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GlossaryAntioxidant Activity

neutralizes free radicals to prevent cellular damage and aging

Antioxidant Activity refers to the ability of certain substances to neutralize free radicals, which are unstable molecules that can cause cellular damage and contribute to aging and diseases, including hair loss and alopecia. These substances, known as antioxidants, help protect cells by donating electrons to free radicals, thereby stabilizing them and preventing oxidative stress. This property is crucial in maintaining overall cellular health and can be found in various vitamins, minerals, and plant compounds.

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community Does melatonin dissolve in isopropyl alcohol

in Technology 6 upvotes 1 year ago

The conversation discusses making a topical melatonin solution for hair loss treatment, questioning if isopropyl alcohol can dissolve melatonin. Melatonin is soluble in lipids and alcohol, but it's unstable and should be mixed fresh regularly; it may help hair growth by affecting certain cellular signaling pathways and has anti-androgenic effects.

community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

in Treatment 7 upvotes 4 years ago

Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Interested about what other adjunct therapies people are trying & whats working?

in Treatment 7 upvotes 7 months ago

The conversation discusses alternative hair loss treatments beyond the commonly used Minoxidil and Finasteride. One user is trying diclofenac gel, caffeine + antioxidant serum, finasteride, ketoconazole shampoo, and has stopped using Minoxidil due to ineffectiveness, while another user has adopted lifestyle changes like exercise, diet, stress reduction, and topical caffeine, along with scalp massages and microneedling.

community Bryan (the guy who reversed aging) shares treatment that reversed his hair loss

in Treatment 1066 upvotes 3 weeks ago

A person improved hair loss from Norwood 3 to Norwood 2 using a topical formula with minoxidil, dutasteride, and tretinoin, plus oral minoxidil and red light therapy. There is skepticism about the treatment's effectiveness and concerns about misleading comparison photos.

community What supplements or extra dtuff do you guys do for your hair?

in Product 2 upvotes 2 months ago

OP uses multivitamins, collagen, biotin, keratin, omega-3, satin bonnet, dandruff shampoo, oil moisturizer, and sun exposure for hair care. Users suggest adding antioxidants, probiotics, pumpkin seed oil, vitamin D, iron, and dermastamping.

community Anybody using topical melatonin or zix in 2024?

in Chat 12 upvotes 5 months ago

The conversation is about using topical melatonin or zix for hair loss without affecting hormones. The user is seeking advice on which treatment is more effective.

community experimenting with vitamin D3 in alcohol/oil topically only

in Research/Science 6 upvotes 1 year ago

Hair is growing faster after 2 weeks of using topical vitamin D3 in alcohol/oil. The user plans to continue the experiment for 3 months before giving a full review.

community Has anyone tried KeraXL before?

in Treatment 1 upvotes 1 year ago

A user discussed using KeraXL serum for hair loss, which contains Biochanin-A from Red clover extract and Acetyl Tetrapeptide-3. They sought feedback on its safety and effectiveness.

community C60 + microneedling – on off days from Pyrilutimide

in Microneedling 1 upvotes 1 year ago

User discusses using C60 serum with microneedling at 1.75mm and asks if it's safe. Current routine includes daily Pyril on temples, weekly microneedling, and C60 serum on non-Pyril days.

community Minoxidil Sulfate makes everyone a responder

in Research/Science 249 upvotes 5 days ago

Minoxidil sulfate is more effective than regular minoxidil, especially for those with low sulfotransferase levels or scalp sensitivity, but it is unstable unless delivered in a liposomal format. Combining minoxidil with tretinoin can enhance effectiveness, and stopping minoxidil use can lead to rapid hair loss.

community Obviously, all of us who are serious take antiandrogens and growth stimulants - what else are you doing lifestyle wise, dietary wise, and regiment wise to maximize your results?

in Treatment 21 upvotes 4 months ago

The user follows a hair loss treatment routine including Propecia, oral minoxidil, ketoconazole, and plans to switch to dutasteride. They also focus on lifestyle changes, dietary supplements, and are considering laser therapy.

community One year progress on fin and min

in Progress Pictures 176 upvotes 5 months ago

A user shared one-year progress using finasteride and minoxidil for hair loss at age 42. Suggestions included adding dermastamping, microneedling, and considering a hair transplant for further improvement.

community 10 months CB and Oral Minoxidil

in Progress Pictures 112 upvotes 7 months ago

A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

community Does drinking coffee offset the effects of Minoxidil?

in Minoxidil 16 upvotes 7 months ago

The conversation discusses whether drinking coffee affects the hair growth benefits of Minoxidil, with one user mentioning that Minoxidil's vasodilation is stronger than caffeine's vasoconstriction, and another sharing personal experience of better hair growth after quitting caffeine while on Minoxidil.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 61 upvotes 7 months ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

community Has anyone tried the New Nordic Hair Gro tablets?

in Product 2 upvotes 11 months ago

The conversation discusses the effectiveness of New Nordic Hair Gro tablets for hair loss. Specific treatments mentioned include Minoxidil, Finasteride, and RU58841.

community (26M) My 3 months progress on hair loss treatment. Extremely happy with the results. I have included so many details about my stack, my experience during the treatment, progress pictures, and everything I did during this time period.

in Progress Pictures 27 upvotes 1 year ago

A user's 3-month progress report on their treatment of hair loss using a stack of finasteride, dutasteride, and minoxidil, with additional supplements, diet and workout routine, and before-and-after photos.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Scientific Review: Saw Palmetto is not effective for treating hair loss and does not inhibit DHT to the extend that most people think. Anti-Hair loss claims are invalid.

in Research/Science 35 upvotes 2 years ago

Saw Palmetto is not effective for hair loss treatment and is not a recommended alternative to finasteride due to its inability to significantly inhibit DHT.

community Anyone here get results from topical melatonin?

in Research/Science 11 upvotes 2 years ago

A user has been using finasteride and minoxidil for hair loss but is experiencing increased shedding and is considering using topical melatonin with a product called Rizn. Another user is skeptical about the effectiveness of topical melatonin due to issues with the research and lack of replication of results, while a third user expresses interest in the outcome of using Rizn after not seeing results from topical finasteride and minoxidil.

community Triple Hair TH-16 released. Thoughts and opinions?

in Product 35 upvotes 3 years ago

Triple Hair's TH-16, a product claimed to be more effective than Minoxidil 5%, has been released; it contains melatonin and resveratrol. One user reported success with topical melatonin and dermarolling.

community What's the consensus about Minoxidil and skin aging/effects?

in Minoxidil 8 upvotes 4 years ago

The conversation discusses concerns that Minoxidil may cause skin aging, like collagen depletion and puffier faces. Some users suggest that a good skincare routine or collagen supplements might prevent these effects.

community We don't talk about vitamin E enough

60 upvotes 5 years ago

A user shared that taking vitamin E, specifically tocotrienols, seemed to reduce their hair shedding, and they are also using finasteride, minoxidil, and derma rolling for hair loss. Another user cautioned against high doses of vitamin E due to potential health risks.

community 35% regrowth brothers and sisters! More effective than Minox and Fin?

in Treatment 107 upvotes 6 years ago

A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

community Castor oil without using penetration enhancer after microneedling?

in Question 9 upvotes 6 years ago

The conversation is about whether castor oil can be effectively used alone after microneedling without a penetration enhancer like DMSO or ethanol. The user believes microneedling-induced wounds might be enough for absorption.

community Everything you need to know about KX-826 product (pyrilutamide)

in Product 19 upvotes 3 months ago

The post and conversation discuss KX-826 (pyrilutamide) for hair loss treatment, with positive remarks about its advertising and authenticity in China. The user changed their perspective after further research and seeing genuine advertising.

community Bryan Johnson just dropped his anti hair loss formula

in Treatment 338 upvotes 9 months ago

Bryan Johnson shared his hair loss treatment, which mainly relies on minoxidil and finasteride. Some users are skeptical of his results, while others appreciate his efforts in anti-aging and hair loss research.

community Started aggressively losing my hair at 16 and I'm now 30

in Progress Pictures 835 upvotes 1 year ago

The user started losing their hair at 16 and got a hair transplant. They used Minoxidil and finasteride as treatments. The transplant has held up well and they have not experienced graft loss.

community 9 months fin 0.33mg daily - everything’s coming up millhouse

in Progress Pictures 81 upvotes 1 year ago

User started oral finasteride 0.33mg daily and later made a topical solution with cetirizine and stemoxydine. They experienced hair growth progress after 8-9 months and discussed factors affecting their results.