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GlossaryAntioxidants

molecules that neutralize free radicals to prevent cell damage

Antioxidants are molecules that help neutralize free radicals, which are unstable atoms that can damage cells, leading to aging and diseases. They play a crucial role in protecting the body from oxidative stress, which is linked to conditions like cancer, cardiovascular diseases, and neurodegenerative disorders. Common antioxidants include vitamins C and E, selenium, and flavonoids found in various fruits and vegetables.

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community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 735 upvotes 1 year ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community What would be an ideal diet for promoting health for what's left/regrowth?

in Question 38 upvotes 5 years ago

The conversation discusses an ideal diet for promoting hair health, emphasizing biotin, collagen, vitamins C and E, zinc, selenium, anti-inflammatory foods, and blood circulation. It also mentions using finasteride, minoxidil, and dermarolling for hair regrowth.

community How much dht does Nizoral shampoo block?

in Ketoconazole 101 upvotes 2 years ago

Hair loss treatments discussed include Minoxidil, Finasteride, RU58841, and Nizoral shampoo. Nizoral's effectiveness is debated, with some suggesting it works as a weak antagonist for androgen receptors, while others attribute its benefits to anti-fungal and anti-inflammatory properties.

community New Study - Flavonoids More Effective Than Finasteride?

in Research/Science 148 upvotes 10 months ago

A recent publication suggests that the flavonoids eriocitrin and silymarin may be more effective than finasteride in binding to the enzyme responsible for hair loss. People in the conversation are skeptical about the effectiveness and safety of these flavonoids until tested on humans, and some discuss their personal experiences with other treatments.

community Reducing tension on the back, sides and top of head causes hair growth in MPB sufferers. Studies inside

15 upvotes 6 years ago

Reducing scalp tension can help reverse male pattern baldness (MPB). Firm scalp massages and scalp stretching exercises are beneficial.

community Anyone have experience with natural DHT blockers?

in Finasteride/Dutasteride 7 upvotes 10 months ago

The conversation is about using natural DHT blockers like pumpkin seed oil and saw palmetto extract for hair loss. The user has been using minoxidil, derma rolling, vitamin D, and biotin but is considering finasteride next.

community Aggressive Hair Loss from 18 – 22: Beginning my Holy Crusade Against MPB

in Treatment 1 year ago

A user's experience with aggressive hair loss from age 18-22, and possible treatments to combat this such as Dut, oral minoxidil, and finasteride.

community Interested about what other adjunct therapies people are trying & whats working?

in Treatment 9 upvotes 5 months ago

The conversation discusses alternative hair loss treatments beyond the commonly used Minoxidil and Finasteride. One user is trying diclofenac gel, caffeine + antioxidant serum, finasteride, ketoconazole shampoo, and has stopped using Minoxidil due to ineffectiveness, while another user has adopted lifestyle changes like exercise, diet, stress reduction, and topical caffeine, along with scalp massages and microneedling.

community Homemade Topical Finasteride Formula?

in Treatment 7 upvotes 2 years ago

User wants to make homemade topical finasteride to minimize side effects and asks about using glycerin, stirring time, storage, and alternative solvents. Another user's comment is unclear.

community Korean 2021 study shows efficacy of sulforaphane.

in Treatment 49 upvotes 2 years ago

Sulforaphane shows potential for hair regrowth, with users reporting reduced shedding and regrowth. Some users combine it with Minoxidil and finasteride for better results.

community 3 months 7 days fin 0.5mg /Min and derma

in Is this regrowth? 131 upvotes 6 months ago

The user has been using finasteride (0.5mg), minoxidil (5% foam), dermarolling, and rosemary oil for 3 months, noticing baby hairs and some shedding. Advice given includes continuing the current treatment, considering additional treatments, and potentially increasing the finasteride dose.

community People need to start accepting that only medical therapy (Fin/Dut) can save your hair in the long run.

in Treatment 110 upvotes 8 months ago

Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.

community Have people with aggressive balding genetics genuinely had any results after applying any natural remedies ie:rosemary oil,coconut oil,Onion Juice etc

in Research/Science 42 upvotes 10 months ago

Natural remedies like rosemary oil, coconut oil, and onion juice are generally seen as less effective compared to medical treatments like finasteride, minoxidil, and microneedling. Some users believe natural oils can help, but modern medicine is often more reliable.

community Started aggressively losing my hair at 16 and I'm now 30

in Progress Pictures 835 upvotes 1 year ago

The user started losing their hair at 16 and got a hair transplant. They used Minoxidil and finasteride as treatments. The transplant has held up well and they have not experienced graft loss.

community Got a microscope camera. Here’s the difference between healthy and miniaturized hair

in Progress Pictures 492 upvotes 2 years ago

A user who shared progress pictures of their scalp using a microscope camera, demonstrating the difference between healthy and miniaturized hair. Various explanations for the cause of this were discussed, such as DHT build-up in scalp sebum causing an autoimmune response leading to inflammation and eventual hair loss, with some suggesting a do-it-yourself treatment involving adding ascorbic acid powder to shampoo.

community Vitamin C and hair growth PH levels

in Product 34 upvotes 2 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community My strong recommendation for those shedding hair

in Treatment 96 upvotes 2 years ago

A user with aggressive male pattern baldness found that topical melatonin significantly reduced their hair shedding to 1 or 2 hairs per day and noticed some thickening of side hair. They tried many treatments like finasteride and minoxidil with little success, but topical melatonin showed immediate results in reducing hair loss.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 96 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community [Discussion] Interesting read on Vitamin E for hair loss I found

in Advice 16 upvotes 5 years ago

The conversation discusses using Vitamin E, Minoxidil, finasteride, and RU58841 for hair loss treatment. The link provided offers more information on the benefits of Vitamin E for hair loss.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 482 upvotes 1 month ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community 1 Year on just Fin 1mg 3 times/week

in Progress Pictures 841 upvotes 2 months ago

A user shared their one-year progress using finasteride 1mg three times a week, starting at age 25, with noticeable regrowth after three months and no side effects. Other users discussed their experiences with finasteride, minoxidil, microneedling, and dutasteride, noting varying results and side effects.

community Anyone here in the 0% like me?

in Finasteride/Dutasteride 46 upvotes 6 months ago

The user has tried topical minoxidil, oral minoxidil, finasteride, RU58841, and dermapen for over a year without seeing hair regrowth and has now switched to dutasteride, planning to continue until summer. Some responses suggest that no further hair loss could be considered progress, question the visibility of hair loss, and recommend trying vitamin D.

community Korea launches 1st OTC hair loss drug

in Treatment 32 upvotes 3 years ago

Korea launched its first OTC oral hair loss drug, dexpanthenol B5. Users discuss its anti-oxidative and anti-inflammatory effects but note a lack of efficacy studies.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 62 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

community The theory that explains everything. Please help me make this big!

in Research/Science 2444 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Study shows Minox alternative can increase hair density by 41%. Has anyone tried it?

9 upvotes 5 years ago

The conversation discusses using topical Melatonin for hair loss, which has shown an average increase in hair density of 41% in 6 months. The original poster is inquiring about others' experiences with Melatonin for this purpose.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community NMN Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress

in Research/Science 14 upvotes 3 months ago

NMN shows promise in promoting hair growth by reducing oxidative stress and weakening androgens. It may be a beneficial addition to hair loss treatments like Minoxidil and Finasteride.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 4 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.