens dissolved in water/alcohol and a blend of jojoba oil, rosemary oil, and peppermint oil, for hair loss. Other users have shared anecdotal evidence, discussed the potential effectiveness of certain treatments, and questioned the time sensitivity of experimenting with new treatments.

community Is there a possibility it's only because of the SD

in Ketoconazole 3 years ago

A user is experiencing severe hair loss, diagnosed with seborrheic dermatitis, and is using Ketoconazole and beclomethasone. They are concerned about potential female pattern baldness and are seeking reassurance and advice.

community Is it too late to regrow my hair?

in Question 13 upvotes 4 years ago

A 29 year old female with hair loss issues that have been linked to PCOS; the user has started taking Spironolactone and iron supplements in hopes of regrowing their hair, but is wondering if it's too late.

community Dont know what the hell is going on.

in Chat 6 upvotes 1 month ago

The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.

community 5ar alpha reductase stimulation is different depending on whether it’s type 1 or 2

in Hair Systems 16 upvotes 1 year ago

The conversation discusses how different factors can stimulate type 1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.

community 2 years update [finasteride and 5 mg oral minoxidil

in Progress Pictures 125 upvotes 1 year ago

User shared 2-year hair loss progress using finasteride 3 times a week and 5 mg oral minoxidil daily. Another user praised the results as a complete recovery.

community Is there an improvement? Zinc, biotin, and D3

in Is this regrowth? 7 upvotes 1 year ago

The conversation discusses hair regrowth improvement due to zinc, biotin, and D3 supplements, highlighting that hair loss can result from deficiencies, not just androgenetic alopecia. The user emphasizes that treatments like finasteride are not the only solutions.

community 6.5 Month Progression 33/Female

in Female 44 upvotes 1 year ago

Maintaining scalp hair and minimizing shedding, treatments used such as Procapil, supplements, topical caffeine, topical estrogen, and scalp massage; suggestions for anagen extenders or pharmaceuticals to help with a short anagen phase.

community Topical caffeine is a common ingredient in formulas to prevent hair loss and to induce hair regrowth. (What’s your take on this?)

in Treatment 12 upvotes 1 year ago

The conversation discusses whether topical caffeine is effective for hair loss, with some users questioning its role due to its vasoconstrictive and vasodilative properties, while another suggests that temporary vasoconstriction might be beneficial by promoting angiogenesis. Specific treatments mentioned include caffeine shampoo, which one user believes is ineffective.