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      community RU58841 is the only thing that worked for me, a DUPA sufferer

      in Treatment  1 upvotes 1 year ago
      RU58841 was the only treatment that slowed hair loss and reduced irritation for a DUPA sufferer after trying finasteride, minoxidil, and dutasteride with no success. The user continues using 6mg oral minoxidil, 0.5mg dutasteride, and an 8% RU58841 solution.

      community Cypro to reverse hairloss + Fin?

      in Treatment 1 year ago
      The conversation discusses using cyproterone temporarily to reverse hair loss, followed by finasteride to maintain regrowth. Concerns about cyproterone's side effects, such as lowering testosterone and potential health risks, are raised, with alternatives like spironolactone suggested for androgen-related issues.

      community What’s your views on clascoterone 5% topical solution by cosmo

       23 upvotes 9 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 1 year ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community RU58841 User Feedback - How many of you has it helped

       31 upvotes 4 years ago
      RU58841 has helped many users reduce hair shedding and improve hair thickness, with some experiencing side effects like libido changes. Users often combine it with other treatments like minoxidil, finasteride, and ketoconazole shampoo for better results.

      community KX-826 users: 0.5% vs 0.9% vs foam

      in Technology  6 upvotes 1 year ago
      KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.

      community Ben Greenfield Podcast : CHK-Cu & C-60

       4 upvotes 5 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.

      community Success without fin/dut??? Anyone? Please help :(

       4 upvotes 4 years ago
      The conversation discusses alternatives to finasteride for hair loss, including topical treatments like minoxidil, RU58841, CB-03-01, and dutasteride. Users also mention other options like alfatradiol, topical caffeine, and mesotherapy, while expressing concerns about side effects and the effectiveness of these treatments.

      community RU58841 works great!

       7 upvotes 5 years ago
      RU58841 stopped hair shedding and increased hair density for the user, who experienced side effects from finasteride. The user's regimen includes RU58841, minoxidil, microneedling, Nizoral, and plans to add castor oil.

      community Should I get back on RU58841??

       6 upvotes 3 months ago
      The conversation discusses whether to resume using RU58841 for hair loss, as the user is already on finasteride but noticing visible scalp. Users suggest continuing RU58841 despite its cost if it boosts confidence, and some mention considering minoxidil or other treatments.

      community Androgen degraders for hair loss

       61 upvotes 2 years ago
      The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 7 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community RU58841 Permanently Fixed Balding In Unexpected Way.

      in Satire  123 upvotes 10 months ago
      The user humorously describes trying various hair loss treatments, including minoxidil, finasteride, and RU58841, with a satirical twist involving psychedelic experiences and imaginary entities. They mistakenly used LSD instead of RU58841 and plan to continue experimenting with other substances.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community KX-826 1% Phase II Results from China Just Dropped

       37 upvotes 1 year ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community I wrote a poem about pp405 (potential treatment)

      in Satire  19 upvotes 1 year ago
      A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

      community ru58841, where can I get some?

       3 upvotes 5 months ago
      The conversation is about finding a source for RU58841 in Canada as an additional treatment for hair loss, alongside oral minoxidil and dutasteride. Alternatives like kx826 are suggested, with some users discussing prices and sources for these products.

      community Where to get RU in Germany without shipping from other countries?

       4 upvotes 1 month ago
      The conversation discusses obtaining RU58841 in Germany without international shipping, with users sharing experiences and advice. The original poster has been using RU58841 for three years and is seeking local sources to avoid customs issues.

      community KX-826 Phase 3 Failed. Sorry guys...

       51 upvotes 2 years ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Is RU58841 making a comeback? Is it worth it?

       5 upvotes 1 week ago
      RU58841 is being reconsidered as a hair loss treatment, with some users reporting early positive signs, though concerns about potential heart issues exist. Alternatives like KX826 and traditional treatments like dutasteride and minoxidil are also discussed.