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      community Anyone had similar experience ?

       4 upvotes 8 months ago
      The user experienced rapid diffuse hair thinning and is questioning if a vitamin D level of 32 could be the cause. They noticed a sudden loss of hair volume and density over 1-2 months.

      community Vitamin D supplementation causing hair shedding?

       4 upvotes 8 years ago
      The conversation discusses hair shedding potentially linked to vitamin D supplementation after Accutane use, with the user suspecting telogen effluvium. Others suggest the hair loss might not be related to vitamin D, considering it a coincidence.

      community Bicalutamide and muscles growth

       7 upvotes 1 year ago
      A 30-year-old woman with androgenetic alopecia is considering bicalutamide to slow hair loss but is concerned about its impact on muscle growth due to its anti-androgen effects. Alternatives suggested include dutasteride, spironolactone, RU58841, and minoxidil, with concerns about bicalutamide's side effects.

      community Vitamin D deficiency - could it be the cause?

      in Update  6 upvotes 1 year ago
      The user is experiencing hair thinning and has a vitamin D deficiency, which they suspect might be causing the issue, but they are also considering androgenic alopecia (AGA) as a cause. They are currently using minoxidil and are unable to get finasteride prescribed, while others suggest addressing the vitamin D deficiency and consulting a dermatologist.

      community STUDY: NAD⁺ Precursors + EGCG Increased Hair Density

       8 upvotes 6 months ago
      NAD⁺ precursors and EGCG may increase hair density, but users report mixed results with no significant hair gains. Some users suggest combining these with finasteride or dutasteride for better results.

      community Locklabs + Dutasteride Formula

       1 upvotes 8 months ago
      The conversation discusses the effectiveness and value of a Locklabs pill containing finasteride, minoxidil, biotin, and a low dose of dutasteride for hair loss. The user is uncertain if the .1mg dutasteride dosage is sufficient and worth the cost.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

       15 upvotes 7 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Experience with CB (Breezula)?

       4 upvotes 6 years ago
      CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

      community Vitamin E and K deficiency (F,25)

      in Research/Science  3 upvotes 4 months ago
      Vitamin E and K deficiencies due to exocrine pancreatic insufficiency may affect hair growth. A scalp biopsy is recommended to check for autoimmune-related hair loss.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

       5 upvotes 2 years ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Is the Cecred line actually legit or are people lying to us?

      1 year ago
      Cecred hair drops, containing keratin and biotin, are questioned for their effectiveness compared to proven treatments like minoxidil. Users express skepticism, suggesting deceptive marketing and the possibility of undisclosed use of other treatments like finasteride.

      community Better Than Minoxidil? Topical Sodium Valproate

       50 upvotes 1 year ago
      Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

      community Mineral deficiencies vs MPB vs Thyroid

       8 upvotes 1 year ago
      The user experienced hair improvement using a topical finasteride, minoxidil, and tretinoin combo, along with supplements like zinc, copper, magnesium, vitamin D3, K2, iodine, and boron. They believe these changes are due to addressing mineral deficiencies and possibly thyroid issues, despite skepticism from others.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community Rare case: AGA recovery with vitamin D alone (case study)

       51 upvotes 5 months ago
      Vitamin D deficiency can hinder hair recovery, and addressing it may help with hair loss. Hair loss may result from various issues like excess DHT, vitamin deficiency, or scalp inflammation.

      community 18M- doctor surprised to see how I am still able to move

      in Treatment  27 upvotes 8 months ago
      The conversation discusses hair thinning and the potential role of vitamin D deficiency in hair loss, with suggestions to take vitamin D3 supplements. The user also mentions having diffuse thinning and a slightly receding hairline.

      community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

       17 upvotes 8 months ago
      ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.

      community My final attempt at creatine with fin

       43 upvotes 1 year ago
      Creatine may cause hair shedding and texture changes, with mixed user experiences. Combining creatine with finasteride doesn't always prevent these effects, possibly due to individual DHT sensitivity.

      community Experiences with CB-03-01?

       5 upvotes 10 years ago
      CB-03-01 is considered too costly and lacks a proper delivery method, making it less viable compared to RU58841, which has shown effectiveness with minimal side effects. Finasteride caused a drop in libido for one user.

      community Creatine and ru-58841 experiences?

       1 upvotes 1 year ago
      RU58841 is preferred over finasteride for blocking DHT on the scalp, especially for those with aggressive MPB. Creatine is associated with increased hair shedding, even when using RU58841.

      community Second shed and more abnormalities

      in Treatment  1 upvotes 2 years ago
      The user has been using oral finasteride for 15 months and oral minoxidil for 6 months, and developed alopecia areata, for which a dermatologist prescribed calcipotriol/betamethasone. The treatment is helping, but the user is experiencing another shedding phase and is concerned about the effects of the steroid cream and the cause of hair loss.

      community Has anyone tried CB-01-03 aka Clascoterone?

       2 upvotes 6 months ago
      Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.

      community Vitamin D and Thinning

       5 upvotes 7 years ago
      The conversation discusses hair thinning and potential treatments, focusing on vitamin D supplements and their effects. Other suggestions include zinc, a high-protein diet, and coconut oil for hair health.

      community Creatine increases DHT?!?!

       8 upvotes 5 years ago
      Creatine may increase DHT, potentially affecting hair loss, but opinions vary. Users discuss using finasteride and alternatives like plant protein to manage hair loss.

      community fluridil (topilutamide) vs. cb-03-01 (clascoterone)

       4 upvotes 2 years ago
      The conversation is about comparing the effectiveness of fluridil and clascoterone in preventing hair loss and inquiring about their use as standalone treatments. There is a question about the concentration of the fluridil brand for efficacy.